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What makes blood stem cells transform? Regulation of RNA splicing may be an answer

Researchers at Lund University Faculty of Medicine have determined a novel mechanism linking the metabolism of ribonucleic acids, RNA, to the development of leukemia in myelodysplastic syndrome patients, MDS. In a study published in the Molecular Cell journal, they explain what makes hematopoietic stem cells acquire malignant traits in cancer. RNA splicing is a major nexus of gene expression regul

https://www.medicine.lu.se/article/what-makes-blood-stem-cells-transform-regulation-rna-splicing-may-be-answer - 2025-11-05

ERC Advanced Grant for Alzheimer's Research

Three researchers at Lund University in Sweden, all with a long list of significant research credentials, have been awarded the ERC Advanced Grant worth EUR 2.5 million each to further develop and advance their research projects. One of these researchers is neuroscientist Oskar Hansson, who will use blood tests for rapid screening of drugs in the treatment of Alzheimer’s disease. The European Rese

https://www.medicine.lu.se/article/erc-advanced-grant-alzheimers-research - 2025-11-05

Obstetricians more emotionally stable than most

Swedish obstetricians and gynecologists are noticeably more emotionally stable and conscientious compared to the majority of the Swedish population. Based on the doctors' personalities, their decision-making styles differ in emergency situations. The research study from Lund University is now published in Scientific Reports. Personality is usually summarized in five traits - the so-called "big fiv

https://www.medicine.lu.se/article/obstetricians-more-emotionally-stable-most - 2025-11-05

Revealed: Molecular “superpower” of antibiotic-resistant bacteria

A species of ordinary gut bacteria that we all carry flourishes when the intestinal flora is knocked out by a course of antibiotics. Since the bacteria is naturally resistant to many antibiotics, it causes problems, particularly in healthcare settings. A study led from Lund University in Sweden now shows how two molecular mechanisms can work together make the bacterium extra resistant. “Using this

https://www.medicine.lu.se/article/revealed-molecular-superpower-antibiotic-resistant-bacteria - 2025-11-05

Cocktail of modified antibodies provides strong effect against SARS-CoV-2

Is it possible to improve the antibodies that the body produces to fight SARS-CoV2? In a study led by researchers from Lund University in Sweden, this was investigated by redesigning antibodies and combining them against the virus. The modified antibodies have been tested in human cells and with mice. Many antibodies used to treat covid infection during the pandemic have been so-called neutralizin

https://www.medicine.lu.se/article/cocktail-modified-antibodies-provides-strong-effect-against-sars-cov-2 - 2025-11-05

Hello there, Anil Seth…

Almost 14 million viewers have watched Anils Seth’s TED Talk “Your brain hallucinates your conscious reality”. In the beginning of May, he visits Lund University and Neuroscience Day to give this year's prestigious Segerfalk lecture. We meet on zoom for a conversation about AI, the mystery of consciousness and – of course – to find out what he knew about Sweden. … how would you explain consciousne

https://www.medicine.lu.se/article/hello-there-anil-seth - 2025-11-05

Understanding the sensitivities of body and mind: Open lecture with the 2023 honorary doctors of the Faculty of Medicine

A Nobel laureate and a pioneer have been appointed honorary doctors 2023 at our faculty. On May 24, they offer their insights into the sensitivities of body and mind in an open lecture. In this lecture you will hear the 2023 honorary doctors of the Faculty of Medicine, Nobel laureate professor David Julius and professor Rita Charon each talk about their research and what it has taught them about t

https://www.medicine.lu.se/article/understanding-sensitivities-body-and-mind-open-lecture-2023-honorary-doctors-faculty-medicine - 2025-11-05

Superstars coming to Lund for drug and pharmaceutical symposium

Several Nobel laureates, renowned scientists, and successful biotech entrepreneurs are coming to Lund in May to participate in the Lund Spring Symposium, an international symposium on drug research. Medications are the physician's primary tool when treating their patients, and understanding how drugs work is fundamental to being a good doctor, according to Lars Grundemar, adjunct professor of clin

https://www.medicine.lu.se/article/superstars-coming-lund-drug-and-pharmaceutical-symposium - 2025-11-05

New discoveries about where atherosclerotic plaques rupture can lead to preventive treatments

A common cause of myocardial infarction and stroke is the rupture of atherosclerotic plaques. The exact location of plaque ruptures has previously been unknown, but now researchers at Lund University have mapped this. The research team has also identified an enzyme, a marker, that they hope will help predict who is at risk of having a myocardial infarction or a stroke due to a ruptured atheroscler

https://www.medicine.lu.se/article/new-discoveries-about-where-atherosclerotic-plaques-rupture-can-lead-preventive-treatments - 2025-11-05

