Novel Chromatography Matrices for Fast Isolation of Plasmid DNA
As new therapeutic areas in which genetic material is employed, i.e. gene therapy and DNA vaccination, are expanding, a substantial increase in the demand for gene vectors, e.g. plasmid DNA, is foreseen. Chromatography, being a high-resolution method, is considered essential for the purification of gene vectors when high purity is required. Plasmids are large molecules, which cannot penetrate the