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The steady loss - Palynological investigation into the main triggers of changes in vegetation and pastoral activity during the Norse period in southern Greenland

Pastoral farming formed a key element of Norse subsistence strategies in South Greenland but with climatic changes of the Little Ice Age they may have reached their limit. Most recently, studies into hydrological changes across the Norse period (10th-15th century AD) revealed a severe drying trend that was coincident with the Norse demise during the early to mid-15th century AD. This study examine

Recovery Potential in Patients After Cardiac Arrest Who Die After Limitations or Withdrawal of Life Support

Importance: Understanding the relationship between patients' clinical characteristics and outcomes is fundamental to medicine. When critically ill patients die after withdrawal of life-sustaining therapy (WLST), the inability to observe the potential for recovery with continued aggressive care could bias future clinical decisions and research. Objective: To quantify the frequency with which expert

Megafon för människans tidsålder : En kritisk analys av miljöfrågans framställning på Riksidrottsmuseum

The article analyses selected parts of the permanent exhibitions at The National Sports Museum in Stockholm, Sweden, focusing on how environmental issues are presented. The analysis is deepened through theories about museology and the Anthropocene, the age of man, and the ways in which the museum addresses human responsibility and role in critical environmental issues. Through a critical discourse

Phase 1/2a clinical trial of BI-1206, an anti-CD32b (FcγRIIB) antibody, in combination with pembrolizumab in subjects with advanced solid tumors previously treated with anti-PD-1/PD-L1.

2593Background: PD-1 blockade has demonstrated positive anti-tumor activity across multiple tumor types. While the anti-tumoral response can be substantial and even curative, response rates remain low in many cancer types. Long-lasting responses are only observed in a minority of patients, and additional immunotherapeutic alternatives remain limited for patients who fail to respond or initially re

Wolbachia improves the performance of an invasive fly after a diet shift

Polyphagy is an adaptative strategy allowing species to develop and survive on multiple diets. Phytophagous insects can be exposed to sub-optimal resources, as host plants vary in nutritional quality. Some insects may rely on symbiotic bacteria to better utilize less favorable substrates. The invasive fruit fly Drosophila suzukii is a highly successful pest worldwide. The use of ripening and ripe

Fallen fruit : A backup resource during winter shaping fruit fly communities

Fallen fruits provide important feeding and breeding substrates for insects such as Drosophilidae and can be a potential trophic reservoir when usual host fruits become scarce. Recently, two invasive fruit fly species, Drosophila suzukii and Chymomyza amoena, have become established in Europe and are expected to alter existing Drosophilidae communities. In this study, carried out between September

Prostate Cancer Foundation Screening Guidelines for Black Men in the United States

BACKGROUND In the United States, Black men are at highest risk for being diagnosed with and dying from prostate cancer. Given this disparity, we examined relevant data to establish clinical prostate-specific antigen (PSA) screening guidelines for Black men in the United States. METHODS A comprehensive literature search identified 1848 unique publications for screening. Of those screened, 287 studi

Wolbachia in Antarctic terrestrial invertebrates : Absent or undiscovered?

Interactions between a host organism and its associated microbiota, including symbiotic bacteria, play a crucial role in host adaptation to changing environmental conditions. Antarctica provides a unique environment for the establishment and maintenance of symbiotic relationships. One of the most extensively studied symbiotic bacteria in invertebrates is Wolbachia pipientis, which is associated wi

Temperature overrides nutritional cues for optimal oviposition decision in a polyphagous invasive insect

Polyphagous insects rely on multiple cues to choose oviposition sites, including substrate temperature and nutritional quality, which often do not coincide. We examined how females of the invasive fly Drosophila suzukii make oviposition decisions when temperature and nutrition mismatch, and whether infection with the symbiotic bacterium Wolbachia influences these choices. We first quantified femal

Future research in weight bias : What next?

