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Daphnids adaptive strategies to UV radiation

This thesis focuses on the adaptive strategies of daphnids that allows them to maintain stable populations while deal with UV radiation, highlighting the differences in the responses that populations with different evolutionary histories may have.Although exposition to lethal doses in nature is unlikely, sub-lethal UV-B radiation doses may have strong impacts on zooplankton. This work initiates wi

ChPT loops for the lattice : Pion mass and decay constant, HVP at finite volume and nn̄ -oscillations

I present higher loop order results for several calculations in Chiral perturbation Theory. 1) Two-loop results at finite volume for hadronic vacuum polarization. 2) A three-loop calculation of the pion mass and decay constant in two-flavour ChPT. For the pion mass all needed auxiliary parameters can be determined from lattice calculations of ππ-scattering. 3) Chiral corrections to neutron-anti-ne

Mutation, methylation, and gene expression profiles in dup(1q)-positive pediatric B-cell precursor acute lymphoblastic leukemia

High-throughput sequencing was applied to investigate the mutation/methylation patterns on 1q and gene expression profiles in pediatric B-cell precursor acute lymphoblastic leukemia (BCP ALL) with/without (w/wo) dup(1q). Sequencing of the breakpoint regions and all exons on 1q in seven dup(1q)-positive cases revealed non-synonymous somatic single nucleotide variants (SNVs) in BLZF1, FMN2, KCNT2, L

The Unbound Brain

Special issue of "Culture Unbound". Through six original articles, the issue investigates a variety of cultural and scientific discourses and practices that in different ways are related to neuroscience and the brain.

BrownoutCC: Cascaded Control for Bounding the Response Times of Cloud Applications

Cloud computing has emerged as an inexpensive and powerful computing paradigm, to the point that now even applications with hard deadlines are executed in the cloud. It may happen, due to unexpected events, that an application becomes popular and receives a lot of attention and client requests in a short period of time. Provisioning computing capacity for such applications is quite a difficult tas

Glucocorticoid use and factors associated with variability in this use in the Systemic Lupus International Collaborating Clinics Inception Cohort

Objectives. To describe glucocorticoid (GC) use in the SLICC inception cohort and to explore factors associated with GC use. In particular we aimed to assess temporal trends in GC use and to what extent physician-related factors may influence use. Methods. Patients were recruited within 15 months of diagnosis of SLE from 33 centres between 1999 and 2011 and continue to be reviewed annually. Descri

Ensuring continuity in teaching at a university based on impermanent employment

This paper is based on a roundtable discussion held in September 2016 as part of the Pedagogical Inspiration Conference for teachers at the Faculties of Humanities and Theology at Lund University (LU). The roundtable was meant to focus specifically on the consequences of the lack of permanent teaching positions for the quality of the pedagogical work carried out at LU. However, as will be discusse

A Bit-Encoding Based New Data Structure for Time and Memory Efficient Handling of Spike Times in an Electrophysiological Setup

Recent neuroscientific and technical developments of brain machine interfaces have put increasing demands on neuroinformatic databases and data handling software, especially when managing data in real time from large numbers of neurons. Extrapolating these developments we here set out to construct a scalable software architecture that would enable near-future massive parallel recording, organizati

Clinicians’ use of breast cancer risk assessment tools according to their perceived importance of breast cancer risk factors : an international survey

The BOADICEA breast cancer (BC) risk assessment model and its associated Web Application v3 (BWA) tool are being extended to incorporate additional genetic and non-genetic BC risk factors. From an online survey through the BOADICEA website and UK, Dutch, French and Swedish national genetic societies, we explored the relationships between the usage frequencies of the BWA and six other common BC ris

Alcohol Consumption in Obese Patients Before and After Gastric Bypass as Assessed with the Alcohol Marker Phosphatidylethanol (PEth)

Introduction: Roux-en-Y gastric bypass (RYGB) causes more rapid and enhanced absorption of alcohol. RYGB patients have also been reported to use more inpatient care for alcohol-related disease than do patients after other bariatric procedures. The present study was designed to evaluate alcohol consumption level before and after gastric bypass using a sensitive and specific alcohol biomarker. Mater

Different angioregulatory activity of monovalent galectin-9 isoforms

Galectin-9 consists of two peptide-linked carbohydrate recognition domains (CRDs), but alternative splicing and proteolytic processing can give rise to multiple galectin-9 isoforms. Some of these consist of a single CRD and can exert different functions in cell biology. Here, we explored the role of these galectin-9 isoforms in endothelial cell function and angiogenesis. For this, we compared the

The PanCareSurFup cohort of 83,333 five-year survivors of childhood cancer : a cohort from 12 European countries

Childhood cancer survivors face risks from a variety of late effects, including cardiac events, second cancers, and late mortality. The aim of the pan-European PanCare Childhood and Adolescent Cancer Survivor Care and Follow-Up Studies (PanCareSurFup) Consortium was to collect data on incidence and risk factors for these late effects among childhood cancer survivors in Europe. This paper describes

Vulnerable Normality: Popular Neuroimaging and the Discursive Logic of the (Dis)able(d) Brain

The aim of this article is to analyse popular neuroimaging of (dis)able(d) brains as a cultural phenomenon, as well as to explore how there has been, during the last decades, a subtle but important change in the way “normal” brains are depicted in popular science. Popular neuroimaging is introduced and used as an empirical basis to analyse what Fiona Kumari Campbell sees as a critique against able

Rheological and thermal transport characteristics of a transformer oil based ferrofluid

Ferrofluids based on insulating liquids are intensively studied as a potential substitute of liquid dielectric in high voltage technologies. In this work we focus on the experimental investigation of flow and thermal transport characteristics of a ferrofluid based on transformer oil (Mogul) and iron oxide nanoparticles. The magneto-rheological behavior of the ferrofluid was studied by a rotational

Probing Water Mobility in Human Dentine with Neutron Spectroscopy

The aim of this study was to investigate hydrogen mobility within innate and demineralized human dentine. Dentine sections from extracted human molars, demineralized or not, were analyzed by combining neutron spectroscopy with thermal analysis. For the thermal analysis of the samples, differential scanning calorimetry and thermal gravimetric analysis, coupled with Fourier transform infrared spectr