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Introduction. The aim of the present study was to investigate the impact of age at diagnosis on prognosis in patients treated with curatively intended radiotherapy for NSCLC. Material and methods. This is a joint effort among all the Swedish Oncology Departments that includes all identified patients with a diagnosed non-small cell lung cancer that have been subjected to curatively intended irradia
Recent studies of isolated human islets have shown that glucose induces hormone release with repetitive pulses of insulin and somatostatin in antisynchrony with those of glucagon. Since the mouse is the most important animal model we studied the temporal relation between hormones released from mouse islets. Batches of 5-10 islets were perifused and the hormones measured with radioimmunoassay in 30
Background: The use of tumour necrosis factor (TNF) blocking agents in psoriatic arthritis (PsA) is increasing, and the SSATG register has followed patients with PsA for more than 5 years. The aim of the present work therefore was to present efficacy and tolerability data of TNF-blocking agents on PsA in clinical practice, and to study potential predictors for drug survival (the length of time a p
Queer studies of education and research with lesbian, gay, bisexual, transgender and queer (LGBTQ) kids, tightly connected to anti-homophobia, anti-transphobia and norm-critical activism, have become a growing field with a range of theoretical and political positions and methodological approaches. One of the key contentions within this field is what researchers and activists mean by “queer” in the
How the Internet spawns community and gets its features into offline life is a recurring problem met in searches for “impacts” of its successive iterations in the Middle East and arises particularly in assessing equivocal findings most recently about social media in the Arab Spring uprisings. But the problem is more methodological than ontological: it lies in viewing the Internet through a media l
Small arteries are known to develop functional and structural alterations in hypertension. However, the mechanisms of this remodeling are not fully understood. We hypothesized that altered gene expression is associated with the development of hypertension in mesenteric arteries of spontaneously hypertensive rats (SHR). Three sublines of SHR and normotensive Wistar Kyoto rats (WKY) were studied at
Breast cancer (BC) is one of the leading causes of death among women worldwide. Immunostimulatory treatment has increasingly been used as adjuvant therapy in the last few years, in patients with melanoma and other cancer forms, often with an induction of autoimmunity as a consequence of a successful treatment. We aimed at investigating if coexisting autoimmune diseases (AD) or hypersensitivities (
Correlation coefficient of received signals across a pair of antennas is a key performance indicator for multiple-input multiple-output (MIMO) systems. For multipath environments with uniform 3D angular power spectrum, the signal correlation between two antennas can be exactly calculated from their 3D radiation patterns. When radiation patterns are unavailable, a simplified approach that only requ
In this paper a new third-generation amperometric biosensor for lactose determination is described. The biosensor is based on the highly efficient direct electron transfer (DET) between cellobiose dehydrogenase (CDH) from Phanerochaete sordida (PsCDH) and single walled carbon nanotubes (SWCNT). The SWNCTs were surface modified with aryl diazonium salts of p-phenylenediamine (NH2-PD) and deposited
We present a novel technique to infer ground slope angle from waveform LiDAR, known as the independent slope method (ISM). The technique is applied to large footprint waveforms (similar to 60 m mean diameter) from the Ice, Cloud and Land Elevation Satellite (ICESat) Geoscience Laser Altimeter System (GLAS) to produce a slope dataset of near-global coverage at 0.5 degrees x 0.5 degrees resolution.
The title compound, {[Na(H2O)(4)](6)[V10O28]center dot 2H(2)O}n, crystallized from a H2O/THF/CH3CN solution (pH ca 6)containing equimolar amounts of NaVO3 and N-(2-hydroxybenzyl)-N-(2-picolyl) glycine. In the crystal structure, the decavanadate [V10O28](6-) anion ((1) over bar symmetry)is coordinated, via four terminal oxide ligands of V centres, to two dinuclear [{Na(H2O)(3)}(2)(mu-H2O)(2)](2+) u
To report changes in the tapetal-like reflex in a female carrier of RPGR ORF15 c.3395delA X-linked retinitis pigmentosa (XLRP) between examinations at 16 and 22 years of age, and to report the observation that the tapetal-like reflex faded due to exposure to daylight and reappeared with prolonged dark adaptation at 22 years of age.
Resarch shows the importance of sound environment in health care for healing processses to be effective. Intensive care environments are often caracterized by heavy work load for staff in combination with underdimensioned localities, personel and economy. Results are stress and tension that also affects the well being and recovery for patients. To find yourself in an intensive care unit has more t
Hyperresponsiveness and inflammation are major pathophysiological features of both allergic rhinitis and asthma. The mechanisms behind these are not fully understood. The aims of this thesis were to investigate if cytokines involved in the allergic response can induce airway hyperreactivity by affecting the airway smooth muscle directly and to identify novel mediators involved in allergic airway i
Background and Aim: A recent study in Indian subjects suggested common variants in apolipoprotein C3 (APOC3) (T-455C at rs2854116 and C-482T at rs2854117) to contribute to non-alcoholic fatty liver disease (NAFLD), plasma apoC3 and triglyceride concentrations. Our aim was to determine the contribution of genetic variation in APOC3 on liver fat content and plasma triglyceride and apoC3 concentratio
ATP and ADP inhibit, in varying degrees, several dehydrogenases of the central carbon metabolism of Lactococcus lactis ATCC 19435 in vitro, i.e. glyceraldehyde-3-phosphate dehydrogenase (GAPDH), lactate dehydrogenase (LDH) and alcohol dehydrogenase (ADH). Here we demonstrate mixed inhibition for GAPDH and competitive inhibition for LDH and ADH by adenine nucleotides in single inhibition studies. T
Premise of the study: Storage oil (triacylglycerol) accumulates in tissues such as the embryo and endosperm of seeds and the fruit mesocarp, but seldom in underground organs. As a rare exception, cultivated variants of yellow nutsedge (Cyperus esculentus) contain high amounts of both oil and starch in the mature tubers. Methods: Biochemical analyses and light and electron microscopy were used to s
SUMMARY: Models of service encounters are often fraught by reductionism, describing business relationships as mathematical combinations of dyadic constellations. Metaphors of ideal social relationships (marriages or friendships) are highlighted to stress normative aspects of equal, balanced and long-term business partnerships. However, these approaches are limited in their analytical sensitivity,
