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Din sökning på "global studies" gav 21853 sökträffar
Recording Patient Data in Burn Unit Logbooks in Rwanda : Who and What Are We Missing?
Systematic data collection in high-income countries has demonstrated a decreasing burn morbidity and mortality, whereas lack of data from low- and middle-income countries hinders a global overview of burn epidemiology. In low- and middle-income countries, dedicated burn registries are few. Instead, burn data are often recorded in logbooks or as one variable in trauma registries, where incomplete o
'You need to be healthy to be sick' : Exploring older people's experiences with medication packaging at home
Background: the ageing global population is living longer with complex health conditions addressed by multiple medications. Little is known about how older people manage these medications and associated packaging at home. Objectives: to explore how older people manage the use of multiple medication and associated packaging in their process of self-care. Methods: fifteen older, home-dwelling partic
Genetics and epigenetics of liver cancer
Hepatocellular carcinoma (HCC) represents a major form of primary liver cancer in adults. Chronic infections with hepatitis B (HBV) and C (HCV) viruses and alcohol abuse are the major factors leading to HCC. This deadly cancer affects more than 500,000 people worldwide and it is quite resistant to conventional chemo- and radiotherapy. Genetic and epigenetic studies on HCC may help to understand be
Current water quality guidelines across North America and Europe do not protect lakes from salinization
Human-induced salinization caused by the use of road deicing salts, agricultural practices, mining operations, and climate change is a major threat to the biodiversity and functioning of freshwater ecosystems. Yet, it is unclear if freshwater ecosystems are protected from salinization by current water quality guidelines. Leveraging an experimental network of land-based and in-lake mesocosms across
Internet Use and Loneliness Among Older Adults : The Moderating Role of Self-perceptions of Ageing
Loneliness in advanced age has become one of the societal concerns considering its detrimental effects on physical and mental health of older people. Information and communication technologies show the potential to prevent or tackle loneliness and social isolation among older people. Given a percentage of the older population feeling lonely, loneliness in older age has been increasingly recognized
Underlying Differences in Health Spending Within the World Health Organisation Europe Region-Comparing EU15, EU Post-2004, CIS, EU Candidate, and CARINFONET Countries
This study examined the differences in health spending within the World Health Organization (WHO) Europe region by comparing the EU15, the EU post-2004, CIS, EU Candidate and CARINFONET countries. The WHO European Region (53 countries) has been divided into the following sub-groups: EU15, EU post-2004, CIS, EU Candidate countries and CARINFONET countries. The study period, based on the availabilit
Second-hand values and the production of ethical urban markets
We are seeing today an increased interest in ethics, the environment, and social responsibility at the same time as the individual is expected, in different ways, to realize him-/herself through consumption. These interests coincide with the establishment of ethical markets for re-use and second-hand. In this paper we investigate and map out the ethical shopping spaces in Helsingborg, and how thes
Comparison of transcriptional changes to chloroplast and mitochondrial perturbations reveals common and specific responses in Arabidopsis
Throughout the life of a plant, the biogenesis and fine-tuning of energy organelles is essential both under normal growth and stress conditions. Communication from organelle to nucleus is essential to adapt gene regulation and protein synthesis specifically to the current needs of the plant. This organelle-to-nuclear communication is termed retrograde signaling and has been studied extensively ove
Time-Dependent pH Scanning of the Acid-Induced Unfolding of Human Serum Albumin Reveals Stabilization of the Native Form by Palmitic Acid Binding
The most abundant plasma protein, human serum albumin (HSA), is known to undergo several conformational transitions in an acidic environment. To avoid buffer effects and correlate global and local structural changes, we developed a continuous acidification method and simultaneously monitored the protein changes by both small-angle scattering (SAXS) and fluorescence. The progressive acidification,
Identifying predictors of within-person variance in MRI-based brain volume estimates
Adequate reliability of measurement is a precondition for investigating individual differences and age-related changes in brain structure. One approach to improve reliability is to identify and control for variables that are predictive of within-person variance. To this end, we applied both classical statistical methods and machine-learning-inspired approaches to structural magnetic resonance imag
Modifying Natural Zeolites to Improve Heavy Metal Adsorption
Problems with increasing heavy metal contents in natural waters are becoming a global issue. At the same time, improved methods for water treatment are becoming increasingly important. In this context, natural zeolites can be used to purify polluted water. In this paper, we investigated how the adsorption capacity of natural zeolites can be improved. Natural zeolites from the Shankanay district, A
Beliefs about medications when treating hypertension in primary health care : results from "PERson-centredness in hypertension management using information Technology (PERHIT)"
The most important theoretical developments leading to the current understanding of heavy-element stability : With some personal recollections from the past 55 years (1965–2020)
We discuss the sequence of developments that over the past 90 years led to current insights on heavy-element stability. The semi-empirical mass model, and its extension to deformed shapes, developed in the period 1936–1950 allowed the interpretation of nuclear fission. Around 1950 the spherical single-particle model was developed, soon after with extension to deformed nuclei. Speculations about a
Capturing the Kidney Transcriptome by Urinary Extracellular Vesicles—From Pre-Analytical Obstacles to Biomarker Research
Urinary extracellular vesicles (uEV) hold non-invasive RNA biomarkers for genitourinary tract diseases. However, missing knowledge about reference genes and effects of preanalytical choices hinder biomarker studies. We aimed to assess how preanalytical variables (urine storage temperature, isolation workflow) affect diabetic kidney disease (DKD)—linked miRNAs or kidney—linked miRNAs and mRNAs (kid
Perspectives on agroecological transition: the case of Guachetá municipality, Colombia
Regional sea-surface temperatures explain spatial and temporal variation of summer precipitation in the source region of the Yellow River
Risk Assessments of Natural Hazards in Refugee Camp Planning in Greece. Challenges and Recommended Actions.
The rapid increase of asylum-seekers in 2015 overwhelmed the Greek reception system and led to the creation of numerous refugee camps throughout the country. The Sphere Minimum Standards provide globally acknowledged guidance to design and manage these facilities. They designate risk assessments as an essential tool to guarantee a safe environment for Persons of Concern. Yet, exposure to natural h
Coloniality in Intellectual Property Rights Legitimations: A Critical Discourse Analysis of The Pharmaceutical Industry’s Legitimation of Intellectual Property Rights During the COVID-19 Pandemic
The COVID-19 pandemic sparked a global debate on intellectual property rights involving various actors including nation states, civil society, and business. In October 2020, South Africa and India proposed that certain intellectual property rights on COVID-19 health products should be temporarily waivered for the remainder of the pandemic invoking strong opposition from the pharmaceutical industry
Understanding Supply Chain Visibility Through Experts’ Perspective : A Delphi Based Approach
Visibility in production logistics and across the supply chain has become a key concern for organizations. Its need has been further emphasized due to the current COVID 19 crisis. Organizations find it challenging to prepare the internal logistics and supply chain, and quickly respond to such unexpected events, due to low visibility. Against this backdrop, the paper, which is a work-in-progress, s
