IMPORTANCE: The value of microRNAs (miRNAs) as biomarkers has been investigated in various clinical contexts. Initial small-scale studies suggested that miRNAs might be useful indicators of outcome after cardiac arrest. OBJECTIVE: To address the prognostic value of circulating miRNAs in a large cohort of comatose patients with out-of-hospital cardiac arrest. DESIGN, SETTING, AND PARTICIPANTS: This

The stability of a multi-controller system is analyzed using Lyapunov theory. Stability is guaranteed by a switching strategy determined by a combination of separate Lyapunov functions for the different controllers. The behavior on sliding surfaces is analyzed using non-smooth analysis according to Filippov. Two examples illustrate the theory.

Targeted temperature management (TTM) of 32-34 °C has been the standard treatment for out-of-hospital cardiac arrest since clinical trials in 2002 showed benefits to survival and neurological outcome. Recently, this treatment has been challenged by another clinical trial showing no difference in outcome between TTM of 33 °C and 36 °C. This protocol describes the methodology for a meta-analysis det

OBJECTIVE: To investigate whether the location and extent of the CT hyperdense artery sign (HAS) at presentation affects response to IV alteplase in the randomized controlled Third International Stroke Trial (IST-3).METHODS: All prerandomization and follow-up (24-48 hours) CT brain scans in IST-3 were assessed for HAS presence, location, and extent by masked raters. We assessed whether HAS grew, p

Previous work in the areas of organizational trust repair and crisis communication has provided conflicting answers to the question of whether denial can be more effective than apology in repairing stakeholder trust in a company following an integrity-based violation. This article reportsthe results of an experiment designed to (i) test the effects of these two strategies on individuals’ trust in

The stable isotope of carbon, 13C, has been used in several studies for source characterization of carbonaceous aerosol since there are specific signatures for different sources. In rural areas, the influence of different sources is complex and the application of δ13C for source characterization of the total carbonaceous aerosol (TC) can therefore be difficult, especially the separation between bi

Denna avhandling har tre utgångspunkter. Den första är den europeiska sociala dialogen (ESD), vilken har kritiserats för att sakna kapacitet för att förbättra arbetsvillkor i EU. Den andra är det globala systemet för kollektivavtal och förhandlingar som har utvecklats genom ITFs kampanj mot bekvämlighetsflagg (ITF FOC), vilket anses ha kapacitet att förbättra villkor för sjömän på global nivå. DenThere are three starting points for this thesis. First, there is the system of ESD, which is criticised for lacking capacity to improve the working conditions within the EU. Secondly, there is the system developed through the global ITF FOC campaign, which is considered to have capacity to improve working conditions for seafarers at a global level. Thirdly, there is the theory on self-referential

INTRODUCTION: A multimodal approach to prognostication of outcome after cardiac arrest (CA) is recommended. Evidence for combinations of methods is low. In this post-hoc analysis we described findings on head computed tomography (CT) after CA. We also examined whether generalised oedema on CT alone or together with the biomarker Neuron-specific enolase (NSE) could predict poor outcome.METHODS: Pat

AIM: To examine the psychometric properties of a modified version of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), for a cardiac arrest population (IQCODE-CA).METHODS: The IQCODE-CA, a 26-item observer-reported questionnaire, was completed by informants, defined as relatives or close friends, of 268 out-of-hospital cardiac arrest (OHCA) survivors who participated in the

INTRODUCTION: It is hypothesized that cerebral hypoperfusion promotes the development of Alzheimer pathology. We therefore studied whether longstanding cerebral hypoperfusion is associated with Alzheimer pathology in nondemented humans.METHODS: Cerebral blood flow and amyloid β ((18)F-Flutemetamol) positron emission tomography retention were assessed in eleven patients with unilateral occlusion of

From at least the Late Neolithic through the end of the Bronze Age and onwards, people continued to inhabit the settlement of Asine. For this reason, the site makes an interesting starting point for discussing long term change. This short paper presents new data on the animal bones from Bronze Age Asine. The data set is used for a zooarchaeological discussion of the site from a diachronic perspectFrom at least the Late Neolithic through the end of the Bronze Age and onwards, people continued to inhabit the settlement of Asine. For this reason, the site makes an interesting starting point for discussing long term change. This short paper presents new data on the animal bones from Bronze Age Asine. The data set is used for a zooarchaeological discussion of the site from a diachronic perspect

Recent studies find that defection from one's most preferred party to some other party is as common under proportional representation (PR) as it is in plurality systems. It is less elaborated how election-specific contextual factors affect strategic vote choice under PR. This study looks at the impact of two potentially important contextual factors: parties’ coalition signals about cooperation wit

The paper investigates possible effects of cross-linguistic variation on measures of syntactic complexity in 60 texts from learners of L2 English, L3 French and L4 Italian at CEFR level A and CEFR level B. A previous study by Gyllstad et al. (2014) showed significant differences between proficiency levels for two length measures of complexity in English and French, but not in Italian. In this papeThe paper investigates possible effects of cross‐linguistic variation on measures of syntactic complexity in 60 texts from Swedish L1 learners of English, French and Italian as foreign languages at CEFR level A and CEFR level B. A previous study on the same learners and texts, showed significant differences between proficiency levels for two length measures of complexity in English and French, but

För ungefär 350 miljoner år sedan utvecklade de första insekterna förmågan att flyga och har sedan dess dominerat våra terrestra miljöer. Trots sina pyttesmå hjärnor och avsaknad av avancerade kontrollinstrument så lyckas flygande insekter på många vis utkonkurrera modern flygteknik. Humlor och bin kan till exempel leta upp en födokälla långt ifrån sitt bo, återvända hem igen och sedan upprepa denDespite their small brains and tiny eyes, flying insects are capable of detecting and avoiding collisions with moving obstacles, and with remarkable precision they navigate through environments of different complexity. For this thesis, I have investigated how bumblebees use the pattern of apparent image motion that is generated in their eyes as they move through the world (known as optic flow), in

The development of cities is increasingly threatened by a worldwide water crisis. Urban water services (including drinking water, sanitation and drainage) are facing complex and multiple pressures, which are becoming increasingly frequent and severe. These pressures include floods, and the depletion, pollution and degradation of water resources and their associated ecosystems. These diverse pressu