Kicking kidney cancer

What happens when you mix a group of tumor biology researchers with software developers and AI researchers? Hopefully, with the help of AI, they can connect a multitude of data that leads to new treatments for kidney cancer – that's at least what the researchers in the EU-project KATY envision. But first, they need to find a common language that all professional groups understand. – It's a challen

https://www.medicine.lu.se/article/kicking-kidney-cancer - 2025-11-05

Alarming antibiotic resistance discovered in war-torn Ukraine

Researchers led by Lund University in Sweden have assisted microbiologists in Ukraine in investigating bacterial resistance among the war-wounded patients treated in hospitals. The results, which were recently published in The Lancet Infectious Diseases, reveal that many of the patients were affected by bacteria that exhibited an extremely high level of antibiotic resistance. “I am quite thick-ski

https://www.medicine.lu.se/article/alarming-antibiotic-resistance-discovered-war-torn-ukraine - 2025-11-05

Lewy body disease can be detected before symptoms

Lewy body disease is the second most common neurodegenerative disease after Alzheimer's disease. A research group from Lund University has now shown that the disease can be detected before symptoms appear, using a spinal fluid test. The studies are published in Nature Medicine, where the researchers also demonstrate that reduced sense of smell is strongly linked to Lewy body disease even before ot

https://www.medicine.lu.se/article/lewy-body-disease-can-be-detected-symptoms - 2025-11-05

Gut and mouth bacteria give researchers new clues about atherosclerosis

What is the link between atherosclerosis and gut and mouth bacteria? Researchers behind a large new study have found several new connections. In the long term, this knowledge can benefit people with type 2 diabetes, a group with an increased risk of developing atherosclerosis. In atherosclerosis, fat and calcium have accumulated in the artery walls over time, forming so called atherosclerotic plaq

https://www.medicine.lu.se/article/gut-and-mouth-bacteria-give-researchers-new-clues-about-atherosclerosis - 2025-11-05

Electrotherapy without surgery

Researchers at Lund and Gothenburg Universities have successfully developed temporary, organic electrodes that can be seamlessly integrated into biological systems. The method, now published in Nature Communications, opens up a future where bioelectronics can be implanted in and removed from the body without surgery. Electrotherapy is a medical treatment method that uses electrical currents to sti

https://www.medicine.lu.se/article/electrotherapy-without-surgery - 2025-11-05

AI-supported mammography screening is found to be safe

Mammography screening supported by artificial intelligence (AI) is a safe alternative to today’s conventional double reading by radiologists and can reduce heavy workloads for doctors. This has now been shown in an interim analysis of a prospective, randomised controlled trial, which addressed the clinical safety of using AI in mammography screening. The trial, led by researchers from Lund Univers

https://www.medicine.lu.se/article/ai-supported-mammography-screening-found-be-safe - 2025-11-05

Link between selenium deficiency and heart failure

A research study at Lund University shows that there is an association between selenium deficiency and an increased risk of developing heart failure. The risk is twice as high for individuals with low selenium levels. Heart failure is a common condition affecting 250 000 Swedes. In heart failure, the heart cannot pump enough blood into the body, and the disease is associated with a poor prognosis.

https://www.medicine.lu.se/article/link-between-selenium-deficiency-and-heart-failure - 2025-11-05

How psychedelic drugs affect a rat’s brain

Researchers at Lund University have developed a technique for simultaneously measuring electrical signals from 128 areas of the brain in awake rats. They have then used the information to measure what happens to the neurons when the rats are given psychedelic drugs. The results show an unexpected and simultaneous synchronisation among neurons in several regions of the brain. In light of the develo

https://www.medicine.lu.se/article/how-psychedelic-drugs-affect-rats-brain - 2025-11-05

Positive metabolic effects of gastric bypass disappear quickly

A new study from Lund University in Sweden raises questions about the efficacy of bariatric operations involving gastric bypass. The results show that the biggest metabolic changes happened directly after surgery. Just a year after the operation, the concentration of metabolites and fats had returned to almost the same levels as before the procedure. Previous research has shown that the majority o

https://www.medicine.lu.se/article/positive-metabolic-effects-gastric-bypass-disappear-quickly - 2025-11-05

EU funding for killer cells that fight cancer

As certain tumor cells are able to conceal themselves in the body, it often means that patients with aggressive cancers experience a recurrence of the cancer after treatment. By programming genetically modified killer immune cells to seek and destroy the hiding tumor cells and tumor stem cells, it is hoped that we can develop more effective treatment options. An international research project, wit

https://www.medicine.lu.se/article/eu-funding-killer-cells-fight-cancer - 2025-11-05

Breast cancer study altered guidelines in Sweden

BRCA1 and BRCA2 are well-known breast cancer genes associated with a significantly increased risk of hereditary breast and ovarian cancer. However, there are an additional eleven genes associated with elevated risk for these types of cancer. A multi-year Swedish study now reveals that the proportion of women with genetically confirmed hereditary breast cancer doubled by including all genes in the

https://www.medicine.lu.se/article/breast-cancer-study-altered-guidelines-sweden - 2025-11-05