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BACKGROUND AND AIM: Hepatorenal syndrome (HRS) occurs in about 20 % of patients with liver cirrhosis and ascites and is characterized by intensive renal vasoconstriction, low glomerular filtration rate but preserved tubular function and normal renal histology. The potential of terlipressin and albumin to reverse HRS after a time period of 14 days has already been shown. However, intravenous albumi
This study explores how insights from critical disability studies and critical disaster studies can inform more inclusive approaches to disaster risk reduction (DRR). Although disability-inclusive DRR policies call for the involvement of disabled people, structural ableism and unequal power relations can limit participation. While critical disaster studies increasingly considers marginalized popul
Context. Intermediate mass galaxies, including the Milky Way, typically host both a supermassive black hole (SMBH) and a nuclear stellar cluster (NSC). Binary systems residing in an NSC evolve dynamically via frequent close encounters with surrounding stars and secular processes related to the SMBH. Aims. Although the evolution of very soft and very hard binaries can be predicted semi-analytically
Tropical cyclones (TCs) pose significant threats to life and property across global ocean basins, and forecasting their structural evolution, track, and intensity remains a major scientific challenge. This review synthesizes the current understanding of TCs across major basins, that is, the Pacific, Atlantic, and North Indian Oceans, with a focus on the key environmental factors influencing TC beh
Following the development of regression-based methods to estimate natural and sexual selection, evolutionary biologists have quantified the strength, mode, and direction of selection in natural populations. Although this approach has been successful, its limitations include the lack of replication across species, which compromises the generality of the inferences beyond microevolutionary time scal
Background: Direct oral anticoagulants (DOACs) reduce the rate of thromboembolism in patients with atrial fibrillation but the benefits and risks in survivors of intracerebral haemorrhage are uncertain. We aimed to determine whether DOACs reduce the risk of ischaemic stroke without substantially increasing the risk of recurrent intracerebral haemorrhage. Methods: PRESTIGE-AF is a multicentre, open
Tensor-valued encoding in diffusion MRI allows probing of microscopic anisotropy in tissue, however, time-dependent diffusion (TDD) can bias results unless b-tensors are carefully tuned to account for TDD. We propose two novel strategies for tuning b-tensors to enable accurate measurements without interference from TDD due to restricted diffusion. The first strategy involves identifying encoding t
Disaster risk reduction (DRR) strategies must actively include people with disabilities (PWD) to ensure equitable and effective preparedness. Although awareness of disability inclusion in DRR is growing, the literature remains fragmented, and no prior structured literature review has focused specifically on participatory methods involving PWD. This review addresses that gap by identifying and synt
The central component of the complement cascade, C3, is involved in various biological functions, including opsonization of foreign bodies, clearance of waste material, activation of immune cells, and triggering of pathways controlling development. Given its broad role in immune responses, particularly in phagocytosis and the clearance of microbes, a deficiency in complement C3 in humans is often
Background Parathyroid surgery is an appropriate alternative for renal hyperparathyroidism (rHPT) in patients in whom medical therapy fails. European morbidity and outcome data for clearly defined cohorts, potentially reflecting contemporary clinical practice, remain scarce. Method Data were extracted from the EUROCRINE® database on all operations for secondary rHPT between 1 January 2015 and 31 D
A combination of searches for the single production of vectorlike top quarks ((Formula presented)) is presented. These analyses are based on proton-proton collisions at (Formula presented) recorded in 2015-2018 with the ATLAS detector at the Large Hadron Collider, corresponding to an integrated luminosity of (Formula presented). The (Formula presented) decay modes considered in this combination ar
High blood pressure (BP) is a frequent cause for visits to primary healthcare centers (PHCCs) in Sweden. Guidelines on methods for BP measurements for diagnosis of hypertension have recently been updated. We aimed to study adherence to diagnostic guidelines in hypertension management and evaluate whether adherence to guidelines was related to organizational or sociodemographic characteristics. Int
The humoral barrier in transplant biology is the result of preformed donor-specific antibodies (DSAs), directed either against human leukocyte antigens (HLA) or non-HLA antigens such as blood group (ABO) molecules. The term "sensitization" applies to patients carrying these antibodies. Transplantation is widely accepted as a life-saving opportunity for patients with terminal end-organ disease. How
Collective action by small-scale farmers can contribute significantly toward rural development. One important aspect that remains relatively neglected, especially in research set in Africa, is the role of farmer collectives in political processes. We study the local-level dynamics of a farmer-based organization mobilizing for agroecology and food sovereignty in Uganda. Through qualitative, collabo
Transcriptome-wide association studies (TWAS) are powerful tools for identifying gene-level associations by integrating genome-wide association studies and gene expression data. However, most TWAS methods focus on linear associations between genes and traits, ignoring the complex nonlinear relationships that may be present in biological systems. To address this limitation, we propose a novel frame
Virtual reality can be a useful research tool to investigate how people behave in different fire situations. For the results from such experiments to have good validity, i.e., to represent behaviours that can occur in a real environment, the VR environment must be perceived as a good substitute for the real environment. The project focuses on how to achieve such high-quality VR environments. Two d
Eosinophils are increasingly recognized as adaptable immune cells that exhibit diverse phenotypes and effector functions across different tissues and disease states. While they can induce pathology through degranulation and cytotoxic mediator release, eosinophils also fulfill regulatory and tissue repair roles. Advances in single-cell and spatial technologies have begun to reveal how microenvironm
