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Eating and drinking abilities and nutritional status in children with cerebral palsy : A population-based study

Aim: To investigate the prevalence of eating and drinking difficulties as classified with the Eating and Drinking Ability Classification System (EDACS) in a large population-based cohort of children with cerebral palsy (CP) at all levels of motor function, and how EDACS classifications relate to undernutrition. Method: This was a cross-sectional study based on data from the Swedish CP follow-up pr

Boat-to-Grid for Marine Leisure Drivelines : A Swedish Case Study on Evaluating Lifecycle CO2-Equivalent Emissions and Profitability

Lithium-ion batteries (LIBs), particularly Nickel-Cobalt-Aluminum (NCA) variants, are widely recognized as essential for applications such as electric vehicles, renewable energy storage, and portable electronics. The superior energy density, extended lifespan, and thermal stability of NCA batteries make them a preferred choice for demanding applications, including electric marine propulsion. In th

Disentangling the Climate–VPD–GPP Nexus: Global Patterns and Underlying Drivers

Atmospheric vapor pressure deficit (VPD) is a key climatic factor that influences vegetation productivity and the global carbon cycle. With ongoing climate warming, VPD has been rising globally. However, the effects of this increase on gross primary production (GPP), especially under different driving mechanisms, remain unclear. This uncertainty limits our ability to predict terrestrial ecosystem

Arts and culture engagement for health : a Danish population-based follow-up study

Aims: Using a longitudinal approach, the aim of this study was to examine whether baseline engagement in arts and culture was associated with a decline from ‘Good’ to ‘Poor’ health at follow-up. Methods: Self-rated health (SRH) and engagement in six cultural activities among randomly selected Danish adults (⩾15 years) were assessed using data from the Danish Health and Wellbeing Survey in 2019. On

Environmentally-dependent wood density influences forest structure and dynamics in a demographic vegetation model

Wood density is a crucial anatomical trait influencing forest carbon storage. However, dynamic global vegetation models (DGVMs) typically assume a fixed species-level wood density, neglecting environment-driven variability. In this proof-of-concept study, we explore the potential impact of dynamic wood density on tree- and forest-level carbon storage by integrating a simple temperature-response fu

Concurrently fading away and strengthening : A cross-country comparison of foreign and local news beats

One of the structuring logics behind the creation of news beats is the geographical one: that is, national, foreign and local news desks. Foreign and local beats, in particular, have a lot in common: the coverage of different geographical contexts increases the diversity and plurality of views; reporting from geographical peripheries is always the costliest in terms of production; the audience is

Risk factor management over two decades in hospitalised patients with chronic limb-threatening ischaemia with and without diabetes mellitus

Background: Chronic limb-threatening ischaemia (CLTI) causes high rates of amputation and mortality. Objectives: To compare incidence, management and prognosis in hospitalised patients with CLTI with and without diabetes mellitus (DM) in 2001 and 2023. A secondary objective was to compare adherence to global vascular guidelines on risk factors between patients with and without DM in 2023. Design:

Machine learning techniques to model child low height-for-age in the Northern Province of Rwanda : The role of climatological and environmental factors and their interactions

Objective: Childhood stunting is a significant health issue in Rwanda, particularly within the Northern Province. While demographic and socio-economic factors have been more extensively studied, the impact of environmental and climatic factors on stunting prevalence has received less attention. This study aimed to determine if these factors could be used to better predict localized variations in h

Optimizing a Multi-Scale Cellular Structure for Urban Growth Modeling Using NSGA-II

In urban growth modeling methods, researchers typically determine an appropriate scale based on various factors such as the extent of the study area, the scale of available data, and the level of detail required. With rapid urbanization, cities and towns have grown dramatically, leading to the emergence of numerous megalopolitan areas worldwide. In these areas, which include small and large cities

Animal friendly and durable attachment for the future

This master thesis aims to improve the physical design of smart ear tags for animals. The focus was to minimize the risk of tags falling off or causing harm, while considering environmental and animal welfare aspects. The project followed the methodology of Ulrich & Eppinger’s product development process, which included stages such as planning, concept development, and testing. Data collectio

Evaluation of Novel DNA Adenine Methyltransferase Fusion Construct Designs for Enhancer Mapping in Human Cells

Enhancers are central regulators of cell-type-specific gene expression, yet direct functional mapping of active enhancer-promoter interactions in single cells remains technically challenging. DNA adenine methyltransferase (Dam)-based chromatin recording offers a strategy to mark genomic regions proximal to proteins associated with active transcription sites in vivo, including enhancer regions, and

Perioperative trajectories of acute-phase proteins and their association with major postoperative complications in advanced ovarian cancer

BackgroundAcute-phase proteins (APPs) reflect systemic inflammation and nutritional status, yet their perioperative trajectories and clinical utility as biomarkers of outcome in advanced ovarian cancer (aEOC) remain unclear. We aimed to characterise perioperative APP fluctuations and assess their associations with postoperative complications.MethodsThis observational study included patients underg

Etiology of apneic episodes in infants aged <1 year and validation of brief resolved unexplained events risk-stratification criteria without age as a risk factor

The criteria for Brief Resolved Unexplained Events (BRUE) are used to stratify the risk in infants presenting with apneic episodes. However, these criteria often classify a high proportion of infants as higher risk. This study aimed to investigate the etiology of apneic episodes, particularly those compatible with BRUE, and to assess whether age ≤60 days is associated with serious underlying condi

Disruption of CSF-1 receptor-mediated metal ion homeostasis in the murine brain promotes neurodegenerative disease

Dominant-inactivating mutations in the colony stimulating factor-1 receptor (CSF1R) cause CSF-1R related leukoencephalopathy (CRL), an adult-onset neurodegenerative disease that is modeled in the Csf1r+/– mouse. CRL is caused by microglial dysfunction. However, the primary microglial deficit, is unknown. To address this question, we employed single-nucleus RNA sequencing of brains from young Csf1r

Exploring the geography of innovation and sustainability transitions in the bioeconomy

This editorial introduces the special issue on the geography of innovation and sustainability transitions in the bioeconomy, situating the bioeconomy as a policy-driven transformation project with strong regional and multi-scalar implications. The special issue contains six papers that focus on different parts of the bioeconomy and employ a wide range of empirical approaches; jointly, they provide

Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence

UNLABELLED: In prostate cancer, androgen receptor (AR)-targeting agents are very effective in various disease stages. However, therapy resistance inevitably occurs, and little is known about how tumor cells adapt to bypass AR suppression. Here, we performed integrative multiomics analyses on tissues isolated before and after 3 months of AR-targeting enzalutamide monotherapy from patients with high