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Involvement of glutamate neurotransmission in the development of excessive wheel running in Lewis rats

Physical activities such as long-distance running can form a habit and might be related to drug-induced addictive behaviors. We investigated possible modulations of N-methyl-D-aspartate (NMDA) receptor subunits during voluntary wheel running in brain regions implicated in reward and addiction. It was observed that Lewis rats progressively increased their amount of daily running, reaching maximum l

Effects of Tolterodine on Afferent Neurotransmission in Normal and Resiniferatoxin Treated Conscious Rats.

Purpose: The beneficial effects of antimuscarinics on detrusor overactivity and overactive bladder syndrome are exerted during bladder filling, when there is no parasympathetic outflow from the spinal cord. We tested the hypothesis that, if tolterodine exerts some of its effects on afferent nerves, the functional elimination of C-fiber afferents should affect the actions of the drug on urodynamic

A systematic overview of radiation therapy effects in soft tissue sarcomas

A systematic review of radiation therapy trials in several tumour types was performed by The Swedish Council of Technology Assessment in Health Care (SBU). The procedures for evaluation of the scientific literature are described separately (Acta Oncol 2003; 42: 357-365). This synthesis of the literature on radiation therapy for soft tissue sarcomas (STS) is based on data from five randomized trial

Förändringar i utbredningsbilden hos Parmelia elegantula och Parmelia laciniatula i Skåne och Blekinge.

The Swedish localities for Parmelia eleganrula (Zahlbr.) Szat. and Parmelia laciniatula (Oliv.) Zahlbr.wers outlined in denil by Almborn (1948) in a work on the distribution and ecology of some south Scandinavian lichens. In the summer of 1987, I revisited Ahnborn's renumerated localities in Sklne and Blekinge. Several new localiries were also registrated. Both species, as prcsumed, turned out to

Influence of bondline brittleness and defects on the strength of timber finger-joints

Numerical finite element results on the mechanical behaviour of finger-joints for laminated timber products are presented. Simulations are based on a nonlinear fracture mechanics description of the bondlines in the finger-joints. It is shown that, for a commonly used resorcinol–phenol adhesive, there is potential of increasing substantially the finger-joint strength by increasing the fracture ener

Effect of low molecular weight heparin, dextran and their combinations on experimental venous thrombosis in rabbits

An experimental model based on the combination of endothelial damage and flow reduction was used to induce jugular vein thrombosis in rabbits. The effect on thrombosis of a low molecular weight heparin (LMWH [Fragmin]), dextran 70, placebo and their combination was studied in a double-blind fashion with actual doses used in clinical thromboprophylaxis. Saline and polygeline were used as placebo in

Effects of hypertonic saline, mannitol, and urea with regard to absorption and rebound filtration in cat skeletal muscle.

OBJECTIVE: To study the effects of the hypertonic solutions 15% mannitol, 3% and 7.5% saline, and 30% urea at clinically relevant plasma concentrations with regard to absorption and rebound effects on tissue volume in skeletal muscle. DESIGN: A prospective, experimental study. SETTING: University laboratory. SUBJECTS: Twenty-eight anesthetized cats. INTERVENTIONS: The study was performed on an aut

A 1-year follow-up quality of life study after hemodynamically successful or unsuccessful surgical revascularization of lower limb ischemia

PURPOSE: The impact of hemodynamically successful or unsuccessful bypass grafting or angioplasty on patients' quality of life was assessed throughout the first year postsurgery. METHODS: A total of 146 patients, 97 patients who underwent successful revascularization and 49 patients who underwent unsuccessful revascularization, were assessed for quality of life with the Nottingham Health Profile. R

External rotation stress imaging in syndesmotic injuries of the ankle - Comparison of lateral radiography and radiostereometry in a cadaveric model

We compared the value of 7.5 Nm external rotation stress in diagnosing tibiofibular syndesmotic injuries of the ankle on lateral radiographs with radiostereometric analysis (RSA) in 10 cadaveric legs. After sectioning 2 ligaments, RSA showed an increase in posterior translation and external rotation of the fibula. This increase in posterior translation was smaller than the posterior displacement o

Evolution of parasitism in nematode-trapping fungi

We are studying the evolution of parasitism in a group of soil-living ascomycetes that can grow as saprophytes as well as parasites by forming special morphological structures called traps. Analyses of 18S ribosomal DNA sequences have shown that these fungi form a monophyletic and isolated clade among the ascomycetes. The phylogenetic patterns within this clade are concordant with the morphology o

Characterization of a computer board-to-board ultra-wideband channel

In this paper we present the results of an extensive ultra-wideband (UWB) measurement campaign performed inside the chassis of two desktop computers. The purpose of the campaign is to analyze the possibility of board-to-board communications, replacing cable connections. Measurements of the propagation channel are performed over a frequency range of 3.1 - 10.6 GHz using a vector network analyzer an

Performance analysis of general charge sampling

This brief focuses on the performance analysis of general charge-sampling circuits for signal capture. The theoretical analysis in the brief can be applied not only for weak signal capture, but also for the normal signal sampling. Based on a general charge-sampling model, the transfer function, the noise performance, and the clock jitter tolerance are analyzed and compared to conventional voltage