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Principal Investigator Christopher Douse and the Epigenetics and Chromatin Dynamics research group join Lund Stem Cell Center, where they will explore the control and influence of ‘genomic dark matter’ in human brain development. Motivated by fundamental questions about mechanisms underpinning human disease, Christopher Douse’s research interests have gradually shifted from the natural sciences to

https://www.stemcellcenter.lu.se/article/new-research-group-led-christopher-douse-joins-lund-stem-cell-center - 2025-10-01

On 20 December, 2022 Kristijonas Zemaitis will defend his Ph.D. thesis. With the goal to improve the availability of human hematopoietic stem cells (HSCs) for the treatment of patients with blood disorders, he has spent the past several years working to better understand HSCs and how they are regulated to one day propagate these stem cells in the lab for therapeutic purposes. In this interview, we

https://www.stemcellcenter.lu.se/article/unravelling-mechanisms-blood-stem-cell-expansion-phd-interview-kristijonas-zemaitis - 2025-10-01

Earlier this fall, the Swedish Cancer Foundation (Cancerfonden) distributed 133 million SEK to 41 cancer researchers at Lund University. Nearly a quarter of this - 28 million SEK - has been awarded to 11 researchers from Lund Stem Cell Center, funding translational research which seeks to advance cancer diagnosis, treatment, and prevention. Isabella Artner, Associate Professor, is among the 11 res

https://www.stemcellcenter.lu.se/article/funding-basic-science-advance-cancer-research-cancerfonden-distributes-28-million-sek-lund-stem-cell - 2025-10-01

Researchers at Lund University and Lund Stem Cell Center have generated human mini bones in the lab which mirror the composition and function of human bone. The results published in Science Translational Medicine detail this step toward the future development of patient-tailored, personalized models of bone cancers and tumors. On average, the adult body consists of 206 bones. Housed in the center

https://www.stemcellcenter.lu.se/article/toward-personalized-approach-study-and-treatment-bone-cancers - 2025-10-01

Lund Stem Cell Center researchers from Lund University and Skåne University Hospital have uncovered a way to impair the growth and progression of glioblastoma tumor cells - the most aggressive form of brain cancer. The study, published in Molecular Cancer Therapeutics, shows it is possible to transform these cancer cells into cells that resemble normal, mature astrocytes. Nearly half of all cancer

https://www.stemcellcenter.lu.se/article/reprogramming-cancer-cells-impair-glioblastoma-growth - 2025-10-01

Professor Filipe Pereira, researcher at the Lund Stem Cell Center, is the principal investigator of one of two innovation-driven research initiatives at Lund University to receive a Proof of Concept Grant from the European Research Council (ERC). The goal of the project is to harness a new technology to enable powerful and targeted therapies for the treatment of solid tumors. Since receiving the E

https://www.stemcellcenter.lu.se/article/erc-grant-supports-new-innovative-advancements-immunotherapy-research - 2025-10-01

While it is well known that men and women have different health needs, have you ever considered why? The Systems Immunology research group, led by Camila Consiglio, has. Together, Lund Stem Cell Center’s newest members are working to uncover whether the answer lies in the differences between the female and male immune systems. “At the heart of our research is the question: how can we understand th

https://www.stemcellcenter.lu.se/article/unveiling-gender-gap-immunity-camila-consiglio-joins-lund-stem-cell-center - 2025-10-01

Jiao Dong defended her Ph.D. thesis on the 8th of February 2023. Inspired by the memory of patients she met during her time as a student studying oral surgery in China, she has spent the past four years researching a regenerative medicine strategy that can be used to repair the function of the salivary gland. In this interview, we learn more about her innovative research efforts, the inspiration b

https://www.stemcellcenter.lu.se/article/bioengineering-and-cell-derived-strategies-salivary-gland-regeneration-phd-interview-jiao-dong - 2025-10-01

Last month, Ella Quist defended her Ph.D. thesis. After beginning her research journey as a master’s student within our Ph.D. Preparatory Program, she dedicated the last several years to developing more efficient methods that can be used to generate functional and mature astrocytes for disease modeling of neurological disorders. In this interview, we learn more about her efforts to facilitate futu

https://www.stemcellcenter.lu.se/article/generating-human-astrocytes-disease-modeling-phd-interview-ella-quist - 2025-10-01

During the fetal stage, a number of so-called cell programs run that are vital to the development of the fetus. In a study published in Cell Reports, researchers from Lund Stem Cell Center at Lund University demonstrate that one of these fetal programs appears to protect against acute myeloid leukaemia (AML). “We have used an experimental mouse model that always results in this type of leukaemia.

https://www.stemcellcenter.lu.se/article/new-insights-fetal-development-may-protect-against-leukaemia - 2025-10-01

