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Regelbundna undersökningar av kroppens förmåga att ta hand om en given mängd socker hos barn och ungdomar i riskzonen avslöjar att insjuknandet i typ 1 diabetes har ett utdraget förlopp med omväxlande perioder av normal och onormal sockeromsättning. De barn och ungdomar som är undersökta deltar i den amerikanska undersökningen Diabetes Prevention Trail-Type 1 och har alla en antikropp ICA (Islet C

https://www.diabetesportalen.lu.se/artikel/langt-innan-typ-1-diabetes-sviktar-sockret - 2025-12-11

Nyfödda som växer snabbt under de första tre månaderna har som unga vuxna fler riskfaktorer för att senare i livet insjukna i typ 2 diabetes och hjärt- kärlsjukdomar. Det gamla synsättet att det är bra ju snabbare spädbarn växer kommer allt mer på skam. Snabb längdtillväxt liksom snabb viktökning i spädbarnstiden har i flera olika vetenskapligt studier visat sig vara långt ifrån bra.Både födelsevi

https://www.diabetesportalen.lu.se/artikel/framtida-halsorisker-snabbvaxande-bebisar - 2025-12-11

En del var man överens om. Men inte särskilt mycket. Några repliker ur debatten: ”Gentest motiverar till ökad hälsomedvetenhet. De är ett steg mot bättre och individualiserad vård.” ”Vi är inte där än. Ni säljer kunskap ni inte har.” Den offentliga debatten i Malmö med rubriken - ”DNA-tester – den enskildes rättighet eller bara forskarnas ensak?” – kom mycket att handla om tiden var mogen, eller o

https://www.diabetesportalen.lu.se/artikel/delade-meningar-om-kommersiella-gentest - 2025-12-11

Risken att bli fet är två och en halv gång högre för den som har dubbel uppsättning av den mest kända riskgenen för övervikt och fetma. Men bara om fettkonsumtionen är hög. Mindre fett i maten neutraliserar fettgenens skadeverkningar. - Det betyder att det avgörande är vad man äter. I vart fall när det gäller FTO-genen, den klart viktigaste fetmagenen som hittills upptäckts, säger Emily Sonestedt,

https://www.diabetesportalen.lu.se/artikel/matvanor-viktigare-viktigaste-riskgenen-fetma - 2025-12-11

Tre koppar kaffe eller te om dagen nästan halverar risken för typ 2 diabetes. Varför, vad i dryckerna som har denna effekt är det ingen som vet. Flera undersökningar har visat på sambandet minskad diabetesrisk och kaffe- eller tekonsumtion. Nu gör en stor undersökning där drygt 38 000 vuxna har följts också det. Och riskminskningen är inte liten.Tio års uppföljningDeltagarna i den holländska delen

https://www.diabetesportalen.lu.se/artikel/kaffe-och-te-bra-mot-diabetes - 2025-12-11

Amerikanska forskare har funnit ännu ett möjligt nytt användningsområde för metformin. Diabetesmedlet, som trots sin ålder håller ställningarna som ett av världens mest framgångsrika läkemedel, bekämpar också cancer. I kombination med ett cancermedel visar sig metformin vara en utmärkt behandling för att bekämpa en cancertumörs stamceller. Åtminstone när det gäller möss.- Det är ett starkt önskemå

https://www.diabetesportalen.lu.se/artikel/beprovat-diabetesmedel-dodar-cancerceller - 2025-12-11

Stillasittande ökar insulinnivåerna i blodet vilket är ett tecken på sämre insulinkänslighet och i förlängningen diabetes. Motion har motsatt verkan men motionären som slappar desto mer mellan träningspassen är också i farozonen. Genom att minut för minut mäta pulsen under fyra dygn på friska medelålders män och kvinnor fick forskarna fram ett individuellt värde för var och en av deltagarna på hur

https://www.diabetesportalen.lu.se/artikel/motionssparet-kompenserar-inte-sofflocket - 2025-12-11

In a recent study from Lund University, researchers have discovered that metabolic changes in the blood cell, affect the development of blood during the fetal stage. They found a previously unknown metabolic regulator - a kind of switch - which turns out to be crucial for how different types of blood cells develop. In the long run, this could mean that natural killer cells, a type of white blood c

https://www.stemcellcenter.lu.se/article/increased-metabolism-mitochondria-resulted-higher-levels-natural-killer-cells - 2025-12-11

A multidisciplinary research team at Lund University has innovatively tackled what has long been a major problem in stem cell research. The project has now been awarded a Proof of Concept grant from the European Research Council, ERC. Jonas Larsson, Professor of Molecular Medicine, and his research colleague Ludwig Schmiderer, together with Martin Hjort, a researcher at NanoLund, have developed th

https://www.stemcellcenter.lu.se/article/how-nanostraws-can-increase-number-blood-stem-cells - 2025-12-11

