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Purpose: To estimate the impact upon Health-Related Quality of Life (HRQOL) associated with Type 1 Diabetes Mellitus (T1DM), both with and without associated diabetic complications, for enabling calculation of utility values – Quality of Life Weights (QLW) – for populations with T1DM. Method: Two cohorts from Northern Sweden, one of T1DM patients and one of a general population, were given survey
The restriction modification enzyme system is a vital bacterial defense system against invading phages. Restriction modification system consists of a restriction enzyme and a methyltransferase enzyme that work in a complementary fashion to cut foreign DNA and at the same time methylates and protects host DNA. Recognition site sequence is usually specific for each restriction enzyme. Restriction Re
In this master thesis, the topic of energy storage connected to concentrator photovoltaic power production is assessed. The end goal is to propose the optimal energy storage technology and its sizing, regarding power and energy capacity, for an existing concentrator photovoltaic power plant. The plant is located in the province of Algarve in Portugal, the installed production capacity is 4.5 MW, a
This thesis suggests and tests two methods for categorizing instruments in a musical signal. The first method involves spectral analysis and the magnitude spectrum, analysing the structure of pitches and overtones and how the amplitude of those changes over time. The second method involves cepstrum analysis and especially the, for speech recognition popular method computing the Mel Frequency Cepst
In order to understand how the Pleistocene glacial cycles have influenced the diversification in the Reed Bunting (Emberiza schoeniclus) subspecies complex, we conducted a multilocus phylogeographic study. We analysed DNA sequences from 32 breeding populations, covering the species’ Palearctic distribution, and used population genetics, phylogenetic and coalescent methods to uncover genetic struct
This paper investigates the impact of HIV prevalence on schooling achievement. By associating data of schooling test results, for seven countries in Sub-Saharan Africa, with regional measures of HIV prevalence for 70 different regions, I find evidence that a general increase in HIV prevalence of about 1%, lowers general test score results of about 1% of a standard deviation from the mean. Endogene
Children affected by the multisystem genetic disorder Hutchinson-Gilford Progeria Syndrome look prematurely aged, suffer from elderly-related conditions and die during adolescence due to cardiovascular complications. The cause of the disease is single point gain-of-function mutations in the LMNA gene, which encodes the lamin A and lamin C proteins, major components of the nuclear lamina. These mut
Heart failure is one of the most common reasons for death in the modern society. As the field of tissue engineering is evolving, cardiac patches as treatment for suffering patients holds future promise. However, methods for efficient purification of cardiomyocytes from biopsies are lacking, hindering the development of such solutions. Here a novel method for separation of cardiomyocytes in a micro
The interest of this research lies in the nexus between the state and the individual in providing social care for people searching asylum in Finland. The study explores the experiences of host families involved in offering home accommodation for asylum seekers. More specifically, it aims to understand the subjective role that host families assign to themselves when providing social care for this t
Abstract: This thesis is an anthropological study on how a group of people suffering from Posttraumatic Stress Disorder [PTSD] construct meaning in a community center in Copenhagen. The specific aim of this thesis is to investigate how place can be understood as a factor that plays into well-being and recovery. Based on a case study of a Danish community health center, this study shows how users
Helicobacter pylori is an important pathogen inhabiting the human stomach. H. pylori binds plasminogen, a 90 kDa glycoprotein secreted by liver cells, and utilizes it for enhancing virulence. Surface receptors on the bacteria recognize plasminogen that is then activated into plasmin by host factors. The active plasmin can degrade a range of host proteins including proteins of the extracellular mat
Globalization has led to an increase in competition between places in hopes of attracting mobile capital and investments as well as new inhabitants and tourists. Nature-based tourism has become one of the most steadily growing markets for tourism in Europe. In order for a place to be attractive it has to have a brand that can be constructed depending what sort of resources a place has. A place is
My master degree project started with an open brief, setting out to explore new possibilities within healthcare in relation to the benefits of IoT. By looking at medical trends, cutting edge diagnostic technologies, hypothesis about the future and by interviewing patients and medical personnel a couple of interesting project directions emerged. A decision was made to focus on prevention and one to
Avian malaria parasites can have severe fitness effects on the host although most infections seem to be mild. Some of the avian malaria parasites are host specific and infect specific bird species while others infect a wide range of species. Avian malaria can serve as a natural model system for studies of the effect of environmental change on parasites distribution patterns. The global changes of
Bumblebees and other pollinators are important contributors to the ecosystem service of pollination of wild plants and crops. As in many pollinating insects, their abundance and diversity have declined in recent years, due to loss of natural habitats and fragmentation associated with urbanization and agricultural intensification. However, in urban areas, green space management beneficial to pollin
Body appreciation-unappreciation and body satisfaction-dissatisfaction are in the literature seen as conceptually different, but construct distinction has only been supported using qualitative methods. Because of limits in using Likert-style questionnaires to measure multidimensional constructs, quantitative research has yet to directly demonstrate that it is possible to appreciate the body withou
