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Medical crisis checklists in the emergency department : a simulation-based multi-institutional randomised controlled trial
Background: Studies carried out in simulated environments suggest that checklists improve the management of surgical and intensive care crises. Whether checklists improve the management of medical crises simulated in actual emergency departments (EDs) is unknown. Methods: Eight crises (anaphylactic shock, life-threatening asthma exacerbation, haemorrhagic shock from upper gastrointestinal bleeding
Shock deformation in zircon grains from the Mien impact structure, Sweden
Recognition of impact-induced deformation of minerals is crucial for the identification and confirmation of impact structures as well as for the understanding of shock wave behavior and crater formation. Shock deformed mineral grains from impact structures can also serve as important geochronometers, precisely dating the impact event. We investigated zircon grains from the Mien impact structure in
Gender Bias in Opinion Aggregation
Gender biases have been documented in many areas including hiring, promotion, or performance evaluations. Many of these decisions are made by committees. We experimentally investigate whether committee deliberation contributes to gender biases. In our experiments, participants perform a real effort task and then rate the task performance of other participants. Across treatments we vary the extent
PD-L1 amplification is associated with an immune cell rich phenotype in squamous cell cancer of the lung
Gene amplification is considered to be one responsible cause for upregulation of Programmed Death Ligand-1 (PD-L1) in non-small cell lung cancer (NSCLC) and to represent a specific molecular subgroup possibly associated with immunotherapy response. Our aim was to analyze the frequency of PD-L1 amplification, its relation to PD-L1 mRNA and protein expression, and to characterize the immune microenv
Interventions to minimize blood loss in very preterm infants - A systematic review and meta-analysis
Blood loss in the first days of life has been associated with increased morbidity and mortality in very preterm infants. In this systematic review we included randomized controlled trials comparing the effects of interventions to preserve blood volume in the infant from birth, reduce the need for sampling, or limit the blood sampled. Mortality and major neurodevelopmental disabilities were the pri
Two screening instruments for collecting alcohol-related information from expectant mothers and fathers : Testing the reliability of the Parent Alcohol Screening Questionnaire and the Social Support for an Alcohol-Free Pregnancy Questionnaire
The aim is to test the reliability of two alcohol screening instruments: (1) The Parent Alcohol Screening Questionnaire (PASQ5), and (2) the Social Support for an Alcohol-free Pregnancy (SSAFP) questionnaire. This is a cohort study from the south of Sweden using repeated surveys during pregnancy. To examine if responses differed according to different data collection methods, two cohorts consistin
Endovascular Relining of Chronically Occluded Infrainguinal Venous Bypass Grafts
Background: Treatment of chronically occluded infrainguinal venous bypass grafts in patients presenting with recurrent chronic limb threatening limb ischemia (CLTI) represent a clinical challenge. Recent case reports have suggested the use of endovascular recanalization techniques without preceding thrombolysis. This study assesses feasibility and mid-term outcomes of this technique. Results: A re
"Ingen förtjänar att dö" : En intervjustudie om hur individer i kriminella miljöer i Malmö ser på skjutvapenvåld och möjligheten att hoppa av
Rapporten är en intervjustudie med personer i kriminella miljöer i Malmö. Studien analyserar hur dessa individer själva ser på skjutvapenvåld och möjligheter att lämna en kriminell livsstil.Rapporten är en intervjustudie med personer i kriminella miljöer i Malmö, studien analyserar hur dessa individer själva ser på skjutvapenvåld och möjligheter att lämna en kriminell livsstil.
