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Heterozygous FA2H mutations in autism spectrum disorders

Background Widespread abnormalities in white matter development are frequently reported in cases of autism spectrum disorders (ASD) and could be involved in the disconnectivity suggested in these disorders. Homozygous mutations in the gene coding for fatty-acid 2-hydroxylase (FA2H), an enzyme involved in myelin synthesis, are associated with complex leukodystrophies, but little is known about the

Prime Rigid Graphs and Multidimensional Scaling with Missing Data

In this paper we investigate the problem of embedding a number of points given certain (but typically not all) inter-pair distance measurements. This problem is relevant for multi-dimensional scaling problems with missing data, and is applicable within anchor-free sensor network node calibration and anchor-free node localization using radio or sound TOA measurements. There are also applications wi

Talk on Musical Interpretation — Visual Tools for Perceived Dynamics and Points of Gravity

Typical for Western classical music is the process of interpreting and conveying a written score into sounding music. However, sometimes the communication of musical issues between musicians may be experienced as aggravating. In educational contexts in a broad sense, it might be advantageous if this communication could be facilitated, for example, by using visual illustrations as a complement to t

Lower Cretaceous Mesoeucrocodylians from Scandinavia (Denmark and Sweden)

The crocodyliform faunas of the lowermost Cretaceous Rabekke and Jydegard Formations on the Baltic island of Bornholm, Denmark, and the Annero Formation of Skane, southernmost Sweden, are represented by isolated teeth, osteoderms, and vertebrae. The rich Berriasian assemblage of the Rabekke Formation includes at least three distinctive taxa: Bernissartia sp., Theriosuchus sp., and Goniopholis sp.,

The leukemia associated nuclear corepressor ETO homologue genes MTG16 and MTGR1 are regulated differently in hematopoietic cells

Background: MTG16, MTGR1 and ETO are nuclear transcriptional corepressors of the human ETO protein family. MTG16 is implicated in hematopoietic development and in controlling erythropoiesis/megakaryopoiesis. Furthermore, ETO homologue genes are 3'participants in leukemia fusions generated by chromosomal translocations responsible of hematopoietic dysregulation. We tried to identify structural and

Charged-particle multiplicity measurement in proton-proton collisions at root s=7 TeV with ALICE at LHC

The pseudorapidity density and multiplicity distribution of charged particles produced in proton-proton collisions at the LHC, at a centre-of-mass energy root s = 7 TeV, were measured in the central pseudorapidity region vertical bar eta vertical bar < 1. Comparisons are made with previous measurements at root s = 0.9 TeV and 2.36 TeV. At root s = 7 TeV, for events with at least one charged partic

Shockley-Queisser Detailed Balance Efficiency Limit for Nanowire Solar Cells

III-V semiconductor nanowire arrays show promise as a platform for next-generation solar cells. However, the theoretical efficiency limit for converting the energy of sunlight into electrical energy in such solar cells is unknown. Here, we calculate through electromagnetic modeling the Shockley-Queisser efficiency limit for an InP nanowire array solar cell. In this analysis, we calculate first fro

A model-based methodology for the analysis and design of atomic layer deposition processes-Part II: Experimental validation and mechanistic analysis

This paper demonstrates the experimental validation and mechanistic analysis of the continuous cross-flow atomic layer deposition (ALD) reactor model developed in the first article of this series (Holmqvist et al., in press). A general nonlinear parameter estimation problem was formulated to identify the kinetic parameters involved in the developed ALD gassurface reaction mechanism, governing ZnO

Scaling and Gating Attosecond Pulse Generation

Popular Abstract in English This thesis is concerned with the efficient generation of ultra-short light pulses, far beyond the visible spectral range. Such light pulses can reach durations below 100 attoseconds, where one attosecond is one billionth of a billionth of a second. Why do we want to generate such extreme light pulses? Our knowledge of basic processes in physics and chemistry is to a High-order harmonic generation (HHG) provides the basis for attosecond light sources delivering coherent pulses in the extreme ultraviolet spectral region. Such light sources are employed for a variety of applications within imaging, attosecond spectroscopy, and high-precision frequency metrology. However, the rather low efficiency of the HHG process, which implies a limited pulse energy and repet

