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Professors Carl Borrebaeck, Thoas Fioretos, Lao Saal and Åke Borg share their experiences in transforming groundbreaking research into diagnostic tools, treatments, and biotech companies. From navigating commercialization strategies and securing long-term funding to building strong teams and mentoring future innovators, they reflect on what it truly takes to make science matter—outside the lab. Th

https://www.medicine.lu.se/article/how-turn-research-ideas-real-world-impact - 2025-10-03

Congratulations to Charlotte Ling who, together with Katarina Fagher and Alice Maguolo, has been awarded a grant of five million Danish kroner by the Novo Nordisk Foundation. The funding will support clinical research in precision medicine, focusing on epigenetic analysis of blood samples from 13,000 individuals. Epigenetic research paves the way for tailored type 2 diabetes treatmentCharlotte Lin

https://www.medicine.lu.se/article/charlotte-ling-receives-major-grant-clinical-diabetes-research - 2025-10-03

An experimental study from Lund University reveals for the first time that different Parkinson’s medications affect brain activity in distinct ways. This could explain why some patients develop impulsive and compulsive behaviors as a result of their treatment. The findings have been published in NPJ Parkinson’s Disease. Upon receiving treatment for their motor symptoms, many patients with Parkinso

https://www.medicine.lu.se/article/brain-activation-pattern-behind-impulsivity-parkinsons-treatment-discovered - 2025-10-03

In June, pediatric cancer experts from 16 countries gathered in Brussels for the annual meeting of the NOPHO-DB-SHIP consortium—an EU-wide collaboration working to improve outcomes for children with Acute Myeloid Leukemia (AML). In Sweden, the trial is coordinated by Lund University and Skåne University Hospital. At the center of this collaboration is the CHIP-AML22 trial—an international phase II

https://www.medicine.lu.se/article/brussels-meeting-advancing-personalised-treatment-childhood-aml-across-europe - 2025-10-03

A new study led by researchers at Lund University in Sweden, reveals that melanoma, the deadliest form of skin cancer, can in some cases be driven by mitochondrial processes, which can be effectively targeted using existing drugs. In preclinical laboratory experiments with melanoma cell cultures, researchers successfully eliminated cancer cells by using antibiotics and inhibitors of mitochondrial

https://www.medicine.lu.se/article/aggressive-skin-cancer-driven-mitochondrial-processes-existing-drugs-offer-promising-treatment-path - 2025-10-03

An international research team led from Lund University, has identified epigenetic biomarkers that can predict which people with type 2 diabetes are at risk of cardiovascular disease. The study is now published in Cell Reports Medicine. People with type 2 diabetes are up to four times more likely to have heart attacks, strokes, anginas and other coronary heart diseases than healthy people. Therefo

https://www.medicine.lu.se/article/biomarkers-reveal-risk-cardiovascular-disease-type-2-diabetes - 2025-10-03

In a new observational study, researchers at Lund University in Sweden looked at all children listed for heart transplants in the Nordic countries between 1986 and 2023. A total of 597 children were included in the study, 461 of whom received a transplant. The results show that survival rates have increased significantly over time despite the modest volumes in the region – a development that the r

https://www.medicine.lu.se/article/children-waiting-new-heart-study-shows-marked-improvement-survival-rates-and-importance-nordic - 2025-10-03

Type 2 diabetes is a chronic disease that usually requires lifelong treatment. A central goal for many diabetes researchers is to develop new cell therapies that can cure the disease. The Bo and Kerstin Hjelt Diabetes Foundation provides support to two diabetes researchers at Lund University Diabetes Centre who contribute with new knowledge to this research field. Type 1 diabetes is a condition wh

https://www.medicine.lu.se/article/hjelt-diabetes-foundation-supports-research-can-pave-way-new-cell-therapies - 2025-10-03

For decades, large stretches of human DNA were dismissed as ‘junk’ and considered to serve no real purpose. In a new study in Cell Genomics, researchers at Lund University in Sweden show that the repetitive part of the human genome plays an active role during early brain development and may also be relevant for understanding brain diseases. DNA carries the complete set of instructions an organism

https://www.medicine.lu.se/article/why-repetitive-dna-matters-human-brain-evolution-and-disease-0 - 2025-10-03

An international team led by researchers at Lund University in Sweden has identified the molecular tools needed to reprogram ordinary cells into specialised immune cells. The discovery, published in Immunity, could pave the way for more precise and personalised cancer immunotherapies. The team has taken an important step toward harnessing the immune system to fight cancer. Their work describes how

https://www.medicine.lu.se/article/scientists-uncover-cellular-toolkit-reprogram-immune-cells-cancer-therapy - 2025-10-03

