Haemoglobin adducts and specific immunoglobulin G in humans as biomarkers of exposure to hexahydrophthalic anhydride
The aim of this study was to determine whether haemoglobin adducts (Hb) of hexahydrophthalic anhydride (HHPA) and HHPA-specific immunoglobulin G (IgG) can be used as biomarkers of exposure to HHPA. The exposures of HHPA in 10 workers were determined from the mean urinary hexahydrophthalic acid (HHP acid) levels (range 76-3300 nmol HHP acid mmol-1 creatinine) during a period of 4 weeks. Blood was c
