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The Fiat-Shamir Zoo : Relating the Security of Different Signature Variants

The Fiat-Shamir paradigm encompasses many different ways of turning a given identification scheme into a signature scheme. Security proofs pertain sometimes to one variant, sometimes to another. We systematically study three variants that we call the challenge (signature is challenge and response), commit (signature is commitment and response), and transcript (signature is challenge, commitment an

Particles with tunable wettability for solid-stabilized emulsions

We demonstrate that the wettability of cosmetic grade, silica-coated titanium dioxide nanoparticles may be tuned by simply soaking them in a cyclic silicone oil. This allows for tuning the type of emulsion that they stabilize, from oil-in-water to water-in-oil. By analyzing the sedimentation of water-in-oil emulsions, the effect of the soaking time (wettability) on drop size and drop-drop interact

Improvement of thermotolerance in Lachancea thermotolerans using a bacterial selection pressure

The use of thermotolerant yeast strains is an important attribute for a cost-effective high temperature biofermentation processes. However, the availability of thermotolerant yeast strains remains a major challenge. Isolation of temperature resistant strains from extreme environments or the improvements of current strains are two major strategies known to date. We hypothesised that bacteria are po

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Influence of sintering temperature on both phase composition and structure of ceramic matrix composites based on cubic boron nitride with binders in a form of Al and the Ti, Cr, V carbides are investigated by methods of physical materials science. As the object of study, three cBN–TiC–Al, cBN–Cr3C2–Al, cBN–VC–Al compositions containing 60% vol. cBN are selected. The composites are obtained by high

Clonal evolution through genetic bottlenecks and telomere attrition : Potential threats to in vitro data reproducibility

Tissue cultures of immortalized human cells, also known as established cell lines, are broadly accessible and cost-efficient tools for biomedical research. We here review potential genetic sources of systematic error in cell line experiments due to clonal evolution in vitro. In particular, the authors highlight alterations in telomere function over prolonged culture and population bottlenecks, res

Targeting peptidylarginine deiminase reduces neutrophil extracellular trap formation and tissue injury in severe acute pancreatitis

Recent evidence suggests that neutrophil extracellular traps (NETs) play an important role in the development of acute pancreatitis (AP). Herein, we examined the role of peptidylarginine deiminase (PAD), which has been shown to regulate NET formation, in severe AP. AP was induced by retrograde of taurocholate infusion into pancreatic duct in C57BL/6 mice. PAD was pharmacologically inhibited using

Occupational balance as described by older workers over the age of 65

Occupational balance promotes health, knowledge about occupational balance among older workers is important. This qualitative study aimed to describe occupational balance among older workers in Sweden. Six focus groups and two individual interviews were conducted with 26 workers, aged 65 years and older. The findings showed that drawing on abilities and resources, a harmonious mix of occupations,

Swedish Version of the Hayling Test : Clinical Utility in Frontotemporal Dementia Syndromes

Objectives: The aim of this study was to assess the psychometric properties of a Swedish version of the Hayling test (HT-S) and its clinical utility in a group of patients with different frontotemporal dementia (FTD) syndromes. Early diagnosis of FTD is a challenge and requires a broad arsenal of assessment methods, neuropsychological tests not the least. The Hayling test assesses executive functi

Correlation of in Vivo [18F]Flortaucipir with Postmortem Alzheimer Disease Tau Pathology

Importance: In Alzheimer disease (AD), tau filaments form neuronal inclusions in neurites (neuropil threads) and in somata (neurofibrillary tangles), and neurite tau pathology constitutes the most common pathology. Positron emission tomography (PET) ligands have been developed to detect in vivo tau pathology in AD. However, the association of AD tau pathology post mortem with in vivo tau PET reten

A prescription for “nature” – The potential of using virtual nature in therapeutics

Many studies suggest that increased exposure to urban greenness is associated with better population health. Accessing nature can in some circumstances, however, be difficult, especially for individuals with mobility constraints. Therefore, a growing body of work is investigating the ways to replace the in vivo experience with forms of “virtual” contact, in order to provide these individuals with

Experimental study of dowel design in the shear plate dowel joint

The shear plate dowel joint (SPDJ) is a novel connection design for use in heavy timber structures. Load transfer between timber members is enabled using a single large diameter dowel and externally glued steel plates. The steel plates are glued to the timber using bond lines of low stiffness and high fracture energy to achieve a uniform shear stress distribution, thus maximizing the load carrying

The complexity of mudstone diagenesis–some insight from the Tøyen Shale, Lower to Middle Ordovician, southern Sweden

The Lower to Middle Ordovician Tøyen Shale in southern Sweden, a biostratigraphically well-dated siliciclastic mudstone unit, shows 18 distinct authigenic cements that include sulfides, carbonates, silicates, clays, and phosphates. Marcasite, sphalerite, galena, and six texturally distinct types of pyrite characterize the sulfides whereas only one type of dolomite and three different generations o

Cartilage Oligomeric Matrix Protein initiates cancer stem cells through activation of Jagged1-Notch3 signaling

Cancer stem cell populations are important for the initiation, progression and metastasis of tumors. The mechanisms governing cancer stem cell control are only partially understood, but activation of the Notch3 pathway plays a crucial role in the maintenance of breast cancer stem cells. Expression of Cartilage Oligomeric Matrix Protein (COMP) in breast cancer cells is correlated with poor survival

Association between semen parameters and chance of fatherhood - a long-term follow-up study

Background: Evaluation of male fertility includes standard semen analysis; however, there is uncertainty about the value of sperm parameters in predicting fertility. Objective: To evaluate the association between semen parameters and fatherhood during a long-time period. Materials and methods: Semen parameters (total sperm count, concentration, motility, and morphology) and sperm DNA fragmentation

The impact of lecture recordings on he student approaches to learning

The impact of lecture recordings on HE student approaches to learning Note-taking as a study-skill amongst students in Higher Education (HE) is acknowledged as a fundamental component of academic success. Intrinsic factors such as cognitive capacity, motivation and epistemological beliefs effect note-taking quantity and quality (e.g. Kiewra, 1985). However, this study looks at the extrinsic influe