GenoMEL, comprising major familial melanoma research groups from North America, Europe, Asia, and Australia has created the largest familial melanoma sample yet available to characterize mutations in the high-risk melanoma susceptibility genes CDKN2A/alternate reading frames (ARF), which encodes p16 and p14ARF, and CDK4 and to evaluate their relationship with pancreatic cancer (PC), neural system

Om tillblivelsen av Karl X Gustav-statyn samt dess betydelse från invigningen 1896 och ett århundrade framåt.

Polynomial composition is the operation of replacing the variables in a polynomial with other polynomials. In this paper we give a sufficient and necessary condition on a set Theta of polynomials to assure that the set F circle Theta of composed polynomials is a SAGBI basis whenever F is.

There is an ongoing trend towards higher automation level in process control systems. The purpose of a plant is to manufacture some product at a high production rate with a consistent quality, while minimizing the use of resources in terms of energy consumption, raw material and labor. With a higher degree of autonomy in the control system, it is possible to improve all these aspects, thus increas

In this article, we turn first to a brief discussion of feminist contributions in the field of security, defense, and collective identity, and then argue that Swedish nationalism is tied to a particular form of collective identity formation through the practice of conscription. Drawing on Elshtain's notions of 'just warriors' and 'beautiful souls', we go on to spell out how women, historically, ha

The importance, legitimacy and role of second-order probabilities are discussed. Two descriptive models of the use of second-order probabilities in decisions are presented. The results of two empirical studies of the effects of second-order probabilities upon the rank orderings of bets are summarized briefly. The bets were of three basic types and involved a wide variety of first- and second-order

A new batch microcalorimetric vessel for the determination of enthalpies of dissolution of small amounts of easily or slightly soluble solids was developed at University of Lund, Sweden and was tested at University of Porto, Portugal. The vessel forms part of a series of twin heat conduction microcalorimeters. In a series of consecutive dissolution steps up to four samples, each 0.1-3 mg, can be i

It is commonly assumed that soil-N-15-labelling provides reliable estimates of N-2 fixation in trees by matching N-2-fixing and non-N-2-fixing tree pairs. As root system is a key parameter in determining suitability of the tree pairs, we compared root architecture of Acacia cyanophylla Lindl. and Casuarina glauca Sieber ex. Spreng. (two N-2-fixing trees) with Eucalyptus camaldulensis Dehn. and Cer

High cadmium exposure is known to cause bone damage, but the association between low-level cadmium exposure and osteoporosis remains to be clarified. Using a population-based women's health survey in southern Sweden [Women's Health in the Lund Area (WHILA)] with no known historical cadmium contamination, we investigated cadmium-related effects on bone in 820 women (53-64 years of age). We measured

Prevention of first time disease or recurrence of coronary heart disease (CHD) is a major task for the health service. Guidelines regarding CHD prevention have been issued but studies have shown that treatment goals are inadequately met in clinical practice and there is urgent need for improved methods of implementation of guidelines. There is also a need for better risk stratification tools in or

Abstract is not available

This paper gives an account of progress made in a study commenced during 2004, and previously reported. The theme is contextual analysis in requirements shaping practice. The context is organizational development within a relatively new University department. The Strategic Systemic Thinking Framework is used as the basis for inquiry. The paper outlines the process followed in carrying out the stud

Variants of hepatitis C virus (HCV) from a single infected blood donor and 13 viraemic recipients who were traced were examined by sequencing and cloning to determine the extent of virus diversity in hypervariable region 1. Serum-derived viral isolates were studied from the donor when his HCV infection was discovered in 1993, in his recipients that year (0·3–5 years post-transfusion) and 5 years l

Cold protective clothing was studied in 2 European Union projects. The objectives were (a) to examine different insulation calculation methods as measured on a manikin (serial or parallel), for the prediction of cold stress (IREQ); (b) to consider the effects of cold protective clothing on metabolic rate; (c) to evaluate the movement and wind correction of clothing insulation values. Tests were ca

The redox potentials of the multicopper redox enzyme bilirubin oxidase (BOD) from two organisms were determined by mediated and direct spectroelectrochemistry. The potential of the T1 site of BOD from the fungus Myrothecium verrucaria was close to 670 mV, whereas that from Trachyderma tsunodae was > 650 mV vs. NHE. For the first time, direct electron transfer was observed between gold electrodes a

Abstract is not available