Analysis of Thermal Stress in a Solid Oxide Fuel Cell Due to the Sulfur Poisoning Interface of the Electrolyte and Cathode
The interface of an electrolyte and cathode strongly determines the oxygen reduction reaction and cell stability, but it is susceptible to sulfur impurities like SO2 in air. In this study, a 3D solid oxide fuel cell model is developed based on experimental characterization to reveal sulfur-deactivating active cathodes. The results indicate that both the average values for electric and ionic curren
Implementation of National Guidelines increased survival in advanced ovarian cancer - A population-based nationwide SweGCG study
Aim: The first Swedish National Guidelines for Ovarian Cancer (NGOC) were published in 2012. We aimed to evaluate surgical outcomes and survival in patients with stage IIIC-IV disease, before and after the NGOC implementation. Method: Women with primary epithelial ovarian cancer, FIGO stage IIIC–IV, registered in the Swedish Quality Registry for Gynecologic Cancer 2008–2011 and 2013–2016 were incl
Parallel consistency in constraint programming
Program parallelization becomes increasingly important when new multi-core architectures provide ways to improve performance. One of the greatest challenges of this development lies in programming parallel applications. Using declarative languages, such as constraint programming, can make the transition to parallelism easier by hiding the parallelization details in a framework. Automatic parallel
The uropygial gland microbiome of house sparrows with malaria infection
Birds secrete preen oil from the uropygial (preen) gland which is used to maintain feather integrity and communicate through odour. The uropygial secretion is believed to influence host attractiveness to biting insects, thereby altering the risk of infection by vector-transmitted blood parasites. Previous studies have documented a presence of bacteria in the uropygial secretion; however, the micro
A feasibility study of the Redesigning Daily Occupations (ReDOTM-10) programme in an Irish context
Background: Despite high demand, mental health services in primary care in Ireland are underdeveloped. People with mild/moderate anxiety, depression and unspecified psychological distress are frequently seen in primary care settings, mostly by general practitioners (GPs). Occupational therapists have the potential to contribute to service-provision with interventions specially designed for the tar
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Evaluation of 92 cardiovascular proteins in dried blood spots collected under field-conditions : Off-the-shelf affinity-based multiplexed assays work well, allowing for simplified sample collection
Workplace-collected blood spots deposited on filter paper were analysed with multiplexed affinity-based protein assays and found to be suitable for proteomics analysis. The protein extension assay (PEA) was used to characterize 92 proteins using 1.2 mm punches in repeated samples collected from 20 workers. Overall, 97.8% of the samples and 91.3% of the analysed proteins passed quality control. Bot
Fostering regional innovation, entrepreneurship and growth through public procurement
Abstract: RIS3 is a policy initiative aiming to achieve structural change. Structural change needs to consider the processes and means through which (innovation) policies can facilitate a radical transformation by substantially changing a regional economy’s competitive bases. In this paper, we are interested in studying how certain policy instruments are actually implemented, and how the capabilit
High prevalence of ascending aortic dilation in adults with repaired coarctation of the aorta
Background: Ascending aortic dilation is a feared complication in adults with repaired coarctation of the aorta, as the condition is associated with life-threatening complications such as aortic dissection and rupture. However, the data are currently limited regarding factors associated with ascending aortic dilation in these patients. Methods and results: From the national register of congenital
Cerebral autoregulation in infants during sevoflurane anesthesia for craniofacial surgery
Background: Data on cerebral pressure-flow autoregulation in the youngest children are scarce. We studied the correlation between mean arterial pressure and cerebral tissue oxygen saturation (rSO2) by near-infrared spectroscopy (NIRS) in patients undergoing nose, lip, and palate surgery. Aim: We tested the hypothesis that cerebral pressure-flow autoregulation is impaired in children less than 1 ye
ISPD recommendations for the evaluation of peritoneal membrane dysfunction in adults : Classification, measurement, interpretation and rationale for intervention
Peritoneal dialysis (PD) uses the peritoneal membrane for dialysis. The peritoneal membrane is a thin layer of tissue that lines the abdomen. The lining is used as a filter to help remove extra fluid and poisonous waste from the blood. Everybody is unique. What is normal for one person’s membrane may be very different from another person’s. The kidney care team wants to provide each person with th