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Type 2 or non-insulin-dependent diabetes mellitus (NIDDM) is the most common form of diabetes worldwide, affecting approximately 4% of the world's adult population. It is multifactorial in origin with both genetic and environmental factors contributing to its development. A genome-wide screen for type 2 diabetes genes carried out in Mexican Americans localized a susceptibility gene, designated NID
This thesis is an investigation of the potential of holographic laser interferometry for the study of diffusion of both small solutes and macromolecules. An investigation on the importance of errors due to light deflection in refarctive index gradients showed that the magnitude of the refractive index gradients were negligible for the system investigated. The holographic interferometry technique r
Dissemination of risk information is ubiquitous in contemporary society. We explore how individuals react in everyday life to health-risk information, based on what they report in personal interviews. Health-risk information was without exception recognized as unstable and inconsistent. This conformity, however, did not extend to the narratives regarding how health-risk information should be handl
We investigate the interplay between electronic and nuclear relaxation of the core-excited NO3 anion in solid LiNO3 and NaNO3 by means of the high-resolution X-ray absorption and resonant Auger spectroscopy. It is shown how the relative energy distances between the potential energy surfaces of the intermediate and final states can be mapped using the information on the dispersion of individual par
Glycobiology is the world of sugars: how they are made, what they look like, and what they do. Despite the importance of glycan structures in life, knowledge has been hampered due to their inherent complexity. Lectins are nature's way to decipher the intricate code held by glycans, which makes them important players in both normal and pathological physiology. A key to the understanding of lectins
We present a parameter-free model that estimates the density of excitons in Cu2O, related to experiments that have tried to create an excitonic Bose-Einstein condensate. Our study demonstrates that the triplet-state excitons move along adiabats and obey classical statistics, while the singlet-state excitons are a possible candidate for forming a Bose-Einstein condensate. Finally we show that the r
BACKGROUND: Acute pancreatitis (AP) results in elevated concentrations of trypsinogen (T) isoenzymes in serum. Immunoreactive anionic trypsinogen in urin (irAT/u) is elevated in AP, and has recently been proposed as a rapid diagnostic instrument and severity predictor. These results have not been confirmed by other groups, and irAT/u has not been further characterized. The concentration of immun
A known problem of the HCCI engine is its lack of direct control andits requirements of feedback control. Today there exists severaldifferent means to control an HCCI engine, such as dual fuels,variable valve actuation, inlet temperature and compression ratio.Independent of actuation method a sensor is needed. In this paper weperform closed-loop control based on two different sensors, pressureand
A systematic review of radiation therapy trials in several tumour types was performed by The Swedish Council of Technology Assessment in Health Care (SBU). The procedures for evaluation of the scientific literature are described separately (Acta Oncol 2003; 42: 357-365). This synthesis of the literature on radiation therapy for non-small cell lung cancer (NSCLC) is based on data from 4 meta-analys
We present evidence for ultra-fast dissociation of molecular ammonia when photo-excited to the Nls --> 4a(1) core-hole state. This finding is based on resonant Auger spectroscopical results as well as qualitative arguments concerning the photon energy dependence of the Auger structures. Calculations of the excited state potential based on the Z + l approximation were performed. Both the calculatio
Background. Plasma markers for intestinal ischemia have not proven to be accurate. The value of L-lactate is unclear. Experimental models based on open surgery confound the effects of surgical trauma with that of ischemia. The aim was to create an endovascular model for acute superior mesenteric artery thromboembolism, and then to study L-lactate and lactate dehydrogenase (LD) activity in plasma a
Question: How can we link genotypic, phenotypic, individual, population, and community levels of organization so as to illuminate general ecological and evolutionary processes and provide a framework for a quantitative, integrative evolutionary biology? Framework: We introduce an evolutionary framework that maps different levels of biological diversity onto one another. We provide (1) an overview
The first evidence for excited states in In-101 is presented. In-101 is the lightest In isotope observed in an in-beam experiment. Two gamma-ray transitions at 1309 and 341 keV, respectively, are strong candidates for a cascade to the ground state in this nucleus. In shell-model terms it has one proton hole and two neutron particles outside the double shell closure at Sn-100. New ideas for improvi
The Trianon treaty has been a prominent site of memory in Hungarian historical culture from the day it was undersigned on 4 June 1920. 564,000 Hungarian Jews became victims of the Holocaust. In the first years after the end of World War II, the Holocaust was not a concept in Hungarian politics and historical culture. In the interwar period, in Hungarian historical culture the Trianon syndrome exhi