Sonographic prediction of vaginal delivery in prolonged labor: a two-center study

Objective To investigate whether head-perineum distance (HPD) measured by transperineal ultrasound is predictive of vaginal delivery and time remaining in labor in nulliparous women with prolonged first stage of labor and to compare the predictive value with that of angle of progression (AoP). Methods This was a prospective observational study at Stavanger University Hospital, Norway and Addenbroo

Two-Dimensional Electronic Spectroscopy Reveals Ultrafast Energy Diffusion in Chlorosomes.

Chlorosomes are light-harvesting antennae that enable exceptionally efficient light energy capture and excitation transfer. They are found in certain photosynthetic bacteria, some of which live in extremely low-light environments. In this work, chlorosomes from the green sulfur bacterium Chlorobaculum tepidum were studied by coherent electronic two-dimensional (2D) spectroscopy. Previously unchara

Three-Dimensional Simulation of Nanoindentation Response of Viral Capsids. Shape and Size Effects

The nanoindentation response of empty viral capsids is modeled using three-dimensional finite element analysis. Simulation with two different geometries, spherical and icosahedral, is performed using the finite element code Abaqus. The capsids are modeled as nonlinear Hookean elastic, and both small and large deformation analysis is performed. The Young's modulus is determined by calibrating the f

Female hairdressers - Respiratory symptoms, mechanisms, and health-related quality of life and their views on the work environment

Popular Abstract in Swedish Frisöryrket har en lång historia av stolta yrkesutövare, men frisörer arbetar i en komplex arbetsmiljö, där de utsätts för olika risker, inte bara luftvägsbesvär, utan även handeksem, muskelrelaterade besvär, stress, och ögonbesvär. I Sverige är 85 - 90 % av frisörerna kvinnor, varav de flesta är egenföretagare antingen som ensamägare till en salong eller tillsammans meLittle is known of respiratory symptoms in female hairdressers, and of the impact on the health-related quality of life (HRQoL), nor of knowledge of their own views on preventive work. The aim of this thesis was to examine the occurrence of asthma, symptoms and mechanism of bleaching-associated nasal symptoms, the effects on HRQoL and how young hairdressers reason about the work environment. A m

3D-fastigheter och ägarlägenheter – ett nytt och spännande område för exjobb

En studie har gjorts av samtliga exjobb om 3D-fastigheter och ägarlägenheter gjorda sedan slutet av 1990-talet. Ämnet har lockat 135 exjobbare på 17 olika universitet och högskolor i Sverige. De två nya rättsobjekten passar utmärkt för studier inom rättsvetenskap, fastighetsvetenskap, fysisk planering och andra ingenjörsämnen, ekonomi mm. Kunskap finns tillgänglig, i exjobben och hos alla dessa ny

Mammonist Capitalism – Ubiquity, Immanence, Acceleration. And the Social Consequences

This essay attempts at a general understanding of contemporary capitalism and some of its social and mental consequences. It works through combinations and variations of concepts from classical and contemporary social theory. Some key concepts are Mammonism, acceleration, ubiquity, self-dynamics, precariat, inertia, conformity, flexibility, specter of uselessness. The text refers to classical mode

Assessment of Regional Progression of Pulmonary Emphysema With CT Densitometry

Background: Lung densitometry is an effective method to assess overall progression of emphysema, but generally the location of the progression is not estimated. We hypothesized that progression of emphysema is the result of extension from affected areas toward less affected areas in the lung. To test this hypothesis, a method was developed to assess emphysema severity at different levels in the lu

Asymmetric trends and European monetary policy in t he Post-Bretton Woods Era

In public debate the crisis of the eurozone has been laid on the footstep of imprudent government finance. This paper argues that the depth and longevity of the crisis instead is due to ‘asymmetric trends’ that are inherent in the eurozone. We show this, first, by a test of the ‘one-size-fits-all’ ECB monetary policy. The results provide an estimate of how ECB at the same time fuelled some ‘bubble