Due to the global demographic change many more people will need to work until anolder age, and organisations and enterprises need to implement measures to facilitate an extendedworking life. The aim of this study was to investigate organisational measures and suggestionsto promote and make improvements for a healthy and sustainable working life for all ages in anextended working life. This is a qu

IntroductionDementia remains incurable, and treatment trials are typically conducted after the symptoms manifest, potentially too late in the disease process to alter its course. Early identification and intervention during the pre-diagnosis phase offer the potential to introduce more cost-effective strategies and enhance quality of life. This review aims to scrutinise emerging evidence and presen

Män med utländsk bakgrund har en kraftig överrepresentation vad gäller våldtäkter. Ny forskning visar att integration har betydelse. Men socioekonomi har mindre betydelse, skriver läkaren och forskaren Ardavan Khoshnood.Men with a foreign background are significantly overrepresented when it comes to rape. New research shows that integration plays an important role, while socio-economic status has less significance, writes physician and researcher Ardavan Khoshnood.

INTRODUCTION: Mental health service users often have sensory processing difficulties hampering their ability to cope with mental health problems and occupational engagement. However, there is little knowledge of sensory processing and its relation to these factors. Hence, this current study aims to investigate sensory processing patterns in relation to coping and occupational engagement for the ta

The name Huea, used for a lichen genus which hosts the two common Antarctic species H. cerussata and H. grisea (= H. coralligera), was formally recommended for rejection by the Nomenclature Committee for Fungi. Based on molecular data, we transfer these two species to the genus Hueidea. Hueidea was originally described in the family Fuscideaceae for the single alpine Australian endemic species Hue

This open access book examines the long-term impact of Christian missionaries in Zambia, and sub-Saharan Africa more generally, on education, health, and economic development. It examines how Christian missionaries provided Western-style education and healthcare within sub-Saharan Africa during the 20th century and how this was provided along unequal gender and regional lines. With sub-Saharan Afr

This paper aims to show how systems thinking can be used to investigate barriers to organisational change management. The case study described in this paper would be useful to managers who want to implement change in their own organisations. Soft Systems Methodology and ETHICS were used due to their flexible, responsive, and emergent nature. Also, soft systems methodology (SSM) and ETHICS (Effecti

Abstract in FrenchLa superstition et la pensée magique sont omniprésentes dans le football, quel que soit le contexte culturel. Afin de mieux comprendre le lien étroit entre ce jeu et les croyances irrationnelles, l’article mobilise, en partant de l’analyse de quelques confessions de fans superstitieux, les réponses fournies par l’anthropologie, la philosophie de l’absurde, et la sociologie des reSuperstition and magical thinking are omnipresent in football, whatever the cultural context. In order to gain a better understanding the origin of the irrational beliefs that seem closely linked to the game, starting with some confessions of superstitious fans, the article draws on the tentative responses provided by anthropology, the philosophy of absurdism, and the sociology of religion. It con

Soloviolin: Anne Sophie Andersen. Förlag: Svensk musik

This thesis aims to deepen the knowledge of physical stability and aggregation of proteins by studying two proteins under combinations of stress factors such as heat, pumping, and seeding. The work addressed questions such as how combinations of techniques can be used to study aggregation pathways, how the formulation might affect the formation of micron-sized particles during pumping, and finally

Background: Clinical trials have provided evidence that transplants of dopaminergic precursors, which may be replaced by new in vitro stem cell sources, can integrate into the host tissue, and alleviate motor symptoms in Parkinson´s disease (PD). In some patients, deterioration of graft function occurred several months after observing a graft-derived functional improvement. Rejection of peripheral

Parkinson's disease is a neurodegenerative condition characterized by motor impairments caused by the selective loss of dopaminergic neurons in the substantia nigra. Levodopa is an effective and well-Tolerated dopamine replacement agent. However, levodopa provides only symptomatic improvements, without affecting the underlying pathology, and is associated with side effects after long-Term use. Cel

There are sex differences in microglia, which can maintain sex-related gene expression and functional differences in the absence of circulating sex steroids. The angiotensin type 2 (AT2) receptors mediate anti-inflammatory actions in different tissues, including brain. In mice, we performed RT-PCR analysis of microglia isolated from adult brains and RNA scope in situ hybridization from males, fema

Mesenchymal stromal cells (MSCs) have been shown to have useful properties for cell therapy and have been proposed for treatment of neurodegenerative diseases, including Parkinson’s disease. However, the mechanisms involved in recovering dopaminergic neurons are not clear. The present study aims to evaluate the pathways and molecules involved in the neuroprotective effect of MSCs. We analyzed the

BACKGROUND: School principals face a demanding work situation that puts them at risk for stress-related poor mental health. Ideally, preventive actions should be based on knowledge about the underlying notions that motivate action. However, knowledge about prevention areas and suitable initiatives for school principals is scarce or lacking, leaving key stakeholders without the overview necessary f

Reactive oxygen species (ROS) are signalling molecules used to regulate cellular metabolism and homeostasis. However, excessive ROS production causes oxidative stress, one of the main mechanisms associated with the origin and progression of neurodegenerative disorders such as Parkinson’s disease. NRF2 (Nuclear Factor-Erythroid 2 Like 2) is a transcription factor that or-chestrates the cellular res

Adult neurogenesis is a dynamic and highly regulated process, and different studies suggest that dopamine modulates ventricular-subventricular zone (V-SVZ) neurogenesis. However, the specific role of dopamine and the mechanisms/factors underlying its effects on physiological and pathological conditions such as Parkinson's disease (PD) are not fully understood. Recent studies have described counter

Groupa started the new project 'Kind of Folk VOL 5 - Poland'. A collaboration with polish musicians: Grzech Piotrowski - sax, Marta Matuszna - vocalsThis day there was a concert at the Skansen museum nearby Olsztyn.