Hani Alsafadi defended his Ph.D. thesis on the 13th of February, 2023. With a longstanding interest in biomedical research and a passion for better understanding one of the least regenerative organs in the body, the lung, he has spent the past four years helping to uncover some of the mechanisms that may drive a lung disease currently without a cure, idiopathic pulmonary fibrosis. In this intervie

https://www.stemcellcenter.lu.se/article/exploring-role-yap-and-taz-lung-epithelium-phd-interview-hani-alsafadi - 2025-10-01

​​​​​​​Did you know that about 70% of rare diseases begin in childhood? How about that 1 in 5 cancers are considered a rare disease? Or that nearly three-quarters of all rare diseases are genetic diseases? With more than 6,000 rare diseases known to impact the lives of an estimated 300 million people around the world – rare diseases are all too common. Limited knowledge of these diseases often res

https://www.stemcellcenter.lu.se/article/shining-spotlight-rare-disease-research - 2025-10-01

On 13th of February, a transplant of stem cell-derived nerve cells was administered to a person with Parkinson’s at Skåne University Hospital, Sweden. The product has been developed by Lund Stem Cell Center researchers at Lund University and it is now being tested in patients for the first time. The transplantation product is generated from embryonic stem cells and functions to replace the dopamin

https://www.stemcellcenter.lu.se/article/first-patient-receives-milestone-stem-cell-based-transplant-parkinsons-disease - 2025-10-01

On 03 March 2023, Jenny Mattsson defended her Ph.D. thesis. With the goal to broaden the availability of antibody-based drugs for patients with cancer and other diseases, she has spent the past several years working to develop new methods that can be used to identify new antibodies and antibody targets. In this interview, we learn more about her research, how she has simultaneously juggled doing a

https://www.stemcellcenter.lu.se/article/new-methods-phenotypic-antibody-discovery-phd-interview-jenny-mattsson - 2025-10-01

Have you ever wondered what it takes to grow a brain in a petri dish or how scientists use viruses to fight genetic diseases? These are just some of the fascinating topics explored on UniStem Day 2023 at Lund Stem Cell Center in Sweden. On 10 March 2023, more than 220 high school students from across Sweden's southern Skåne region arrived at Lund Stem Cell Center at Lund University for a day of le

https://www.stemcellcenter.lu.se/article/inspiring-tomorrows-scientists - 2025-10-01

There is a large carton of chicken eggs on the bench in Sofie Mohlin's laboratory. They have been delivered during the morning and soon they will be placed in the 37-degree heat of the incubator so that the embryo can develop. Already 42 hours after fertilization, researchers can begin their experiments to study how neuroblastoma develops. Sofie Mohlin is an Associate Professor in Molecular Physio

https://www.stemcellcenter.lu.se/article/eggs-can-help-us-understand-neuroblastoma - 2025-10-01

Researchers at Lund Stem Cell Center and Lund University's Faculty of Medicine have determined a novel mechanism linking the metabolism of ribonucleic acids, RNA, to the development of leukemia in myelodysplastic syndrome patients, MDS. In a study published in the Molecular Cell journal, they explain what makes hematopoietic stem cells acquire malignant traits in cancer. RNA splicing is a major ne

https://www.stemcellcenter.lu.se/article/what-makes-blood-stem-cells-transform-regulation-rna-splicing-may-be-answer - 2025-10-01

For two decades, researchers at Lund University's strategic research area, Lund Stem Cell Center, have focused on developing and refining stem cell research to improve human health. Now that the 20th anniversary is approaching, it is time to reflect on the progress made and the possibilities that researchers see for stem cell research in the future. Stem cells can make any inventor green with envy

https://www.stemcellcenter.lu.se/article/vision-reality-20-years-cutting-edge-research-lund-stem-cell-center - 2025-10-01

Researchers from Lund Stem Cell Center are coming together with colleagues across Lund University to shape the future of healthcare. A new University-wide seed funding initiative seeking to support emerging research topics that benefit society will see interdisciplinary teams of neuroscience, medicine, and biotechnology researchers attempt to develop new, innovative, patient-specific disease model

https://www.stemcellcenter.lu.se/article/interdisciplinary-teams-lund-university-unite-develop-patient-tailored-disease-models - 2025-10-01

A recent study conducted by researchers at Lund University's Lund Stem Cell Center, and published in the Journal of Biological Chemistry, has unraveled the intricate inner workings of UM171—a molecule known for its ability to support blood stem cells. These findings not only highlight UM171's potential as a therapeutic solution for various diseases, including cancer, but also provide new insights

https://www.stemcellcenter.lu.se/article/decoding-inner-workings-blood-stem-cell-boosting-molecule - 2025-10-01