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Comprehensive epigenomic studies in multiple myeloma (MM) that unravel the connections between major epigenetic regulators, their intertwined collaboration and the potential of combinatorial targeting remain limited. Utilizing ChIP-seq, ATAC-seq, RNA-seq, and DNA methylation (DNAme) data, we generated whole-genome chromatin annotations from normal plasma cells and MM patients, revealing epigenomic

This article exposes the invisible sand that underpins Copenhagen’s transformation from fishing village to global city. By “following sand,” we trace how planetary material flows sustain urban expansion while entangling the city in processes of capital accumulation, class restructuring, and ecological degradation. Drawing on Science and Technology Studies (STS) approaches, yet situating them firml

Background and purpose: Angiosarcoma (AS), a rare and highly malignant tumour, can manifest spontaneously (primary AS, pAS) or secondary to previous radiation, exposure to chemical agents or Stewart-Treves syndrome (secondary AS, sAS). The aim of this study was to characterise the clinical presentation, management, treatment and outcome—including local recurrence, metastasis and overall survival—a

When it comes to random walk on the integers Z, the arguably first step of generalization beyond simple random walk is the class of one-sidedly continuous random walk, where the stepsize in only one direction is bounded by 1. Moreover, the time until state 0 is hit by left-continuous random walk on Z started at 1 has a direct connection to the total progeny in branching processes. In the analysis

Försök att beskriva och rekonstruera omständigheterna kring Carl Johan Tornbergs (1807-1877) utnämning till och installation som professor i österländska språk 1850.

Ethnographic methods can advance our knowledge of a setting through its documents as well as help the researcher to grasp a document in its setting. This chapter contests the idea that the study of documents only refers to close analyses of text. Taking pictures of documents, asking about documents, and observing what people do with documents are approaches that can answer sociologically significa

Background: During the transition to parenthood, fathers face psychosocial changes that are accompanied by uncertainty and insecurity. Feelings of insecurity may affect fathers’ experiences of pregnancy and childbirth, adjustment to the paternal role, and bonding with their child. There is a need to better understand fathers’ experiences of security and the causal and constitutional factors involv

Under de första åren av 2000-talet betraktades ”den galopperande sjukfrånvaron” som en av de absolut viktigaste frågorna i den välfärdspolitiska debatten. En mängd aktörer förde fram olika (och ibland konkurrerande) uppfattningar om problemet, dess orsaker och tänkbara lösningar. Sådana skeenden brukar kallas problemdefinieringsprocesser och har stor betydelse, både för vilka frågor som hamnar på

This chapter is about social work and prostitution, understood as a relation in which sexual acts are exchanged for money or other material or immaterial resources. The aim is to understand different approaches in social work by linking up to a policy-process perspective. As any social phenomenon, prostitution can be framed differently as a policy problem. The chapter is structured around three di

The project offers a study of German-Jewish thought by examining Walter Benjamin’s notion of law through the interpretive framework of the Talmud. The widely recognised locus of Benjamin's discussion of law is his essay Toward the Critique of Violence. In his later essays on Kafka, however, Benjamin develops an alternative to the familiar negative notion of law found in the Critique, a development

“Honestly waste” is a collaborative project between Swedese, a pioneer in Swedish furniture design, and Malmö Upcycling Service (M.U.S), a design studio dedicated to transforming industrial waste into valuable products. The partnership focuses on exploring how Swedese’s production waste—comprising wood, leather, fabric, and metal—can be reimagined into functional, aesthetically appealing, and mark

I takt med ett mer extremt klimat till följd av global uppvärmning förväntas kusterna världen över bli allt mer utsatta då stormars frekvens och intensitet beräknas öka. För att kustnära infrastruktur och personlig egendom ska kunna stå emot dessa intensifierade belastningar behöver stora delar av världens kustskydd rustas upp. För att tillämpa adekvat dimensionering av dessa faciliteter behöver kThe aim of this masters dissertation is to investigate how problems that includes fluids can be solved numerical through FE-analysis. The problem at hand is to predict the impact force implied by breaking ocean waves on vertical coastal structures. The importance that coastal areas has on human society both from a perspective of economy, infrastructure and recreation are indubitable. Furthermore,