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Plasma protein homeostasis in chronic hemodialysis patients

The concentrations of 25 plasma proteins were measured in 29 patients with chronic renal insufficiency. All the patients had terminal renal failure and were treated with intermittent hemodialysis, but were otherwise in good general condition at the time of investigation. The plasma levels of 8 proteins with Mr

The soft values of SI: Using surveys to assist in providing quality assurance for an SI program

The main goals of SI are usually to improve learning and student performance as well as increasing retention. The achievement of these goals are evaluated based on linking SI attendance with retention and student results (student performance is here often seen as a proxy for learning). However, the objectives with introducing an SI-program at a higher education institute is often so much more than

Postprandial increase in serum creatinine in renal transplant recipients

Daily variation in serum creatinine and the effect of a protein load was studied in 18 patients with renal transplants and in 10 healthy controls. Serum creatinine was analyzed both with a standard Jaffé method and with a specific HPLC technique. Following a protein meal, a 30% increase in serum creatinine levels was noted in both groups, but the rise in absolute terms was more prominent among the

Determination of urinary N-acetyl-beta-glucosaminidase in patients with hypertension and renal artery stenosis

The purpose of the study was to measure the urinary excretion of N‐acetyl‐beta‐glucosaminidase (U‐NAG) in patients suspected of having renovascular hypertension and to compare the enzyme excretion before and after active intervention with operation or percutaneous transluminal renal angioplasty (PTRA). Eighty‐one patients with severe, therapy‐resistant hypertension were examined with regard to ren

Plasma homocysteine in renal failure

Plasma homocysteine in three different groups of patients with chronic renal failure (one group without dialysis, one with CAPD and one with hemodialysis) was increased compared to controls. Another group of patients with slightly reduced renal dysfunction (normal serum creatinine but reduced glomerular filtration rate) did not, however, show increase of plasma homocysteine. The clearance of homoc

Renal arteriovenous shunting in rejecting allograft, hydronephrosis, or haemorrhagic hypotension in the rat

We studied the occurrence of arteriovenous (A-V) shunting in three experimental rat models, namely in rejecting allograft kidney, in uni- or bilateral ureteral obstruction, and in haemorrhagic hypotension. Isografted or sham-operated rats served as controls. Radiolabelled microspheres were injected into the renal artery and the increase in the amount of radioactivity in the lungs was considered to

The use of iohexol clearance to determine GFR in patients with severe chronic renal failure - a comparison between different clearance techniques

The nonionic low-osmolar contrast medium iohexol was used as marker of glomerular filtration rate (GFR) in 53 patients with stable renal function (group I: n = 32, group II: n = 21). All the patients had clearance values < or = 30 ml.min-1.1.73 m-2 body surface; 40 patients < 20 ml.min-1.1.73 m-2 body surface. Simultaneous determinations of renal clearance and plasma clearance, both as slope clear

Inequalities in access to bike-and-ride opportunities: Findings for the city of Malmö

Intermodality or combining more than one transport mode during a single trip has been put forward to facilitate a modal shift from private car to more environmentally friendly modes such as public transport, cycling or walking. Bike-and-ride – that is, integrating cycling and public transport in one trip – is an attractive combination, as cycling as an active and clean mode is faster than walking

Assessing residual renal function and efficiency of hemodialysis - an application for urographic contrast media

Background: In patients on hemodialysis with end-stage renal disease there is an increasing interest in measuring both residual renal function (RRF) and quantity and quality of dialysis because insufficient dialysis gives higher mortality. For that purpose we have measured clearances of two urographic iodine (I) contrast media (CM) with different molecular masses (iohexol 821 u and iodixanol 1,550

Plasma exchange or immunoadsorption in patients with rapidly progressive crescentic glomerulonephritis. A Swedish multi-center study

A therapeutic removal of antibodies may be achieved by immunoadsorption (IA) or by plasma exchange (PE). The aim of this prospective randomised study was to compare the efficacy of these different techniques with regard to treatment of patients with rapidly progressive glomerulonephritis (RPG) having at least 50% crescents. Forty-four patients with a RPG were included for treatment either by IA or

Low risk of contrast-medium-induced nephropathy with modern angiographic technique

Objective and design. A retrospective study of the incidence of contrast‐medium‐induced nephropathy (CMN) in patients with renal insufficiency.Subjects. All angiographies with and without endovascular therapeutic procedures (n=2400) performed at the hospital during 1 year were evaluated. A total of 139 patients were found to have a preangiographic serum‐creatinine (s‐Cr) of 150 μmol L–1 or above.

Raised platelet levels in diabetes mellitus complicated with nephropathy

Objectives To study if elevated platelet levels are found in early and late diabetic nephropathy.Design A retrospective study was performed of platelet count in different subgroups of patients with insulin‐dependent diabetes mellitus, including patients with long and short duration of diabetes and with early signs of nephropathy. Patients with severe renal failure subjected to renal transplantatio

Pharmacokinetics of glibenclamide and its metabolites in diabetic patients with impaired renal function

BACKGROUND: Glibenclamide (Gb) may provoke long-lasting hypoglycaemic reactions, and one of the known risk factors is impaired renal function. We have demonstrated Gb to have a terminal elimination half-life of 15 h, and the main metabolites have a hypoglycaemic effect. With few exceptions, detailed studies on second generation sulphonylureas in diabetics with impaired renal function are lacking.