Each year, Lund Stem Cell Center presents one of its members with its Article of the Year Award. This year three distinguished nominees contended for the title. Among them, Marie Jönsson, representing the research group Molecular Neurogenetics, was awarded Article of the Year 2021, for their work in revealing how the activation of ancient viruses during brain development causes inflammation. In th

https://www.stemcellcenter.lu.se/article/scc-article-year-award-goes - 2025-12-11

A team of researchers from Lund University and the Lund Stem Cell Center have developed a new memory-efficient tool for single-cell genomic analysis called Scarf. Now available in Nature Communications, this innovative, bioinformatics software has the potential to help researchers navigate a growing treasure trove of data and set them on the path to answering new scientific questions related to hu

https://www.stemcellcenter.lu.se/article/introducing-scarf-memory-efficient-solution-single-cell-genomic-analysis - 2025-12-11

Researchers at Lund University and Lund Stem Cell Center in Sweden have developed a new method for studying age-related brain disorders. The researchers have focused on the neurodegenerative disorder Huntington’s disease and the results have now been published in the journal Brain. Basic medical research often faces the challenge of developing disease models that correspond to specific disease mec

https://www.stemcellcenter.lu.se/article/researchers-reprogram-human-skin-cells-aged-neurons-study-neurodegenerative-disorders - 2025-12-11

Sofia Wijk will defend her Ph.D. thesis on the 8th of September 2022, with a vision to contribute to the development of future cell-based therapies for patients with chronic lung disease. She has dedicated the last several years to better understanding the regenerative properties and processes of stem cells in our airways. In this interview, she tells us about her research, her journey in academia

https://www.stemcellcenter.lu.se/article/phd-defence-interview-sofia-wijk - 2025-12-11

A large amount of lungs donated cannot be used for transplantation. Researchers at Lund Stem Cell Center, Lund University in Sweden and Skåne University Hospital have conducted an animal study bringing hope that more donor lungs could be used in the future. The researchers have launched a pilot study to investigate whether the treatment will have the same positive effects on human beings. About 19

https://www.stemcellcenter.lu.se/article/new-treatment-could-result-more-donor-lungs - 2025-12-11

Sarah Warsi will defend her Ph.D. thesis on the 4th of October 2022. Driven by the desire to improve patient outcomes, she has dedicated the last several years to studying both in the clinic and the lab. During that time, her research efforts have centered on a better understanding of the functionality and fate of blood stem cells to contribute to developing improved clinical therapies for patient

https://www.stemcellcenter.lu.se/article/phd-defence-interview-sarah-warsi - 2025-12-11

The Royal Swedish Academy of Sciences has elected two new members of the Academy’s class for medical sciences. One of them is Malin Parmar, Professor of Cellular Neuroscience at Lund University, and Principal Investigator at Lund Stem Cell Center. Together with her research group, Malin Parmar has conducted several groundbreaking studies on stem cells that have led to the development of new treatm

https://www.stemcellcenter.lu.se/article/malin-parmar-elected-royal-swedish-academy-sciences - 2025-12-11

On 14 October 2022, Jessica Giacomoni will defend her Ph.D. thesis. With the ultimate goal to develop a possible, future alternative to cell transplantation for the treatment of neurodegenerative disorders, her research efforts have focused on the direct conversion of human glial cells into therapeutic neurons directly within the brain. Here, she tells us about future possibilities with this emerg

https://www.stemcellcenter.lu.se/article/turning-glia-neurons-inside-brain-phd-interview-jessica-giacomoni - 2025-12-11

Ouyang Yuan defends her Ph.D. thesis on 14 October 2022. As a medical student with a longstanding interest in blood malignancies, her research has focused on better understanding the development of a specific type of blood cancer, acute myeloid leukemia (AML). The hope is that these findings will help lead to a better understanding of AML and future treatments that can one day prevent, delay, or c

https://www.stemcellcenter.lu.se/article/placing-acute-myeloid-leukemia-under-microscope-phd-interview-ouyang-yuan - 2025-12-11

Skåne University Hospital, Lund University and Leiden University Medical Center will collaborate to develop research, education and care delivery in the field of ATMPs (Advanced Therapy Medicinal Products). That is the essence of a Memorandum of Understanding that was signed at the SciLifeLab near Stockholm on Wednesday 12 October, during the state visit of the Dutch Royal couple in Sweden. During

https://www.stemcellcenter.lu.se/article/international-collaboration-strengthen-development-atmps - 2025-12-11

An investigational stem cell-based therapy for the treatment of Parkinson’s Disease, STEM-PD, has been given regulatory approval for a Phase I/IIa clinical trial. Ethical approval of the trial has already been obtained from the Swedish Ethics Review Authority, and the STEM-PD team, led from Lund University in Sweden, is thereby ready to proceed with the trial. “We are excited and looking forward t

https://www.stemcellcenter.lu.se/article/swedish-medical-products-agency-grants-approval-clinical-study-new-stem-cell-based-parkinsons - 2025-12-11