The problem whether endogenous nitric oxide (NO) may serve as a true physiological regulator of vascular tone in vivo was approached by testing its role during graded acute haemorrhage with the aid of the nitric oxide synthase (NOS) inhibitor L-NAME. The study was performed on the vascular bed of cat skeletal muscle with a technique permitting quantitative recordings of vascular resistance in the

Objective: To determine if the correlation between magnitude of creatine kinase-myocardial band release after coronary artery bypass surgery and 6-month mortality is comparable to that of patients admitted with an acute coronary syndrome. Methods: The GUARDIAN trial tested the efficacy of cariporide, an Na+/H+ exchange inhibitor, on reduction of myocardial ischemia or death in high-risk patients.

Traditional fragmented and mechanistic science is unable to cope with issues about sustainability, as these are often related to complex, self-organizing systems. In the paper, sustainable development is seen as an unending process defined neither by fixed goals nor by specific means of achieving them. It is argued that, in order to understand the sources of and the solutions to modern problems, l

Genetic factors appear to contribute to the severity and progression of diabetic retinopathy. We assessed the associations of the C807T and Glu505Lys variants of the glycoprotein Ia (alpha(2) integrin) subunit of the platelet/endothelial collagen receptor and risk of retinopathy in a population-based survey of 288 diabetic patients in one Swedish community. Neither variant was associated with reti

Naturally grown fruit-bodies of Suillus luteus, S. bovinus and S. variegatus were subjected to Py-GC. The pyrograms obtained were statistically analysed and classified with a multivariate classification program (SIMCA). The class describing the S. bovinus pyrograms was significantly separated from both the S. luteus and the S. variegatus classes, while these two classes showed some over-lapping wh

The effect of a second mutant allele (V1991, here denoted rn*) at the PRKAG3 (RN) locus on carcass composition was determined in 334 pigs, entire males and females, from crosses between Swedish Hampshire (H) and Finnish Landrace (L) (H x LH; LH x H; LH x LH). Pigs were classified according to DNA test into the following PRKAG3 genotypes: RN-IRN- (23%), RN-/rn(-) (24%), RN-/rn* (33%), rn(+)/rn(+) (

When Harry Sawyerr wrote his essay "What is African Theology?", published first in African Theological Journal, vol. 4 (1971), it appeared from its contents that he was making short comments about James Cone's Black theology that could have disappeared in the midst of more pressing African theological issues. Sawyerr's article was not primarily intended as a critique of Cone's Black theology; inst

The present work describes a flow injection analysis system incorporating amperometric biosensors for acetate monitoring. Tri-enzyme-modified electrodes were fabricated by immobilizing acetate kinase (AK), pyruvate kinase (PK) and lactate dehydrogenase (LDH) into a poly(ethyleneglycole) diglycidyl ether (PEGDGE) film also containing Brilliant Cresyl Blue (BCB) as an electrochemical mediator. The c

This thesis is based on experimental work carried out during the period 1968-1972. The whole investigation is sponsored by the Swedish Council for Building Research and has been performed at the department of Building Materials at the Lund Institute of Technology. The thesis treats the problem frost resistance of building materials, a problem which is far from beeing solved despite much scientifi

This thesis is concerned with laser based techniques for the measurement of fluid dynamical properties and their application to combusting flowfields or flowfields related to combustion. As an introduction, the theory of turbulent flows and combustion is shortly presented. An overview of laser based measuring techniques is given. Next, seven papers are included. The main topic of papers 1 and 2 is

The basic ideas of k(t)-factorization and CCFM parton evolution is discussed. The unintegrated gluon densities, obtained from CCFM fits to the proton structure function data at HERA are used to predict hadronic final state cross-sections like jet production at HERA, but also comparisons with recent measurements of heavy quark production at the Tevatron are presented. Finally, the k(t)-factorizatio

New strategies for prevention and treatment of type 2 diabetes (T2D) require improved insight into disease etiology. We analyzed 386,731 common single-nucleotide polymorphisms (SNPs) in 1464 patients with T2D and 1467 matched controls, each characterized for measures of glucose metabolism, lipids, obesity, and blood pressure. With collaborators (FUSION and WTCCC/UKT2D), we identified and confirmed

The paper deals mainly with two problems in the epistemology of Frank Plumpton Ramsey. One concerns his account of knowledge, the other his fallibilism. I argue that Ramsey failed to make room for the social aspect of knowledge and, furthermore, that he did not separate the fallibility of our view from its corrigibility. My positive proposal is to combine social reliabilism and corrigibilism with

Popular Abstract in Swedish Avhandlingen behandlar nätverksmekanisk modellering av mekaniska egenskaper hos cellulosafiberfluff. Cellulosafiberfluff består av fibrer utvunna från trä, och används bl a i blöjor och isoleringsmaterial. En nätverksmekanisk modell är en typ av mikro-mekanisk modell. Principen för denna typ av modell är att man gör antaganden för hur materialet fungerar på mikro-nivåA network mechanics model for cellulose fibre fluff is proposed. 2D and 3D versions of the model have been implemented and the influence of various micro-level parameters on the global mechanical performance has been determined by means of computer simulations. Model networks composed of bonded fibres of arbitrary distribution in length, curvature, cross-section, stiffness and strength were inves