Sökresultat

The importance of immunometabolism in the development of metabolic diseases is clear. Yet, how certain metabolic disorders, such as insulin deficiency (ID), influence immune cell function, and vice versa, is poorly understood. Also, therapeutic strategies to harness the interplay between immune cells and metabolism are lacking. Here, we observe that ID rearranges the immune landscape of the liver,

This article investigates the potential of alternative research terminologyto facilitate the utilisation of existing geographical conceptions of spaceand place in empirical studies of children’s everyday lives. This isachieved by employing Clifford Geertz’s (1974. “‘From the Native’s Pointof View’: On the Nature of Anthropological Understanding.” Bulletin ofthe American Academy of Arts and Science

Purpose:This paper aims to contribute to the understanding of the recirculation of products by empirically exploring, conceptualising and explaining how second-hand goods are made in practices and processes of valuation.Design/methodology/approach: The paper takes a practice theory approach to valuation and draws on an ethnographic study of ReTuna, a second-hand shopping mall, to explore the valua

This article discusses the interweaving of queerness, affect and translation in the asylum process, focusing on the role of legal representatives. Through 16 semi-structured interviews with asylum lawyers in Greece, it explores their collaborative work with queer asylum seekers in preparing a “credible” account. Approaching legal preparation as a process of translating applicants’ emotions into wh

OBJECTIVES: To describe the prevalence of cardiovascular disease (CVD) at the time of diagnosis of adult-onset type 1 (T1D) and type 2 (T2D) diabetes, in a recent cohort and compare to a previous cohort from the same region. Further, to explore factors influencing the prevalence of pre-existing CVD, including age, sex, body mass index (BMI) and C-peptide; in the later cohort also heart failure, hy

Välkommen till framtiden! Men vilken framtid? Framtiden som begrepp är både mångtydigt och politiskt laddat. Å ena sidan framställs den som en naturlig förlängning av det förflutna och som något som kan planeras, styras och förutses. Å andra sidan öppnar begreppet framtider i plural för en kamp mellan olika visioner och en omförhandling av de historieskrivningar som legitimerar vissa framtider fraVälkommen till framtiden! Men vilken framtid? Framtiden som begrepp är både mångtydigt och politiskt laddat. Å ena sidan framställs den som en naturlig förlängning av det förflutna och som något som kan planeras, styras och förutses. Å andra sidan öppnar begreppet framtider i plural för en kamp mellan olika visioner och en omförhandling av de historieskrivningar som legitimerar vissa framtider fra

In the 1970s, researchers and theoreticians of states of consciousnessjointly discussed hypnosis and psychedelic alterations of consciousness,but recent research has mostly kept these topics apart. This paperdiscusses the similarities and differences of hypnosis and psychedelicalterations of consciousness, stressing that states of consciousnessshould not be defined by their preceding contexts. Pre

We live in a post-truth society, where lies, deception, and untruth play an increasingly significant role on the grand political stage. But what about everyday leadership in everyday organisations – what roles do lies play there? This paper develops the notion of mendaciology (Lat. Mendacium: ‘lie,’ ‘untruth’) to address this question empirically. The key idea with a mendaciological approach is to

Kost och konsekvens: Halsbakteriens anpassning till olika miljöer Det är inte helt ovanligt att en normal förkylning övergår i en envis infektion som behöver behandlas med antibiotika. Detta beror på att vissa bakterier som vanligtvis lever fredligt i våra luftvägar plötsligt tar chansen att angripa oss när vårt försvar är som svagast. En sådan bakterieart är icke-typbar Haemophilus influenzae (NNon-typeable Haemophilus influenzae (NTHi) is a commensal with opportunistic tendencies that reside in the human nasopharynx. Since the implementation of the H. influenzae serotype b vaccine, NTHi infection has significantly increased worldwide and is of particular concern to society’s most vulnerable such as young children, elders and immunocompromised individuals. Diseases associated with NTHi a

Structured abstractPurposeThe purpose is to examine how academic researchers perceive the communication dynamics in virtual and hybrid conferences to gain access to communities of knowledge. The paper contributes to the research field of strategic communication.MethodologyUsing a qualitative, interpretive approach, purposive sampling was utilised to recruit a diverse group of researchers from Swed

BACKGROUND: Excessive dietary salt intake is associated with elevated blood pressure and damage to organs including the heart, vasculature, and kidneys. Women are more prone to salt-sensitive hypertension, yet preclinical studies often focus on men.METHODS: To examine sex-specific responses to chronic salt loading, male and female C57Bl6/J mice were fed a high-salt diet (HSD; 8% NaCl) from 7 to 14

Spectral electrical impedance tomography (sEIT) has attracted increasing interest in hydrogeology, biogeosciences, agriculture and environmental studies. However, broad-band sEIT measurements, particularly at frequencies above 50 Hz, have long been challenging due to electromagnetic (EM) coupling effects. Recent advances in instrumentation, data correction and filtering have improved sEIT measurem

Autonomy is central to thinking about democracy and human needs, but the question of how autonomy relates to growth is ambivalent. Is growth necessary to achieve a basic level of autonomy, or is autonomy, in fact, a pre-requisite for post-growth? In this study, we examine this question by focusing on how critical autonomy relates to growth within the domains of democracy, education, and work. Crit

The peak-hour travel demand is the most important operational cost driver for public transport in Sweden. Implementing staggered school starting hours as a measure to spread out the travel demand has proven to be challenging. This study focuses on overcoming barriers to collaboration between public transport authorities, municipalities, and schools concerning school transport planning and school o

Introduction: Neuromelanin containing cell loss, neuroinflammation and synaptic dysfunction are believed to contribute to Parkinson's disease (PD) pathogenesis. [18F]DOPA PET reflects dopamine storage capacity in the putamen, while midbrain off-target retention of [18F]RO948 is hypothesized to reflect neuromelanin. Objectives: To investigate associations between disease duration, cerebrospinal flu

Determining the appropriate duration for traffic conflict observation remains a critical yet unresolved challenge in road safety analysis. Existing approaches lack a quantitative approach to determine adequate sample sizes for general conflict-based applications. This study addresses this gap by proposing an extreme value theory based framework to determine appropriate observation durations, based

This study analyzed daily temperature data from 114 meteorological stations in the Qinling-Daba Mountains from 1980 to 2017, focusing on core zones (CE I ≥ 2274 m, CE II 1321–2274 m) and peripheral zones (PE I 668–1321 m, PE II < 668 m). Using 15 extreme temperature indices computed with RClimDex, we assessed the spatiotemporal patterns, trends, and response to climate warming of extreme temperatu

Cumulate xenoliths from beach boulders in Anaga, Tenerife were analyzed through optical microscopy, scanning electron microscopy (SEM), both EDS and EBSD, and barometric modelling to study the magmatic evolution and volcanic plumbing system of the Anaga massif. Petrographic results indicate crystallization from hydrous basaltic magmas at equilibrium. This was further supported with chemical analy