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Keeping Up Standards for a Better World : Anthropological Alternatives to the Study of International Organisations

In the post-World War II era, international lawyers have occupied the front seat in the study of international organisations (IOs). During the past decade, this disciplinary hierarchy has grown to feel increasingly unsatisfying. This chapter offers an anthropological take on the study of IOs building both on the past decade of anthropological work and my ethnography at the UN Human Rights Committe

Immune development differs between preterm newborns fed mothers’ own milk and donor milk

Extremely preterm infants are at risk of immune-mediated complications such as infections and inflammatory conditions like bronchopulmonary dysplasia and necrotizing enterocolitis. Preterm infants are immunologically distinct from term infants at birth, but subsequently undergo adaptive postnatal changes resulting in immunological convergence during their first 3 months. Here, we performed a syste

Equivalent fully coupled modeling and experimental validation of high-particle-concentration acoustofluidics

Acoustofluidic particle manipulation has attracted considerable interest in biomedical applications due to its non-contact and label-free characteristics. However, existing computational models for predicting particle motion in acoustofluidic systems mainly focus on single-particle behavior, often neglecting particle–particle interactions and the impact of particle distribution on the acoustic and

The multiple generator hypothesis of consciousness

It is well known that in interdisciplinary consciousness studies there are various competing hypotheses about the neural correlate(s) of consciousness (NCCs). Much contemporary work is dedicated to determining which of these hypotheses is right (or the weaker claim is to be preferred). The prevalent working assumption is that one of the competing hypotheses is correct, and the remaining hypotheses

Animal niches in the airspace

For flying animals, including many birds, bats, and insects, the air is a crucial arena for a range of behaviors. Technological advances, such as year-round tracking of flight altitudes and expanded use of radar, increasingly show how flying animals use the aerial habitat. This enables us to answer questions about the environmental patterns and ecological processes that shape aerial niches, includ

Latitude-specific responses of European birds' population growth rates to temperature and water availability

Climate limits distribution of species and shows considerable regional variability. However, studies relating climate variation to species population growth rates in different climatic zones while accounting for species' ecological traits are scarce. We assessed species population responses to the main climatic constraints at a continental scale by studying how precipitation and temperature at dif

Physical Activity, Arterial Stiffness, and Risk of Cardiovascular Disease and Death in Men and Women : A Population-Based Study

Physical activity lowers risk of cardiovascular disease and may also decrease arterial stiffness. We aimed to investigate whether arterial stiffness can explain part of the association between physical activity and the risk of major adverse cardiovascular events (MACE) and all-cause death in men and women. We followed 2583 individuals from the Malmö Diet and Cancer study (2007-2012) for occurrence

Structural Fire Behaviour

Fire safety and fire protection objectives require that buildings and parts of buildings do not collapse during a fire. This requires that the load-carrying capacity is maintained to a minimum acceptable level during a fire. This chapter briefly describes the historical background and state of the art of fire resistance and its determination for timber members through testing or calculations. The

Polygenic pathways shape white matter vulnerability to Alzheimer’s disease-related pathophysiological changes

Background: The accumulation of amyloid-β1−42 (Aβ1−42) peptides and phosphorylated-Tau181 (p-Tau181) tangles from the preclinical stages of Alzheimer’s disease (AD) has led to a biological definition of the disease. However, among Aβ1−42-positive individuals, cognitive decline onset varies, and some never develop symptoms. Genetic influences on molecular pathways and their interactions with protei

Arabidopsis phospholipid modifications mediate cellulase-induced resistance to a fungal peptide antibiotic by imposing cell polarity

Plant-symbiotic Trichoderma fungi attack microorganisms by secreting antibiotic membrane-permeabilising peptaibols such as alamethicin. These peptaibols also permeabilise plant root epidermis plasma membranes (PMs), but mild pretreatment with Trichoderma cellulase activates a unique cellulase-induced resistance to alamethicin (CIRA), via an unknown mechanism. We identify two Arabidopsis genes that

Machine learning-enhanced gas sensor technology identifies ovarian and endometrial cancer of all stages through plasma volatile organic compound patterns

Background: Ovarian cancer presents with non-specific symptoms that make early diagnosis challenging and the prognosis poor. Ovarian and endometrial cancers exhibit similar genomic mutations and biomarker profiles. Endogenous volatile organic compounds (VOCs) are products of metabolic activity. In cancer, metabolites increase due to tumour necrosis, leading to cancer-specific VOC patterns. The aim

How crystallization additives govern halide perovskite grain growth

The preparation of perovskite solar cells from the liquid phase is a cornerstone of their immense potential. However, a clear relationship between the precursor ink and the formation of the resulting perovskite is missing. Established theories, such as heterogeneous nucleation and lead complex colloid formation, often prove unreliable, which has led to an overreliance on heuristics. Most high-perf

Transcriptomic Profiling of Quinoa Reveals Distinct Defense Responses to Exogenous Methyl Jasmonate and Salicylic Acid

Plant defense responses are mediated by hormones such as jasmonic acid (JA) and salicylic acid (SA). JA and SA are known to trigger a range of different defense responses in model plants but little is described in crops like quinoa. Here, we present the first molecular description of JA and SA signaling at the transcriptomic level in quinoa. The transcriptomes of quinoa cv. Kurmi seedlings treated

Development policy affects coastal flood exposure in China more than sea-level rise

Effective coastal exposure assessments are crucial for adaptively managing threats from sea-level rise (SLR). Despite recent advances, global and regional assessments are constrained by omitting critical factors such as land-use change, failing to disaggregate potential impacts by land uses and oversimplifying land subsidence. Here we address these gaps by developing context-specific scenarios to

The cost-effectiveness of mild hypercapnia after out-of-hospital cardiac arrest : a health economic evaluation alongside the TAME study

Background: Out of hospital cardiac arrest (OHCA) is a significant public health problem associated with high mortality and high healthcare costs. The Targeted Therapeutic Mild Hypercapnia after Resuscitated Cardiac Arrest (TAME) randomised clinical trial showed that targeted mild hypercapnia did not lead to better neurologic outcomes at 6 months compared to normocapnia after OHCA. We aimed to est

AC_MAPPER : a robust approach to ATT&CK technique classification using input augmentation and class rebalancing

The detection and classification of adversarial techniques from cyber threat intelligence (CTI) text is a critical task in threat analysis and mitigation. While recent transformer-based models have shown promise, their general-purpose nature often limits effectiveness on complex, domain-specific datasets. In this paper, we present a novel model designed to address the challenges of technique class

Mitochondria-derived reactive oxygen species are the likely primary trigger of mitochondrial retrograde signaling in Arabidopsis

Besides their central function in respiration, plant mitochondria play a crucial role in maintaining cellular homeostasis during stress by providing "retrograde" feedback to the nucleus. Despite the growing understanding of this signaling network, the nature of the signals that initiate mitochondrial retrograde regulation (MRR) in plants remains unknown. Here, we investigated the dynamics and caus