The 2015 Canadian Weight Bias Summit disseminated the newest research advances and brought together 40 experts, stakeholders, and policy makers in various disciplines in health, education, and public policy to identify future research directions in weight bias. In this paper we aim to share the results of the Summit as well as encourage international and interdisciplinary research collaborations i

Winter fleshy-fruited plants are the catalysts for spring populations of an invasive fruit fly

Winter is a critical bottleneck period for many insects and is particularly pivotal for pest species, being a major regulator of their populations. In winter, insect fruit pests such as the invasive fly, Drosophila suzukii, not only have to cope with harsh environmental conditions but also need to find alternative resources when cultivated fruit are scarce. This study aimed to disentangle the rela

Environmental factors driving infestations of a keystone winter fruit by an invasive and a native fruit fly

In temperate regions, most insect species overwinter in diapause while others continue to be active, feed, and possibly reproduce despite adverse climatic conditions. For fruit flies which remain active winter long, the presence of winter-available fruit is crucial for population persistence. This study aimed to disentangle the relative effects of climatic, landscape, and local factors on infestat

High dose chemotherapy in male patients with germ cell cancer : A population-based study by the SWENOTECA group.

Background: Selected patients with advanced germ cell tumors have a poor prognosis. These include patients with brain, bone or liver metastases, very elevated tumor markers or primary mediastinal tumor. High-dose chemotherapy (HDCT) with autologous stem cell support is recommended in the Swedish and Norwegian Testicular Cancer Group (SWENOTECA) guidelines in selected poor risk patients with poor r

Thermal Preference Plasticity in Ectotherms : Integrating Temperature Affinity and Thermoregulation Precision

Thermal preference (Tp) prevents ectotherms from encountering sublethal temperatures. Its plasticity likely modulates the importance of behavioral thermoregulation under changing conditions. While it has been widely recognized that Tp varies across ontogeny, the plasticity level of this trait across life stages is poorly understood. We propose a novel conceptual framework relating two plastic comp

The Importance of Infrastructure and Road Safety Culture for Pedestrian Safety : A Comparison of Three European and Three African Countries

Walking is a primary mode of transport in urban Africa, yet it remains unsafe, challenging, and unpleasant. In contrast, several European countries have implemented systematic policies to promote walking through Safe System principles. This study compares pedestrian safety in three African countries (Tanzania, Ghana, Zambia), with three European countries with excellence in road safety and Safe Sy

Incorporating pollinator movement into connectivity models predicts pollen-mediated gene flow and highlights the importance of regenerating forests in tropical landscapes

Context: Pollen-mediated gene flow is crucial for ecological and evolutionary processes and understanding its disruption by anthropogenic disturbances is essential for conservation. Objectives: In this study, we developed landscape connectivity metrics that incorporated hummingbird movement behaviour to assess how structural (amount and configuration) and functional (species-specific behavioural r

Outcomes of the first global multidisciplinary consensus meeting including persons living with obesity to standardize patient-reported outcome measurement in obesity treatment research

Quality of life is a key outcome that is not rigorously measured in obesity treatment research due to the lack of standardization of patient-reported outcomes (PROs) and PRO measures (PROMs). The S.Q.O.T. initiative was founded to Standardize Quality of life measurement in Obesity Treatment. A first face-to-face, international, multidisciplinary consensus meeting was conducted to identify the key

Molecular phylogenetic analysis and taxonomic reconsideration of Ceropegia hirsuta (Apocynaceae, Asclepiadoideae) reveal a novelty in Thailand, Ceropegia citrina sp. nov., with notes on its pollination ecology

The identity of Ceropegia hirsuta in Thailand has been questioned. Although this plant is quite similar to the original C. hirsuta from India, being entirely hirsute, with yellowish-shaded flowers, a curved, funnel-shaped corolla tube, and broad corolla lobes shorter than the corolla tube, there are several clear differences in morphological traits between the materials collected in Thailand and t