Filtyp
Protein aggregation is a hallmark of several neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease and dementia with Lewy bodies. A common feature of these disorders is the misfolding and aggregation of α-synuclein (α-syn) and amyloid-β (Aβ) proteins into amyloid structures, which disrupt cellular homoeostasis and drive disease progression. While Aβ typically forms extrace
“Right to repair” (R2R) has become an important policy objective in European Union (EU) policy and law. The main objective of R2R is to remove barriers that inhibit consumers from repairing the products they own. The EU has made use of different regulatory frameworks to enforce R2R, most notably product regulation to induce design changes and ensure that spare parts and software updates are availa
This chapter reviews the historical development of the regulation of waste and chemicals in both international law and European Union (EU) law after the 1972 Stockholm Conference as well as some of the subsequent trends and themes. It also highlights the relevant interactions between EU and international law on these issues. The chapter ends with a discussion of how the regulatory frameworks relat
Objective:To evaluate short- and long-term outcomes after modified Stage-I (mStage-I) palliation for hypoplastic left heart syndrome (HLHS).MethodsThis retrospective single-centre study analyzed 128 patients with HLHS treated between 1993 and 2023. Patients were divided into two groups: Era-I (n=36), from 1993 to 2001, who underwent the classic Norwood procedure, and Era-II (n=92), from 2002 to 20
This article traces how Yazidi genocide recognition is reworked across juridico-political domains in Germany, drawing on multi-sited ethnographic fieldwork conducted between August 2025 and February 2026 and analysis of criminal judgments and asylum decisions. It argues that recognition does not operate as a stable legal achievement but takes on shifting meanings as it moves across institutional s
BACKGROUND: The aim of this study was to examine whether a novel semi-automated dataset based on electronic health record documentation can be used for surveillance of central venous catheter-related mechanical complications (failed catheterisation, bleeding, cardiac arrhythmia, pneumothorax and nerve injury) within 24 hours of catheterisation.METHODS: The semi-automated dataset comprised a fully
OBJECTIVES: To investigate utilisation patterns of different types of healthcare in a pre-pandemic and pandemic period, respectively, among children with intellectual disabilities in comparison to their age peers in the general population.STUDY DESIGN: Based on 8 years of register data, we identified 1947 children with intellectual disabilities (ID cohort) and 145 998 children from the general pop
Fenomenet ultra-fast fashion har lett till att klädindustrins miljöpåverkan, och frågan om hur textilindustrin bättre kan regleras, diskuteras allt mer intensivt inom EU. Frankrike ligger i framkant och har redan antagit en lag riktad mot ultra-fast fashion, men även på EU-nivå har ett antal styrmedel börjat införas. Även om det är viktigt att EU:s medlemsländer kan behålla ett visst utrymme för e
Dissolved Organic Carbon (DOC) is a key component of the inland water carbon cycle, playing a critical role in water quality, aquatic ecosystem dynamics, and carbon flux assessments. In this study, we combine Sentinel-2 Multi-Spectral Instrument (MSI) data with in-situ water quality, meteorological, and temporal variables to predict DOC concentrations in Lake Erken, Sweden. Three Machine Learning
Combustion of NH3 with H2 addition can improve the combustion stability. In this study, the laminar burning velocities (LBVs) of NH3/H2/O2/CO2 mixtures were determined under atmospheric pressure and an initial temperature of 303 K by the heat flux method, spanning CO2 fractions of 0.50-0.75, H2 fractions of 0.20-0.70, and equivalence ratios of 0.6-1.5. Evaluations of three kinetic models (modified
Study regionThe study encompasses Sweden (450 000 km2) located on the Scandinavian Peninsula in northern Europe.Study focusWe quantified the future crop-water demand and water-irrigation needs of 30,000 km² arable land across Sweden to prepare for climate adaptation. We applied a spatially distributed catchment-scale (40,000 sub-basins) hydrological model with an irrigation routine according to FA
