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Existence and exponential decay of solutions to a quasilinear thermoelastic plate system

We consider a quasilinear PDE system which models nonlinear vibrations of a thermoelastic plate defined on a bounded domain in R^n, n ≤ 3. Existence of finite energy solutions describing the dynamics of a nonlinear thermoelastic plate is established. In addition asymptotic long time behavior of weak solutions is discussed. It is shown that finite energy solutions decay exponentially to zero with t

Perturbations of embedded eigenvalues for the bilaplacian on a cylinder

Perturbation problems for operators with embedded eigenvalues are generally challenging since the embedded eigenvalues cannot be separated from the rest of the spectrum. In this paper we study a perturbation problem for embedded eigenvalues for the bilaplacian with an added potential, when the underlying domain is a cylinder. We show that the set of nearby potentials, for which a simple embedded e

Reinforcement learning for visual object detection

One of the most widely used strategies for visual object detection is based on exhaustive spatial hypothesis search. While methods like sliding windows have been successful and effective for many years, they are still brute-force, independent of the image content and the visual category being searched. In this paper we present principled sequential models that accumulate evidence collected at a sm

Novel microRNA regulators of atrial natriuretic peptide production

Atrial natriuretic peptide (ANP) has a central role in regulating blood pressure in humans. Recently, microRNA 425 (miR-425) was found to regulate ANP production by binding to the mRNA of NPPA, the gene encoding ANP. mRNAs typically contain multiple predicted microRNA (miRNA)-binding sites, and binding of different miRNAs may independently or coordinately regulate the expression of any given mRNA.

Does the recording medium influence phonetic transcription of cleft palate speech?

Background: In recent years, analyses of cleft palate speech based on phonetic transcriptions have become common. However, the results vary considerably among different studies. It cannot be excluded that differences in assessment methodology, including the recording medium, influence the results. Aims: To compare phonetic transcriptions from audio and audio/video recordings of cleft palate speech

Micelle structure in a deep eutectic solvent : A small-angle scattering study

In recent years many studies into green solvents have been undertaken and deep eutectic solvents (DES) have emerged as sustainable and green alternatives to conventional solvents since they may be formed from cheap non-toxic organic precursors. In this study we examine amphiphile behaviour in these novel media to test our understanding of amphiphile self-assembly within environments that have an i

Multidimensional customer requirements acquisition based on ontology

To acquire the demand information comprehensively and facilitate demand information reuse, the research of acquisition and expression of user requirements were carried on based on user's cognitive process, ontology and development law of requirements. According to the expression and existing condition of user requirements, the acquisition strategy based on requirements classification was proposed.

Neutrophil Protease Cleavage of Von Willebrand Factor in Glomeruli - An Anti-thrombotic Mechanism in the Kidney

Adequate cleavage of von Willebrand factor (VWF) prevents formation of thrombi. ADAMTS13 is the main VWF-cleaving protease and its deficiency results in development of thrombotic microangiopathy. Besides ADAMTS13 other proteases may also possess VWF-cleaving activity, but their physiological importance in preventing thrombus formation is unknown. This study investigated if, and which, proteases co

Complement contributes to the pathogenesis of Shiga toxin-associated hemolytic uremic syndrome

Complement is activated during Shiga toxin-producing Escherichia coli-associated hemolytic uremic syndrome (STEC-HUS). There is evidence of complement activation via the alternative pathway in STEC-HUS patients as well as from in vivo and in vitro models. Ozaki et al. demonstrate activation of the mannose-binding lectin (MBL) pathway in Shiga toxin-treated mice expressing human MBL2, but lacking m

Enterohemorrhagic Escherichia coli Pathogenesis and the Host Response

Enterohemorrhagic Escherichia coli (EHEC) is a highly pathogenic bacterial strain capable of causing watery or bloody diarrhea, the latter termed hemorrhagic colitis, and hemolytic-uremic syndrome (HUS). HUS is defined as the simultaneous development of non-immune hemolytic anemia, thrombocytopenia, and acute renal failure. The mechanism by which EHEC bacteria colonize and cause severe colitis, fo

Shiga toxin pathogenesis : kidney complications and renal failure

The kidneys are the major organs affected in diarrhea-associated hemolytic uremic syndrome (D(+)HUS). The pathophysiology of renal disease in D(+)HUS is largely the result of the interaction between bacterial virulence factors such as Shiga toxin and lipopolysaccharide and host cells in the kidney and in the blood circulation. This chapter describes in detail the current knowledge of how these bac

Clouding of nonionic surfactants

Nonionic surfactants have broad applications such as cleaning and dispersion stabilization, which frequently are hampered by strong temperature sensitivities. As manifested by clouding and decreased solubility with increasing temperature, the interaction between water and the oligo(oxyethylene) head-groups is becoming less favorable. Different aspects of surfactant self-assembly, like the critical