For clinical proteomic studies the availability of high quality biofluid samples such as human blood plasma are extremely important. In this study we have investigated the stability of human plasma samples by spiking stable isotope-labeled peptides into the plasma and monitoring their degradation under different storage conditions. FPA-1, C4A and C3f were synthesized with isotopically labeled amin

Measurements of four-lepton (4ℓ, ℓ=e,μ) production cross sections at the Z resonance in pp collisions at the LHC with the ATLAS detector are presented. For dilepton and four-lepton invariant mass regions m_{ℓ^{+}ℓ^{-}}>5 GeV and 80

Molecular spiders are synthetic biomolecular walkers that use the asymmetry resulting from cleavage of their tracks to bias the direction of their stepping motion. Using Monte Carlo simulations that implement the Gillespie algorithm, we investigate the dependence of the biased motion of molecular spiders, along with binding time and processivity, on tunable experimental parameters, such as number

This concerns Flow Induced Vibrations (Fly) in nuclear reactors and numerical analysis of such. Special attention is paid to structural excitation by sound generated remotely and turbulent flow around the structure. One hypothesis was that these phenomena can interact, so that the structure accumulates more energy from the flow if it also excited by sound from another source. In the studies, Fluid

ECG markers derived from the P-wave are used frequently to assess atrial function and anatomy, e.g. left atrial enlargement. While having the advantage of being routinely acquired, the processes underlying the genesis of the P-wave are not understood in their entirety. Particularly the distinct contributions of the two atria have not been analyzed mechanistically. We used an in silico approach to

Semiconductor devices are heavily dependent on dopant incorporation in order to control the electrical properties. In this paper we investigate the possibility of using gates wrapped around a nanowire (NW) channel as a way of tuning the Fermi level position, in certain cases removing the need for dopants and providing a more dynamical way of setting the device properties. InP NW devices with omega

The proportion of patients who die during or after surgery, otherwise known as the perioperative mortality rate (POMR), is a credible indicator of the safety and quality of operative care. Its accuracy and usefulness as a metric, however, particularly one that enables valid comparisons over time or between jurisdictions, has been limited by lack of a standardized approach to measurement and calcul

The aim of this paper is to explore the relation between the critical knowledge base of firms and how firms respond to incentives embedded in the institutional framework surrounding them. The analysis gives us a better understanding of the complex development of the food sector in Southern Sweden in the past decades. Theoretically, the paper combines concepts of path dependency and knowledge bases

Objective:To evaluate reliability, internal consistency and construct validity of the Posture and Postural Ability Scale for adults with cerebral palsy.Design:Psychometric evaluation of a clinical assessment tool.Setting:Rehabilitation centres in Sweden and Iceland.Subjects:Thirty adults with cerebral palsy aged 19-22 years, six people at each level I-V of the Gross Motor Function Classification S

3-Hydroxypropionic acid (3-HP) is an important platform chemical for the biobased chemical industry. Lactobacillus reuteri produces 3-HP from glycerol via 3-hydroxypropionaldehyde (3-HPA) through a CoA-dependent propanediol utilization (Pdu) pathway. This study was performed to verify and evaluate the pathway comprising propionaldehyde dehydrogenase (PduP), phosphotransacylase (PduL), and propiona

AIM To study the value and reliability of an examination of neurological soft-signs, often used in Sweden, in the assessment of children with attentiondeficit– hyperactivity disorder (ADHD), by examining children with and without ADHD, as diagnosed by an experienced clinician using the DSM-III-R. METHOD We have examined interrater reliability (26males, nine females; age range 5y 6mo–11y), internal

Let A be a commutative and associative ring (not necessarily unital), G a group and α a partial action of G on ideals of A, all of which have local units. We show that A is maximal commutative in the partial skew group ring A*G if and only if A has the ideal intersection property in A*G. From this we derive a criterion for simplicity of A*G in terms of maximal commutativity and G-simplicity of A.

Magmatic Ni-Cu sulphide deposits are commonly associated with mafic rocks within the marginal areas of Archean or Proterozoic cratons. The Kleva Ni-Cu sulphide deposit in southeast Sweden is hosted by gabbro-diorite rocks and is sandwiched between two Palaeoproterozoic magmatic arcs: the Transscandinavian Igneous Belt (TIB) and the Oskarshamn-Jonkoping Belt (OJB). Major and trace element data corr

The aim was to explore radiotherapy nurses' perceptions of their experiences of caring for children undergoing radiotherapy treatment for cancer.

Background: During the last few years many new human picornaviruses have been discovered due to advances in metagenomics and other molecular biological approaches. The clinical significance and the occurrence are only sparsely described. Objectives: To determine the epidemiology and clinical significance of infections with the novel human picornaviruses, aichi virus, cosavirus, salivirus, and saff

The most common forms of familial thrombophilia are factor V Leiden (FVL) and prothrombin mutation (PTM). Homozygous FVL and PTM have long been feared conditions thought to cause high rates of morbidity and mortality. To analyse clinical features in patients with homozygous FVL and PTM, as well as patients with double heterozygosity for FVL and PTM. All patients with homozygous FVL, PTM or double

Thiazide diuretics have been recommended as a first-line antihypertensive treatment, although the choice of 'the right drug in the individual essential hypertensive patient' remains still empirical. Essential hypertension is a complex, polygenic disease derived from the interaction of patient's genetic background with the environment. Pharmacogenomics could be a useful tool to pinpoint gene varian

Abstract: The social relationship between sales assistants and customers has often been described as relatively one-sided one in which sales assistants are subordinate to customers. One of the ways in which the subordination of sales assistants is manifested is when customers treat them badly, for instance in the form of verbal and physical abuse. We suggest that these power relations are not one-

For the amine transaminase (ATA)-catalyzed synthesis of chiral amines, the choice of donor substrate is of high importance for reaction and process design. Alanine was investigated as an amine donor for the reductive amination of a poorly water-soluble ketone (4-phenyl-2-butanone) in a combined in situ product removal (ISPR) approach using liquid-membrane extraction together with an enzyme cascade