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Do epigenetic changes cause type 2 diabetes, or do the changes occur only after a person has become ill? A new study by researchers at Lund University provides increased support for the idea that epigenetic changes can cause type 2 diabetes. The researchers behind the new findings published in Nature Communications now aim to develop methods for disease prevention. We inherit our genes from our pa

https://www.ludc.lu.se/article/epigenetic-changes-can-cause-type-2-diabetes - 2025-09-29

An international team of researchers has identified 13 biomarkers that significantly improve the ability to accurately predict cardiovascular disease risk in people with type 2 diabetes. The analysis was led by Lund University, Johns Hopkins University, and the Chinese University of Hong Kong. The study was published in Communications Medicine. Although people with type 2 diabetes are two times mo

https://www.ludc.lu.se/article/new-study-biomarkers-improve-prediction-cardiovascular-disease-type-2-diabetes - 2025-09-29

Much research on diabetes focuses on understanding what happens when the insulin-producing cells are destroyed. Researchers at Lund University have instead chosen to investigate what protects the insulin-producing cells. Their research shows that a protein of the immune system protects the insulin-producing cells from inflammation and death. The study, published in PNAS, is an example of basic res

https://www.ludc.lu.se/article/protein-protects-insulin-producing-cells - 2025-09-29

Diabetes researchers Allan Vaag and Lena Eliasson are the new coordinators of Lund University Diabetes Centre (LUDC) and the strategic research area EXODIAB (Excellence of Diabetes Research in Sweden). Over the next years, they will work to strengthen and further develop ongoing collaborations. Coordinator Allan Vaag and Vice Coordinator Lena Eliasson are new leaders since the beginning of the yea

https://www.ludc.lu.se/article/new-coordinators-strategic-research-area-diabetes - 2025-09-29

Do you think that people with obesity have themselves to blame? Tune H Pers tries to dispel persistent myths through his research on the brain's role in the development of obesity. The diabetes researcher at the University of Copenhagen is now awarded the Leif C. Groop award for his research on obesity and type 2 diabetes. Justification for awarding"Tune H Pers receives the Leif C. Groop Award for

https://www.ludc.lu.se/article/tune-h-pers-receives-award-outstanding-research-obesity-and-diabetes - 2025-09-29

A treatment that has reduced plaque development in mice has now been tested in people with psoriasis. Jan Nilsson at Lund University is one of the researchers behind the clinical study that showed a reduced inflammation of the coronary arteries, which in turn may reduce the risk of dying from a heart attack. People with diabetes may also benefit from the treatment in the future. Cardiovascular res

https://www.ludc.lu.se/article/new-treatment-atherosclerosis-may-reduce-risk-dying-heart-attack - 2025-09-29

Why are some people with obesity protected from type 2 diabetes? Who is at risk of developing gestational diabetes and type 2 diabetes? The Hjelt Diabetes Foundation awards two diabetes researchers at Lund University Diabetes Centre grants for projects that are seeking new answers to these questions. Gestational diabetes happens when the body cannot produce enough insulin during pregnancy. The con

https://www.ludc.lu.se/article/research-obesity-and-gestational-diabetes-receive-support-hjelt-diabetes-foundation - 2025-09-29

People with a hereditary risk of obesity lose as much weight as a result of better diet, exercise and weight loss drugs as the rest of the population, according to an international study presented in The BMJ. “This indicates that even in people at genetic risk of obesity, lifestyle change is an effective way to lose weight”, says Professor Paul Franks of Lund University in Sweden, one of the resea

https://www.ludc.lu.se/article/no-link-between-obesity-gene-and-intentional-weight-loss - 2025-09-29

Interest in type 1 diabetes screening is growing as methods improve and new treatments become available to more patients. New research at Lund University demonstrates how screening for autoimmune diseases can be carried out on a large-scale basis. A new treatment that can delay the onset of type 1 diabetes has been approved for use in the United States. If the treatment Teplizumab becomes availabl

https://www.ludc.lu.se/article/new-method-allows-large-scale-screening-autoimmune-diseases - 2025-09-29

The EAT-Lancet diet is a framework designed to promote environmental sustainability while also preventing common diseases such as type 2 diabetes. How do we know if the diet actually works? An international research team studied seven dietary scores and found that two of them were particularly good at evaluating adherence to the diet. Reliable diet scores are important when developing sustainable

https://www.ludc.lu.se/article/research-paves-way-sustainable-dietary-recommendations - 2025-09-29

