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The brain has a never-ending internal activity, whose spatiotemporal evolution interacts with external inputs to constrain their impact on brain activity and thereby how we perceive them. We used reproducible touch-related spatiotemporal sensory inputs and recorded intracellularly from rat (Sprague-Dawley, male) neocortical neurons to characterize this interaction. The synaptic responses, or the s

In this chapter, Whalen and Kijne critically engage with two game-based approaches—serious games and gamification—and how they can be used to support sustainable innovation. Game-based approaches have been increasingly used for purposes beyond pure entertainment, and a variety of examples from within the field of sustainability are presented. The authors discuss both the benefits and limitations o

Bok recension av Ninna Edgardhs bok Diakonins kyrka.

The Soma and Neurite Density Imaging (SANDI) three-compartment model was recently proposed to disentangle cylindrical and spherical geometries, attributed to neurite and soma compartments, respectively, in brain tissue. There are some recent advances in diffusion-weighted MRI signal encoding and analysis (including the use of multiple so-called ’b-tensor’ encodings and analysing the signal in the

Conditions experienced during early life can have long-term individual consequences by influencing dispersal, survival, recruitment and productivity. Resource allocation during development can have strong carry-over effects onto these key parameters and is directly determined by the quality of parental care. In the black sparrowhawk (Accipiter melanoleucus), a colour-polymorphic raptor, parental m

Background: Kidney biopsy registries all over the world benefit research, teaching and health policy. Comparison, aggregation and exchange of data is however greatly dependent on how registration and coding of kidney biopsy diagnoses are performed. This paper gives an overview over kidney biopsy registries, explores how these registries code kidney disease and identifies needs for improvement of c

Exposure to endocrine disrupting chemicals (EDCs) may impact early growth, although information is limited on exposure to combination of multiple EDCs. We aimed to evaluate the effect of prenatal exposure to EDC mixtures on birthweight z-scores and childhood weight trajectories. Twenty-six proven and suspected EDCs, were analyzed in prenatal urine and blood samples from 1118 mothers participating

Monitoring and early detection of emerging infectious diseases in wild animals is of crucial global importance, yet reliable ways to measure immune status and responses are lacking for animals in the wild. Here we assess the usefulness of bio-loggers for detecting disease outbreaks in free-living birds and confirm detailed responses using leukocyte composition and large-scale transcriptomics. We s

Recent advances in metagenomic technology and computational prediction may inadvertently weaken an individual’s reasonable expectation of privacy. Through cross-kingdom genetic and metagenomic forensics, we can already predict at least a dozen human phenotypes with varying degrees of accuracy. There is also growing potential to detect a “molecular echo” of an individual’s microbiome from cells dep

Satisfying the mobile traffic demand in next generation cellular networks increases the cost of energy supply. Renewable energy sources are a promising solution to power base stations in a self-sufficient and cost-effective manner. This paper presents an optimal method for designing a photovoltaic (PV)-battery system to supply base stations in cellular networks. A systematic approach is proposed f

Background: Urinary tract infections (UTIs) affect around 20% of the male population in their lifetime. The incidence of UTIs in men in the community is 0.9–2.4 cases per 1000 aged <55 years and 7.7 per 1000 aged ≥85 years. Aim: To evaluate the outcomes of randomised controlled trials (RCTs) comparing the effectiveness of different antimicrobial treatments and durations for uncomplicated UTIs in a

A relativistic transient absorption theory is derived, implemented and validated within the dipole approximation based on the time-dependent Dirac equation. In the non-relativistic limit, it is found that the absorption agrees with the well established non-relativistic theory based on the time-dependent Schrödringer equation. Time-dependent simulations have been performed using the Dirac equation

I discuss the dilution of responsibility of action and the idea of a symmetrical relationship between artefacts and humans. In doing so, I argue that meaning making is an activity unilaterally performed by agents, leading to an asymmetrical relationship between agents and artefacts. Therefore, the study of the one who is responsible for the action, the meaning-maker (with the capability to act) is

Intellectual property rights (IPR) form an important component for unlocking sustainable innovation. Research highlights both the positive role of IPR in incentivizing sustainable innovation and the negatives, such as delaying diffusion. We review the state-of-art debates on incentivizing sustainable innovations and the role of IPR for sustainable manufacturing industries, summarizing three main d

Displacement ventilation is a proven method of providing conditioned air to enclosed spaces with the aim to deliver good air quality and thermal comfort while reducing the amount of energy required to operate the system. Until now, the practical applications of displacement ventilation have been exclusive to providing ventilation and cooling to large open spaces with high ceilings. The provision o