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Urban areas are increasingly exposed to extreme precipitation events, which can disrupt critical infrastructure and damage the built environment. While flood impacts are often assessed separately for buildings or road networks, this study analyses both flood-induced road inaccessibility and building flood risk in Gothenburg using a climate-adjusted 100-year rainfall at both the city scale and the
Lung transplantation (LTx) remains the only curative treatment for patients with end-stage lung disease, yet long-term outcomes remain inferior to those of other solid organ transplantations, with a 5-year survival below 70%. Major contributors to this limited outcome include primary graft dysfunction (PGD), the leading cause of early mortality, chronic lung allograft dysfunction (CLAD), and low u
Based on ten months of research at an elite university in Beijing (Qinghua University) this article focuses on the conundrums of life for young people in China today. It addresses the paradoxical situation faced by many young people, who are among the lucky few, who have made it to the top of a very competitive educational system yet feel deeply ambivalent about their own futures. Through a detail
This article is based on anthropological fieldwork undertaken at two elite universities in Beijing. It addresses the paradoxical situation of the many instances of suicide among Chinese elite university students in Beijing, which constitute a public secret. The pressure of education weighs heavily on the shoulders of China’s only child in each family, known as the generation of little emperors and
Malaria caused by Plasmodium falciparum (P. falciparum) remains a major cause of morbidity and mortality, particularly in sub-Saharan Africa. Immunity develops gradually after repeated exposure and is largely mediated by antibodies, yet the mechanisms regulating the development and function of humoral immunity, including the roles of B-cell subsets and inflammatory mediators, remain incompletely u
Opioider, som är ett narkotiskt läkemedel med mycket effektivt smärtlindrande effekt vid akuta smärttillstånd och i samband med smärtsamma ingrepp i dagens sjukvård. Under många år har opioider också använts för att behandla långvarig smärta som inte beror på cancer. Det finns risker med en sådan behandling då den kan leda till beroende och överdos. Samtidigt saknas bevis för att opioider lindrar
Siden starten af det 20. århundrede har Shanghai haft status som Kinas mest vestliggjorte by. På grund af Shanghais placering som Kinas vigtigste havneby og indgangsport til Kina for den øvrige verden har byen været hjemsted for den handelsmæssige og den intellektuelle elite
Background: This is one of the few European studies of self-management and self-monitoring during the initial two weeks following discharge after open cardiac surgery. Typical outcomes are mortality, morbidity, surgical complications and additional medical treatment. Equally important for enabling person-centred care are the patients’ perspective and main concerns. The aim was to explore feasibili
Förbättring av Krämer för Fotodynamisk Behandling av Hudcancer Fotodynamisk terapi (PDT) är en modern och relativt skonsam behandlingsmetod som används vid vissa typer av hudcancer och förstadier till hudcancer. I stället för att operera bort vävnad används ett ljuskänsligt läkemedel som appliceras på huden. När det behandlade området belyses med ljus av en specifik våglängd reagerar läkemedlet mePhotodynamic therapy (PDT) is an established treatment for actinic keratosis and selected non-melanoma skin cancers. Still, its broader use is limited by pain, skin irritation, and formulation constraints associated with high photosensitiser concentrations. This study aimed to develop and evaluate a Crystalip®-based topical PDT formulation that enables two-step manufacturing, delivers methyl-amino
Hur processparametrar kontrollerar partikelstorlek vid mikronisering Mediciner avsedda att inhaleras behöver bestå av väldigt små partiklar för att de effek-ivt ska kunna nå och absorberas av lungorna. Produktion av dessa partiklar kan vara komplex och små ändringar i processparametrar kan leda till stora ändringar i hur effektivt medicinen levereras till lungorna. Detta projekt undersöker en ekvMicronization is a key process in the pharmaceutical industry, particularly in the production of inhalable particles which have to be in the size range of 1-5 µm. Particle size reduction in a spiral jet mill is a complex process which has been investigated theoretically and empirically resulting in complex equations. In this project a simple equation for describing micronization energy (Eµ) and a
We study the effect of more informative feedback on student performance. Using data on the population of Swedish school children, we exploit a reform to the grading system in compulsory school which in 2011 introduced a more granular grading scale and thus provided students with more informative feedback on their academic performance. Exploiting a difference-in-discontinuity research design, we fi