The dream of finding the “diabetes gene” is dead. However, partly thanks to Leif Groop – professor and multiple award recipient for his ground-breaking research – we will look at type 2 diabetes in a whole new way in the future. He is now retiring, and in an interview with diabetesportalen.se he looks back on his eventful career in research. The study that since 2006 has been the central hub of th

https://www.ludc.lu.se/article/time-burie-lada-interview-leif-groop - 2025-09-29

Researchers at Lund University in Sweden have discovered that the appetite hormone CART is regulated by glucose and is found in greater quantity in people with type 2 diabetes. “This could be the body’s own defence mechanism to lower blood sugar levels in case of type 2 diabetes”, says Associate Professor Nils Wierup, in charge of the study. The study shows that the appetite hormone CART not only

https://www.ludc.lu.se/article/antidiabetic-effects-discovered-appetite-hormone-cart - 2025-09-29

Heart attack and stroke are common complications of diabetes, as the body's ability to repair and form vessels is impaired. Researchers at Lund University have developed a new substance with the capacity to stimulate vascular repair response and the formation of vessels. In diabetes, the body's ability to repair vascular damage caused by the disease is impaired, which can lead to complications suc

https://www.ludc.lu.se/article/new-peptide-may-reduce-risk-diabetes-complications - 2025-09-29

Precision medicine seeks to reduce errors and improve accuracy in medical and health recommendations, but better evidence is needed to fulfil its potential. An international consortium led by Paul Franks at Lund University presents new guidelines that may increase the clinical relevance of precision medicine research. An international consensus report on precision medicine that was published in Na

https://www.ludc.lu.se/article/new-guidelines-aim-increase-accuracy-precision-medicine-research - 2025-09-29

During his more than 50-year career, diabetes researcher Åke Lernmark has made several significant discoveries that have increased knowledge about type 1 diabetes. His research contributes to creating conditions for a national screening programme in Sweden. In Sweden, around 1,000 children and an equal number of adults develop type 1 diabetes each year. The disease has major consequences for the f

https://www.ludc.lu.se/article/scientist-who-paving-way-screening-type-1-diabetes - 2025-09-29

People with type 2 diabetes have a higher risk of developing cardiovascular disease and dying prematurely due to atherosclerosis. A research team at Lund University in Sweden has now identified molecular mechanisms that may explain the increased risk. Their discovery may lead to more accurate treatments for patients with atherosclerosis and type 2 diabetes in the future. People with type 2 diabete

https://www.ludc.lu.se/article/new-explanation-dangerous-atherosclerotic-plaques-type-2-diabetes - 2025-09-29

Obesity is a common cause of diabetes, heart disease and early death, but risk differs greatly from one person to the next. In work led by researchers at Lund University in Sweden as part of the Innovative Medicine Initiative project SOPHIA, a pioneering clinical risk prediction algorithm has been developed that splits obesity into 5 separate diagnostic profiles each with contrasting health conseq

https://www.ludc.lu.se/article/new-precision-medicine-approach-helps-detect-subgroups-people-obesity-high-risk-diabetes-and-heart - 2025-09-29

Diabetes researcher Joao Duarte specialices in studying what happens in the brain in diabetes. In his research, he is also investigating how diet changes can improve brain function in connection with diabetes. He will be awarded this year's Medeon stipend on the World Diabetes Day Skåne event in Malmö on November 14. "I hope that my research can contribute to an increased awareness of the importan

https://www.ludc.lu.se/article/praised-research-diabetes-and-dementia - 2025-09-29

In 2025, children within the TEDDY study will submit their final samples at research clinics in Sweden, Finland, Germany and the United States. The international study has provided a lot of new knowledge about type 1 diabetes and how the disease develops. Analysis of the samples will continue with the aim of preventing the disease. Sweden and Finland are the two top countries for incidence rates o

https://www.ludc.lu.se/article/new-knowledge-about-type-1-diabetes-large-scale-teddy-study-will-soon-be-completed - 2025-09-29

In type 2 diabetes, the body's ability to release insulin is impaired, which leads to high blood glucose levels. Research led from Lund University shows how the levels of a particular protein are elevated in the pancreas of people with type 2 diabetes. By knocking out the gene for the protein IGFBP7, the researchers discovered that insulin secretion was improved. Reduced insulin secretion leads to

https://www.ludc.lu.se/article/protein-affects-ability-secrete-insulin-type-2-diabetes - 2025-09-29