A simple urine test that can assess the risk of kidney cancer recurrence at an early stage could spare patients from frequent imaging scans, e.g. CT-scans, and thus reduce the associated radiation, anxiety and costs. This has been shown in a new international research study led by Lund University in Sweden. The results have now been published in European Urology Oncology. Globally, about 400,000 p

https://www.medicine.lu.se/article/urine-test-can-assess-risk-kidney-cancer-recurrence - 2025-10-03

A new international commission will pave the way for a global boost in maternal and newborn health. The project is led by a researcher at Lund University in Sweden, whose motivation stems from a formative experience witnessing a woman bleed to death unnecessarily during childbirth. “The time has come to put maternal and newborn health back at the heart of the global health agenda,” says Mehreen Za

https://www.medicine.lu.se/article/new-global-initiative-maternal-and-newborn-health-be-led - 2025-10-03

Congratulations to Jacob Vogel and Camila Consiglio who have been awarded grants to develop their research projects on Alzheimer's and fertility. Camila Consiglio's research focuses on infertility and the immune system that plays a central role in determining reproductive success. Jacob Vogel and his research team will develop computational simulations of Alzheimer’s disease enabling virtual exper

https://www.medicine.lu.se/article/erc-grants-awarded-research-interplay-between-immunology-and-fertility-and-alzheimers-disease - 2025-10-03

From Nobel Prizes to visions of the future – over a few days in May, world-leading medical researchers and biotech pioneers gathered to discuss new molecular therapies: from genetic fundamentals to clinical breakthroughs in patients. The program spanned everything from cutting-edge basic science to new treatment principles in drug development. Three intense days marked by curiosity, persistence, a

https://www.medicine.lu.se/article/highlights-lund-spring-symposium-2025 - 2025-10-03

At this year’s Lund Spring Symposium, two veteran leaders of pharmaceutical research – Jan M. Lundberg and Mikael Dolsten – engaged in a wide-ranging conversation about scientific courage, setbacks, technological leaps, and hope for the future. The 2025 edition of the symposium, held in May, was filled with highlights. Among them was the thought-provoking exchange between Mikael Dolsten, former Ch

https://www.medicine.lu.se/article/science-responsibility-and-resilience-conversation-future-medicines - 2025-10-03

The information age predates the internet by a long stretch – it began with life itself. Nobel Laureate Craig C. Mello described at the Lund Spring Symposium in May how living organisms are not merely carriers of genes, but also active managers, defenders, and editors of genetic information. Craig Mello, who received the Nobel Prize in 2006 for the discovery of RNA interference (RNAi), together wi

https://www.medicine.lu.se/article/rnai-genetic-spark-information-inferno-cell - 2025-10-03

LUND SPRING SYMPOSIUM – When Katherine A. High began working with gene therapy, the field was new, promising – and riddled with uncertainty. Three decades later, she is a visiting professor at The Rockefeller University, CEO of RhyGaze AG, and former President and Head of R&D at Spark Therapeutics. Her research has led to life-changing treatments for patients with inherited diseases. But the road

https://www.medicine.lu.se/article/rewriting-genetic-fate-katherine-high-and-rise-gene-therapy - 2025-10-03

An innovative IVF test and a methane detector – these are some of the future innovation stars developed at Lund University. They are now being recognised by the University and Sparbanken Skåne. Since its launch in 2017, the Future Innovations Award has recognised ideas that can “change our world for the better”. This year, the awards were worth a total of SEK 800,000.The top prize this year goes t

https://www.medicine.lu.se/article/innovative-ideas-and-pioneering-solutions-lund-university-celebrated - 2025-10-03

Professor Thoas Fioretos is the first recipient of Lunds Innovatörspris (the Lund Innovator Award), a newly established prize that recognises research that has been successfully transformed into innovation with a tangible impact on society and the environment. Fioretos receives the award for his pioneering work in blood cancer research and his ability to translate scientific discoveries into life-

https://www.medicine.lu.se/article/award-winning-cancer-researcher-revolutionises-diagnosis-and-treatment-worldwide - 2025-10-03

Researchers at Lund University in Sweden have developed a digital cognitive test for diagnosing Alzheimer's disease that is intended for use in primary care. “This digital test, which patients perform on their own with minimal involvement from healthcare personnel, improves the primary care physician's ability to determine who should be further examined by blood tests for Alzheimer's pathology ear

https://www.medicine.lu.se/article/new-digital-cognitive-test-diagnosing-alzheimers-disease - 2025-10-03