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BACKGROUND: Both myocardial perfusion single-photon emission computed tomography (MPS) and exercise ECG (Ex-ECG) carry prognostic information in patients with stable chest pain. However, it is not fully understood if combining the findings of MPS and Ex-ECG improves risk prediction. Current guidelines no longer recommend Ex-ECG for diagnostic evaluation of chronic coronary syndrome, but Ex-ECG cou

We investigated the relationship between hs-CRP, a marker of low-grade inflam-mation, alone or in combination with C-peptide, a marker of hyperinsulinemia/ insulin resistance, and risk for cardiovascular events (CVEs) and mortality in patients recently diagnosed with type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS In patients with recent-onset T2D, we measured serum hs-CRP (n = 7,301) and C-pep

Hjärntumörer är en av de vanligaste barncancerdiagnoserna och många som överlever drabbas av sömnstörningar efteråt. Tumörens läge i hjärnan, tillsammans med vilken behandling man får, påverkar hur stor risken är. Det finns dock även andra faktorer som påverkar, och övervikt hos barnet är den enskilt största riskfaktorn för sömnsvårigheter.

The governance of public climate finance for mitigation and adaptation in developing countries is fragmented on both the international and national levels, with a high diversity of actors with overlapping mandates, preferences, and areas of expertise. In the absence of one unifying actor or institution, coordination among actors has emerged as a response to this fragmentation. In this article, we

The mammary gland is a dynamic organ with various physiological processes like cellular proliferation, differentiation, and apoptosis during the pregnancy-lactation-involution cycle. It is essential to understand the molecular changes during the lactogenic differentiation of mammary epithelial cells (MECs, the milk-synthesizing cells). The MECs are organized as luminal milk-secreting cells and bas

The guidelines provide specific recommendations based on published data or derived from expert consensus. Several analytes are found to have minimal clinical value at the present time, and measurement of them is not recommended.

Updated guidelines on the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) were released in 2021 by the American College of Rheumatology jointly with the Vasculitis Foundation and, subsequently, in 2022 by the European Alliance of Associations for Rheumatology. In addition, in 2021, the Kidney Disease: Improving Global Outcomes had released updated recommendatio

Due to renewable fuel mandates worldwide, the increase in biodiesel production has caused an oversupply of low-cost glycerol on the markets, which can negatively affect the sustainability of the biodiesel industry as a whole. In order to avoid that scenario, the transformation of glycerol into value-added products has been investigated, and the production of additives for internal combustion engin

Objective: The goals of this study were to assess the associations of severe nonadherence to hydroxychloroquine (HCQ), objectively assessed by HCQ serum levels, and risks of systemic lupus erythematosus (SLE) flares, damage, and mortality rates over five years of follow-up. Methods: The Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort is an international multicenter init

Background. Patients on kidney replacement therapy (KRT) have been identified as a vulnerable group during the coronavirus disease 2019 (COVID-19) pandemic. This study reports the outcomes of COVID-19 in KRT patients in Sweden, a country where patients on KRT were prioritized early in the vaccination campaign. Methods. Patients on KRT between January 2019 and December 2021 in the Swedish Renal Reg

Aim: Necrotising enterocolitis (NEC) is the dominating surgical emergency in preterm neonates. The aims were to investigate indications, surgical management and mortality for surgically treated neonates with NEC. Methods: Data were retrieved from the Swedish Neonatal Quality Register for Swedish neonates with surgically treated NEC from 1 January 2017 to 31 December 2021. Diagnosis was validated b

For individuals with symptomatic wrist osteoarthritis (OA), pain is the central problem negatively affecting all aspects of life. Despite the recommendations that all OA patients should be offered self-management treatment options, this approach is often lacking for patients with wrist OA. In addition, there has been surprisingly little interest shown in investigating wrist OA patients' wishes and

Since the eruption of the war in Ukraine in February 2022, both Ukrainian and Russian diasporas in Sweden have been reframing themselves through memories, narratives and symbols. They have been revised in connection to the initial Russian-backed insurgency in eastern Ukraine and the annexation of Crimea (2014), the “homeland” as well as previous diasporic mobilizations in the country of residence.

Background: In the last decades different preclinical animal models of Parkinson's disease (PD) have been generated, aiming to mimic the progressive neuronal loss of midbrain dopaminergic (DA) cells as well as motor and non-motor impairment. Among all the available models, AAV-based models of human alpha-synuclein (h-aSYN) overexpression are promising tools for investigation of disease progression

One of the classical multi-view geometry problems is the so called P3P problem, where the absolute pose of a calibrated camera is determined from three 2D-to-3D correspondences. Since these solvers form a critical component of many vision systems (e.g. in localization and Structure-from-Motion), there have been significant effort in developing faster and more stable algorithms. While the current s

We present novel solutions to previously unsolved prob-lems of relative pose estimation from images whose calibration parameters, namely focal lengths and radial distortion, are unknown. Our approach enables metric reconstruction without modeling these parameters. The minimal case for reconstruction requires 13 points in 4 views for both the calibrated and uncalibrated cameras. We describe and imp

Finding the right coatings for cutting tools is essential in order to increase the tool wear resistance and, thus, to get better surface roughness for the machined workpieces, and to improve productivity. A coating requirements are not only its mechanical and strength properties, but also its response to a given load and a given wear exposure. To expand ideas about the phenomena and mechanisms of

By replacing conventional gray cast iron (GI) with compacted graphite iron (CGI), automotive industry could keep up with stricter regulations on emissions and demands on higher engine performance. CGI has improved properties as to GI but is more difficult to machine. This study evaluates sustainable machining performance during finish face milling when using minimum quantity lubrication applied ve