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Estimating operational releases of 14C and 3H of the GE-Hitachi BWRX-300 & Rolls-Royce SMR using full-core modeling in Serpent 2

The purpose of this project was to find estimates of the operational releases of 14C and 3H from new SMR technology that is being considered in Sweden, namely the Rolls-Royce SMR and the GE-Hitachi BWRX-300. To achieve this goal, models of the reactors of interest were made in the continuous-energy Monte-Carlo neutron and photon transport code Serpent, where the production of 14C and 3H could then

Speedy A governs non-homologous XY chromosome desynapsis as a unique prerequisite for XY loop-axis organization

In mouse early pachytene spermatocytes, the X and Y chromosomes undergo rapid non-homologous (NH) synapsis and desynapsis, but the functional significance remains unknown. Here, we report that pachynema-specific knockout of Speedy A (SpdyA) from telomeres caused persistent Y-X NH synapsis, with the entire Y axis synapsed onto the X axis. This persistent Y-X NH synapsis did not interrupt meiotic se

Preserving Marvels of Fandom: Constructing the Context of Marvel Cinematic Universe Fandom on Reddit and Tumblr

Fan engagement on social media platforms presents significant challenges for digital preservation due to their dynamic and evolving character, spurred by the platforms’ data-generative and algorithmic features, as well as commercial logic. These characteristics pose problems when capturing information about the context of fan engagement. Context sheds light on the environment, setting or circumstaFan engagement on social media platforms presents significant challenges for digital preservation due to their dynamic and evolving character, spurred by the platforms’ data-generative and algorithmic features, as well as commercial logic. These characteristics pose problems when capturing information about the context of fan engagement. Context sheds light on the environment, setting or circumsta

Compassion Fatigue in Swedish Teachers : Reduced Compassion and the Role of Teacher–Student Interaction Quality and Professional Self-care

Compassion fatigue (CF), a diminished empathic capacity resulting from prolonged exposure to others’ distress, is an emerging concern in the teaching profession. This study investigates the prevalence and predictors of CF among Swedish teachers, with a particular focus on reduced compassion toward students. Drawing on the job demands-resources model and the compassion fatigue resilience model, we

Rule of Law with Chinese Characteristics : A Contested Landscape

The concept of the rule of law has been a central issue in China for the past two decades, gaining even greater prominence under Xi Jinping’s leadership. This article examines the development of the rule of law in China, drawing on insights from local Chinese scholarship as a vital source for understanding the situation. By analyzing the most cited research articles in the China National Knowledge

Embodied Entanglements : Gender, Identity, and the Corporeal in Asia

Ideas on the (human) body, gender, and identity lie at the core of many socio-political issues and cultural trends in Asia today, while also inspiring innovative research on artistic expression from Asia's past. By focusing on socio-political as well as cultural issues from diverse geographical and historical contexts, this book highlights complex links and interactions that bind these three inter

Bragg Diffraction Imaging : Overcoming Angular Uncertainty

Probing the internal structure of crystalline materials is vital for understanding and optimizing their functional properties, especially in semiconductors and multiferroics, where nanoscale distortions such as strain and lattice tilt can dramatically affect performance. Among various characterization tools, X-ray diffraction imaging offers a unique combination of deep penetration, nondestructive

Pancreatic Adenocarcinoma : Long-Term Outcomes of Adjuvant Therapy in the ESPAC4 Phase III Trial

PURPOSE The ESPAC4 trial showed that adjuvant chemotherapy with gemcitabine plus capecitabine (GemCap) produced longer overall survival (OS) than gemcitabine monotherapy. Subsequently, the PRODIGE24-CCTG PA.6 trial showed even longer survival for modified fluorouracil, folinic acid, irinotecan, and oxaliplatin (mFOLFIRINOX) than gemcitabine but had more restrictive eligibility criteria. Our aim wa

Vertical structure of an exoplanet’s atmospheric jet stream

Ultra-hot Jupiters, an extreme class of planets not found in our Solar System, provide a unique window into atmospheric processes. The extreme temperature contrasts between their day and night sides pose a fundamental climate puzzle: how is energy distributed? To address this, we must observe the three-dimensional structure of these atmospheres, particularly their vertical circulation patterns tha

Surface Formation Pathway of Nitrogen- and Sulfur-Containing Organic Compounds on Ammonium Sulfate

The formation of nitrogen- and sulfur-containing organic compounds (N-Org and S-Org) is important for atmospheric secondary organic aerosol (SOA) production, thereby influencing air quality and global climate. However, the mechanisms underlying N-Org and S-Org formation on aerosol particle surfaces are poorly understood due to the limited availability of surface-sensitive analytical techniques. Th

Characterization of emissions from a turbojet engine running on sustainable aviation fuels, blends and conventional jet A1

Aviation contributes to air pollution and significantly impacts climate change. Sustainable aviation fuels (SAFs) offer a potential solution to reduce CO2 emissions with the possible co-benefit of reducing emissions of particles. This study evaluates emissions of a turbojet engine using conventional Jet A1 fuel, Biojet fuel (alcohol-to-jet synthetic kerosene with aromatics, ATJ-SKA), hydrotreated

Endothelial Cell pY397-FAK Expression Predicts the Risk of Breast Cancer Recurrences after Radiotherapy in the SweBCG91-RT Cohort

Purpose: Identifying biomarkers of radiotherapy (RT) response is important for optimizing the treatment of early breast cancer. In this study, we tested the interaction between endothelial cell (EC) expression of phospho-Tyr397-FAK (pY397-FAK) and adjuvant-RT on clinical outcomes after breast-conserving surgery (BCS) within a randomized study. Preclinical data suggest an enhanced effect of RT on l

Sex differences in patient-reported outcome measures and the association with clinical factors in axial spondyloarthritis patients treated with tumour necrosis factor inhibitors

Objectives: To investigate sex differences in patient-reported outcome measures (PROMs) among axSpA patients initiating their first TNFi and identify factors contributing to these disparities over the follow-up. Methods: Data were included from 15 EuroSpA registries and consisted of axSpA patients initiating their first TNFi, with ≥2 measurements for each analysed PROM (BASDAI and BASFI, scale 0–1

Temporal dynamics and environmental controls of carbon dioxide and methane fluxes measured by the eddy covariance method over a boreal river

Boreal rivers and streams are significant sources of carbon dioxide (CO2) and methane (CH4) for the atmosphere. Yet the controls and the magnitude of these emissions remain highly uncertain, as current estimates are mostly based on indirect and discrete flux measurements. In this study, we present and analyse the longest CO2 and the first ever CH4 flux dataset measured by the eddy covariance (EC)

A Pathway Toward Sub-10 nm Surface Nanostructures Utilizing Block Copolymer Crystallization Control

It is elucidated how crystallization can be used to create lateral surface nanostructures in a size regime toward sub-10 nm using molecular self-assembly of short chain crystallizable block copolymers (BCP) and assist in overcoming the high-χ barrier for microphase separation. In this work, an amphiphilic double-crystalline polyethylene-b-polyethylene oxide (PE-b-PEO) block co-oligomer is used. A

Spread of the FAR-MRSA clone, a fusidic acid- and meticillin-resistant Staphylococcus aureus ST121, Europe, 2014 to 2024.

We describe the genetic characteristics of a fusidic acid- and meticillin-resistant Staphylococcus aureus (MRSA) clone widespread in Europe, based on whole genome sequences from 317 isolates. The clone is causing impetigo and other skin and soft tissue infections, primarily in young children. Comparison with publicly available S. aureus ST121 sequences showed that the clone is clearly distinct fro