Aim: To investigate whether there is any pharmacokinetic rationale for the common practice of administering vincristine to adolescents at relatively lower doses than those to younger children. Methods: A total of 98 children, aged 1.3-17.3 y, with acute lymphoblastic leukaemia (ALL) were studied on day I of induction therapy. Plasma samples were drawn before and 10, 30, 360 and 1380 min after inje

We have observed strong correlations between simultaneous and co-located measurements of aerosol optical depth and column amounts of carbon monoxide, hydrogen cyanide, formaldehyde and ammonia in bushfire smoke plumes over SE Australia during the Austral summers of 2001/2002 and 2002/2003. We show how satellite-derived aerosol optical depth maps may be used in conjunction with these correlations t

Analys av FW Murnaus Nosferatu (1922) och den fiktionaliserade berättelsen om inspelningen av filmen i Elias Merhiges Shadow of the Vampire (2000).

Anaerobic degradation of a semi-solid waste with a total solids content of 4% particulate matter, much of it insoluble, was investigated in four laboratory-scale reactors. Two of the reactors were equipped with different textile materials for immobilisation of microorganisms, while the other two were used as continuously-stirred-tank reactor references, A constant organic loading rate and hydrauli

Two new for science lichen species from the family Teloschistaceae (namely Caloplaca karadagensis Khodosovtsev & S. Kondr. and Caloplaca geleverjae Khodosovtsev & S. Kondr.) are described.

Lactobacillus isolates from healthy Estonian and Swedish children were characterised by a lectin typing technique; 56 isolates from six species (L. acidophilus, L. paracasei, L. plantarum, L. fermentum, L. brevis and L. buchneri) were tested. The typing system was based on an agglutination assay with a panel of six commercially available lectins, which,were chosen on the basis of their carbohydrat

Study objectives: In 1996, researchers in Sweden initiated a collaborative randomized study comparing lung volume reduction surgery (LVRS) and physical training with physical training alone. The primary end point was health status; secondary end points included survival and physiologic measurements. Design: After an initial 6-week physical training program, researchers' patients were randomized to

A box-tree is a bounding-volume hierarchy that uses axis-aligned boxes as bounding volumes. The query complexity of a box-tree with respect to a given type of query is the maximum number of nodes visited when answering such a query. We describe several new algorithms for constructing box-trees with small worst-case query complexity with respect to queries with axis-parallel boxes and with points.

BACKGROUND: To study the relationship between different types of acidemia in umbilical artery blood at birth, fetal heart rate (FHR) patterns during labor, and infant long-term outcome. METHODS: Case-control study of 48 infants with pure high base deficit (base deficit (BD) > or = 12 mmol/L and pCO2 < 8.0 kPa), 51 with mixed acidemia (BD > or = 12 mmol/L and pCO2 > or = 8.0 kPa), born at or after

The effect of core polarization on binding energies, term splitting, fine structure, and transition probabilities is investigated for the low lying states 4s2S, 3d2D, 4p2P(o) in Ca II and 4s2(1)S, 4s4p1,3P(o) in Ca I. Results from inclusions of core polarization in the form of model potentials are compared with explicit MCHF calculations, and the accuracy of the different approaches is discussed.

Abstract in French La géométrie du tissue urbain a une grande influence sur le microclimat et influence donc le confort thermique extérieur des habitants et, le microclimat urbain influence à son tour indirectement le climat intérieur. Une mauvaise adaption climatique des environnements urbains a souvent pour conséquence l'utilisation d'une climatisation active et ainsi une augmentation de la cons

A jawed polychaete fauna from the upper 30 in of the Upper Ordovician Sylvan Shale (Richmondian, Ash-ill) of Oklahoma is described, based on recovered scolecodonts (polychaete jaws). The fauna includes members of six families: Paulinitidae, Ramphoprionidae, Polychaetaspidae, Atraktoprionidae, Hadoprionidae, and Kalloprionidae. Ten species are identified and one new paulinitid species, Ketmerites (

Objectives. Accidents in health care, resulting in injury or death to the patient, are a matter of considerable concern. The aim of this study is to examine whether system weaknesses can contribute to these accidents, and if so, how. Design. Eight consecutive accidents reported to the Health Authority in Sweden were analysed using MTO (Man-Technique-Organization) analysis. Setting. Emergency care

Background Phobic postural vertigo is characterized by dizziness in standing and walking despite normal clinical balance tests. Patients sometimes exhibit anxiety reactions and avoidance behavior to specific stimuli. Different treatments are possible for PPV, including vestibular rehabilitation exercises, pharmacological treatment, and cognitive behavioral therapy. We recently reported significant