Background: Osteoarthritis of the knee involving predominantly the medial tibiofemoral compartment is common in older people, giving rise to pain and loss of function. Many people experience progressive worsening of the disease over time, particularly those with varus malalignment and increased medial knee joint load. Therefore, interventions that can reduce excessive medial knee loading may be be

The incidence of the most common fracture types in Iceland is reported based on individual data from the Reykjavik Study 1967-2008. Time trend is reported for the major osteoporotic fractures (MOS) 1989-2008. This study aims to assess the incidence of all fractures in Iceland, with emphasis on the rate of hip fractures, and compare the incidence with other populations as well as examine the secula

Fractional exhaled nitric oxide is elevated in allergen-provoked asthma. The cellular and molecular source of the elevated fractional exhaled nitric oxide is, however, uncertain.

This paper presents one approach to the absorption and scattering of light from aggregates of primary particles. The primary particles are sphere like and small compared to the wavelength, whereas the aggregate can be large compared to the wavelength. This situation applies to when soot particles formed in flames are measured using methods based on laser light. The method presented in this work, c

Den brittiske filosofen och matematikern Alfred North Whitehead har i ett av sina mer berömda citat sagt att den västerländska filosofihistorien är en serie fotnoter till Platon. På samma sätt kan retorikhistorien sägas vara en serie fotnoter till Aristoteles Retorik. När nu detta inflytelserika verk för första gången finns tillgängligt på svenska kan det vara på sin plats att säga något om detta

ALICE is the heavy-ion experiment at the CERN Large Hadron Collider. The experiment continuously took data during the first physics campaign of the machine from fall 2009 until early 2013, using proton and lead-ion beams. In this paper we describe the running environment and the data handling procedures, and discuss the performance of the ALICE detectors and analysis methods for various physics ob

The purpose of the present study is to determine the feasibility of estimating respiratory information from the built-in pressure sensors of a dialysis machine. The study database consists of simultaneous recordings of pressure signals and capnographic signals from 6 patients during 7 hemodialysis treatment sessions. Respiration rates were estimated using respiratory induced variations in the beat

Imaging is an integral part of an aortic program. Careful preoperative planning is essential to successful evaluation and treatment of aortic pathology. Computed tomography angiography (CTA) is the dominant modality for such preoperative planning. The use of a dedicated workstation for 3D postprocessing is very favorable and is considered mandatory when treating complex aortic pathology. Intraoper

Disaster recovery after the Indian Ocean tsunami in 2004 led to a number of challenges and raised issues concerning land rights and housing reconstruction in the affected countries. This paper discusses the resistance to relocation of fishing communities in Chennai, India. Qualitative research methods were used to describe complexities in the debate between the state and the community regarding re

Popular Abstract in Swedish β-celler producerar insulin som frisätts när blodsockret höjs, t.ex. efter en måltid. Patienter med diabetes saknar de insulinproducerande β-cellerna eller har nedsatt känslighet för insulin. För de patienter som saknar insulin kan det vara svårt att reglera blodsockernivåerna i blodet trots dagliga injektioner med insulin, varför transplanterbara insulinproducerande β-Organogenesis of epithelial organs requires interaction between epithelial and mesenchymal tissues. During pancreas development, mesenchyme-derived structures induce specification, growth and differentiation of pancreatic epithelial cells. For instance, notochord, endothelial cells, and pancreatic mesenchyme are essential for the development of the pancreas. N-cadherin deficient-embryos suffer fro

The liquid argon calorimeter is a key component of the ATLAS detector installed at the CERN Large Hadron Collider. The primary purpose of this calorimeter is the measurement of electron and photon kinematic properties. It also provides a crucial input for measuring jets and missing transverse momentum. An advanced data monitoring procedure was designed to quickly identify issues that would affect

The interactions between DNA and a number of different cationic surfactants, differing in headgroup polarity, were investigated by electric conductivity measurements and fluorescence microscopy. It was observed that, the critical association concentration (cac), characterizing the onset of surfactant binding to DNA, does not vary significantly with the architecture of the headgroup. However, compa

In 1914 Professor Nathan Soderblom was elected archbishop of the Church of Sweden. His consecration took place in Uppsala Cathedral just months after the beginning of World War I. In 1925, he convened an ecumenical meeting in Stockholm that came to shape the ecumenical movement for decades to come. The peace question remained at the heart of his episcopate as long as it lasted. In this article, An

Acute lung injury (ALI) is an important cause of mortality in critically ill patients. Acute pancreatitis (AP) is one of the risk factors for developing this syndrome. Among the inflammatory cells, macrophages have a key role in determining the severity of the acute lung injury. In the lungs, macrophages constitute a heterogeneous cell population distributed in different compartments. Changes in n

Background: Fluorescent light (FL)-guided cystoscopy induced by 5-aminolevulinic acid (5-ALA) has been reported to detect more tumours compared with standard white-light (WL) cystoscopy. Most reports are from single centres with relatively few patients. Objective: To evaluate whether 5-ALA-induced FL and WL cystoscopy at transurethral resection (TUR) is superior compared with standard procedures u

What role does attention to different object properties play in early vocabulary development? This longitudinal study using event-related potentials in combination with behavioral measures investigated 20- and 24-month-olds’ (n = 38; n = 34; overlapping n = 24) ability to use object shape and object part information in word-object mapping. The N400 component was used to measure semantic priming by

Background: Antithrombin concentrate (AT) is used to treat heparin resistance (HR) in cardiac surgery. It is usually given slowly due to the fear of anaphylaxis. This may delay cardiac catheterisation and the start of cardiopulmonary bypass (CPB). HR is often defined as the failure to reach or maintain a target activated clotting time (ACT) despite a standard dose of heparin. It is not generally p

abstract is not available

Popular Abstract in Swedish Akut bukspottkörtelinflammation, akut pankreatit (AP), är en sjukdom med varierande kliniska presentationer; från en mild och ödematös, till en svår och nekrotiserande form. Ungefär 75% av patienter med AP utvecklar en mild, självbegränsande sjukdom, men hos resten av patienterna progredierar sjukdomen till en svår form och dödligheten är så hög som 30% i denna grupp avAcute pancreatitis (AP) is an inflammatory disease with variable severity ranging from mild interstitial edematous to severe necrotizing disease. The overall mortality rate of AP is 8-9%. Specific treatment of AP is lacking which is partly related to an incomplete understanding of the basic pathophysiology behind the disease. It is widely held that premature intra-cellular trypsinogen activation a