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Comparison of sprinkler activation times under flat and corrugated metal deck ceiling

The distance of sprinklers below ceiling is of fundamental importance since it has a great influence on activation time. Accepted distances are specified in different sprinkler standards such as NFPA 13, FM 2-0 and EN 12845 for different configurations. This distance is unambiguously defined for flat smooth ceilings, but for corrugated ceilings, such as corrugated metal deck ceilings found in many

Estrogen and progesterone receptor analyses in more than 4000 human breast cancer samples : A study with special reference to age at diagnosis and stability of analyses

Estrogen (ER) and progesterone receptors (PgR) were measured in the same laboratory in more than 4000 breast cancer biopsy samples obtained from 15 different hospitals during ten years. ER was measured with isoelectric focusing and PgR with the dextran-coated charcoal method and Scatchard analysis. The distribution pattern for both ER and PgR was during this time period and for the different hospi

Heat release and flame spread assessment of insulation in External Thermal Insulation Composite System (ETICS) facades

External Thermal Insulation Composite Systems (ETICS) represent a popular modern facade for reducing energy consumption, particularly in retrofit applications. Insulation - typically in the form of either EPS (expanded polystyrene) or mineral wool - is applied to the exterior of buildings using mortar adhesive, and then coated with a final layer of sand-cement render and glass fibre reinforcement.

Alternative Fuels for Particulate Control in CI Engines

It is widely known that diesel combustion in a compression ignition (CI) engine produces and emits a significant amount of particulate matter (PM) which contributes to degradation in both health and environment. The origin of the soot formation depends on several factors, however, the main source of the soot emissions is the combustion of the diesel fuel itself. To circumvent this issue, studies hIt is widely known that diesel combustion in a compression ignition (CI) engine produces and emits a significant amount of particulate matter (PM) which contributes to degradation in both health and environment. The origin of the soot formation depends on several factors, however, the main source of the soot emissions is the combustion of the diesel fuel itself. To circumvent this issue, studies h

Unifying first-principles and model approaches for strongly correlated materials : Interplay between long- and short-range correlations

Fysik handlar om att försöka förstå hur världen omkring oss fungerar utifrån vissa grundläggande principer. Fasta tillståndets fysik fokuserar på de fasta material vi har omkring oss. Dessa material har olika strukturer beroende på vilka grundämnen de är uppbyggda av och hur de har bildats. Om en gas av atomer kyls ner långsamt tenderar atomerna att ordna sig i specifika regelbundna mönster, så kaIn materials with open 3$d$ and 4$f$ shells the valence electrons are relatively localized around the atoms which leads to large electron-electron correlations. These, so called strongly correlated materials, exhibit many intriguing properties such as high $T_c$ superconductivity, colossal magneto-resistance and heavy fermion behaviour. The strong electron-electron correlations make these material

Association of int2/hst1 coamplification in primary breast cancer with hormone-dependent phenotype and poor prognosis

The human proto-oncogene INT2 (homologous to the mouse INT2 gene, implicated in proviral induced mammary carcinoma) has been mapped to chromosome llql3 and found to share band localisation with, among others, the HST1 proto-oncogene. Both genes are members of the fibroblast growth factor family. In the present study, coamplification (2-15 copies) of the INT2/HST1 genes was found in 27 (9%) of 311

DNA ploidy assessment of breast milk (colostrum) in primiparous women of different ages

Recent studies on breast cancer risk factors suggest that nursing may have a protective effect. The mechanism behind this is unknown. To investigate whether removal of tumorigenic epithelial cells in breast milk contributes to the reduced risk of developing breast cancer, DNA ploidy of cells in colostrum breast milk from 200 primiparous women was studied with flow cytometry. No woman displayed an

HER-2/neu and INT2 proto-oncogene amplification in malignant breast tumors in relation to reproductive factors and exposure to exogenous hormones

In previous studies in southern Sweden, early use of oral contraceptives has been found to be accompanied by an increased risk of developing premenopausal breast cancer, and the tumors developing in these patients have shown a more aggressive behavior. In the present study, amplification of the proto-oncogenes Her-2/neu (also known as ERBB2) and INT2 was studied in primary tumor specimens from 72

Survival in breast cancer and age at start of oral contraceptive usage

In general, findings in studies on oral contraceptives (OCs) and breast cancer have not indicated prognosis to be worse among users of OCs. In few studies, however, has age at the start of OC usage been considered as a prognostic factor. In the present study prognosis in breast cancer is compared with OC usage particularly with age at the start of OC usage among 193 consecutive patients at the Dep

Early oral contraceptive use and premenopausal breast cancer--a review of studies performed in southern Sweden.

In southern Sweden, extensive oral contraceptive use (OC use) among young women was a reality during the 1960s, thus making our region especially suited for studies investigating the hypothesis that early OC use is associated with the development of premenopausal breast cancer after a possible latency time between the exposure and the disease. The results of this study revealed that the risk of de

Neuroendocrine differentiation in male breast carcinomas

The presence of neuroendocrine differentiation, as expressed by cellular chromogranin immunoreactivity, was investigated in paraffin‐embedded tissue material from 51 consecutive cases of male breast carcinoma. From six of these cases electron microscopic studies were included. Chromogranin‐immunoreactive cells were present in solid cords and delineated tubular structures. Ultrastructurally, dense

Chromosome I alterations in breast cancer : Allelic loss on Ip and Iq Is related to lymphogenic metastases and poor prognosis

The development of human breast cancer is characterized by a variety of genetic alterations, and cytogenetic analyses have documented the consistent involvement of both arms of chromosome I. In the present study, molecular markers detecting restriction fragment length polymorphisms were used in pairwise screening of normal and tumor DNA to determine the frequency of allelic imbalance in breast tum

Anxiety and depression in breast cancer patients at start of adjuvant radiotherapy : Relations to age and type of surgery

Using a self-report questionnaire, the Hospital Anxiety and Depression (HAD) scale, feelings of anxiety and depression were assessed in 133 breast cancer patients referred for adjuvant radiotherapy following surgical treatment. Eighteen patients (14% had scores indicating morbid anxiety. Significant depression was recorded for only 2 patients (1.5% Severe anxiety was recorded for 10 out of 54 mast

Southern travelling habits with special reference to tumour site in Swedish melanoma patients

Southern travelling habits were recorded for 127 melanoma patients from southern parts of Sweden (the 56th latitude), 55 thyroid cancer patients, 100 non-Hodgkin's patients and 794 healthy controls from the same region. Melanoma patients were found to travel significantly more often south of the 45th latitude, as compared with patients with non-Hodgkin's lymphoma or thyroid carcinoma (RR = 2.2 for

The Retinoblastoma Gene in Breast Cancer : Allele Loss Is Not Correlated with Loss of Gene Protein Expression

The significance of the retinoblastoma gene (RB) in the development of human breast cancer remains unclear. In the present study, loss of heterozygosity (LOH) in RB was found in 26% of 90 informative primary breast tumors and was correlated to DNA nondiploidy, a high S-phase fraction, and LOH at chromosome 17pl33. However, allele loss was not associated with loss of RB protein (pRB) expression. Lo