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Droplet splitting plays an important role in droplet microfluidics by providing precise control over droplet size, which is essential for applications such as single-cell analysis, biochemical reactions, and the fabrication of micro- and nanosized material. Conventional methods of droplet splitting using obstructions or junctions in the microchannel have a clear limitation that the split ratio for
This study investigates the wages and labour contracts of Khoe workers in Graaff Reinet, a district on the Cape Colony’s eastern frontier in the early nineteenth century. Using wage registers from 1801 to 1810, we offer the first individual-level analysis of wages for both male and female Khoe workers, examining payment forms, socio-economic stratification, and gendered wage dynamics. The findings
Background: The use of unique national personal identification numbers (PIN) for linkage of medical records across health facilities and population-based studies is limited in sub-Saharan Africa (SSA) countries. The disintegration of healthcare research with different participant identifiers creates methodological challenges in linking data from multiple sources to answer a diverse range of policy
We assessed hepatocellular carcinoma (HCC) risk associated with smoking and alcohol consumption and their interactions, using both questionnaire data and objective serum biomarkers. Information on smoking and alcohol consumption was collected at baseline from 450,112 participants of the EPIC cohort, among whom 255 developed HCC after a median follow-up of 14 years. In a nested case–control subset
This book presents recent advancements, challenges, and clinical implications of molecular biomarkers in various cancers. This book highlights the clinical applications of biomarkers are extensive for cancer risk assessment, screening and early detection of cancer, accurate diagnosis, patient prognosis, prediction of response to therapy, and cancer surveillance and monitoring response. It also exp
Background: Virtual consultations represent a notable change in health care delivery following the COVID-19 pandemic. Understanding the dynamics of virtual consultations is critical in assessing health care system resilience and adaptability in times of crisis. Objective: This study aimed to describe the availability and hours of use of telephone, video, and human chat consultations before and dur
The human influence on Earth's ecosystems is omnipresent. Artificial light at night (ALAN), anthropogenic noise, and air pollution are inherent features of human activities and infrastructure and pose novel environmental challenges to urban-dwelling wildlife. So far, most of the studies investigating the impacts of exposure to urban pollutants on animals have either investigated the effects of urb
The impact of livestock grazing on soil organic carbon (SOC) stocks in the Sahel has been poorly documented due to a lack of data from different grazing intensities. This study evaluated SOC stocks under four grazing intensities within 0–30 cm soil depth in dry savanna ecosystems of Senegal. It also examined possible indirect relationships between grazing and SOC through herbaceous species diversi
Spectroscopic imaging is a widely employed diagnostic approach with applications span-ning several different disciplines. Although color-sensitive cameras are very common and used for everyday photography, scientific applications often require highly specific color sensitivity to avoid signal cross-talk and misinterpretations. Such systems are primarily based on sequential acquisition configuratio
This paper implements and validates a real-time Energy Management System (EMS) for DC microgrid operation using a power hardware-in-the-loop (PHIL) test bench. The test bench replicates renewable sources, a general load, and a Hybrid Energy Storage System (ESS) comprising a battery, an emulated fuel cell, an emulated electrolyzer, and a virtual hydrogen tank. Constructed with dSPACE and Simulink,
We use the introduction of covered bonds in Norway in 2007 together with administrative and supervisory data at the bank and loan level to investigate the effect of asset encumbrance, that is, pledging assets as collateral, on the composition of bank balance sheets and bank risk. We show that covered bonds—despite being collateralized with mortgages—lead to a shift in bank lending from mortgages t
Using a new dataset on fossil fuel funding, this paper examines bank responses to Germany’s 2020 coal phase-out decision. German banks reduced fossil fuel financing relative to other banks but not coal funding. Globally, banks increased underwriting for coal companies relative to other fossil fuel firms. Firms with entirely coal-based post-sample power production received more funding, indicating
The incidence of melanoma is rising and will require more efficient diagnostic procedures to meet a growing demand. Excisional biopsy and histopathology is still the standard, which often requires multiple surgical incisions with increasing margins due inaccurate visual assessment of where the melanoma borders to healthy tissue. This challenge stems, in part, from the inability to reliably delinea
Japan’s problem of vacant homes has drawn global media attention, but the situation may not be as dire as once predicted. While a 2015 report estimated a vacancy rate of 20.1 per cent by 2023, the actual figure was 13.8 per cent, thanks in part to policy reforms, awareness campaigns and grassroots efforts. Yet challenges remain amid an ageing population. Japan’s evolving approach offers valuable l
Investigating metal-semiconductor interfaces is crucial for enabling ultra-thin film growth and tuning the electronic properties. Here we have studied the atomic mechanism of Bi incorporation into the surface of InSb, the III-V semiconductor with the largest spin-orbit coupling, using surface science techniques and theoretical modeling. Bi deposition onto Sb-terminated InSb(111) surfaces at elevat
