PURPOSE OF REVIEW: Immune thrombocytopenia (ITP) is a bleeding disorder in which both antibody and cell-mediated autoimmune responses are directed against an individual's own platelets and/or megakaryocytes, leading to either enhanced platelet destruction and/or reduced platelet production, respectively. The cause of this platelet-specific autoimmunity remains unknown, but there has been a constan

Transfusion-related acute lung injury (TRALI) is a serious complication of transfusion and has been ranked as one of the leading causes of transfusion-related fatalities. Nonetheless, many details of the immunopathogenesis of TRALI, particularly with respect to recipient factors are unknown. We used a murine model of antibody-mediated TRALI in an attempt to understand the role that recipient lymph

An understanding of how helper T cells are activated to drive blood group immune responses will help to explain the immunogenicity of antigens such as HPA-1a. In this issue of Blood, Anani Sarab and colleagues identify the naturally processed HPA1a peptides recognized by T cells and set the stage for peptide-based therapies in NAIT.(1).

Lymphodepletion strategies are used in the setting of transplantation (including bone marrow, hematopoietic cell, and solid organ) to create space or to prevent allograft rejection and graft versus host disease. Following lymphodepletion, there is an excess of IL-7 available, and T cells that escape depletion respond to this cytokine undergoing accelerated proliferation. Moreover, this environment

INTRODUCTION: Beta-cell replacement by human islets or whole pancreas offers a life-saving therapeutic remedy for patients suffering from type 1 diabetes, providing considerable advantages with respect to diminishing total daily insulin dose and lowering frequencies of debilitating hypoglycemic reactions as well as preventing chronic micro- and macrovascular complications. Although remarkable prog

This article describes an innovative transnational education project involving three European universities, funded through ERASMUS+. One of its aims was to develop and provide a curriculum to facilitate students’ understanding and identification of occupational (in)justice by exposing them to marginalised people living in three European communities with differing cultural, social, and political sy

Irans nye president har starka kopplingar till landets högste ledare Ali Khamenei, och Iran kommer att fortsätta på den inslagna vägen av diktatur och förtryck, hävdar debattörerna Arvin och Ardavan Khoshnood i en analys av den nye presidenten och Irans framtid under honom.Iran’s new president has strong ties to the country’s supreme leader Ali Khamenei, and Iran will continue on the path of dictatorship and oppression, argue debaters Arvin and Ardavan Khoshnood in an analysis of the new president and Iran’s future under him.

Objective: The objective is to analyze Danish consumers' attitudes to buying food with reduced salt content. Design: The study is based on a comprehensive store intervention that included 114 stores belonging to the same supermarket chain. Three different salt claims were tested for eight weeks on six test products within the categories bread, cornflakes and frozen pizzas. Scanner data were supple

Blog entry based on QAnon and 9/11 truthers on how the anthropological understanding of religious belief can be applied to conspiracy believers.

Chapter in a Festschrift to anthropologist Chris Hann. Focuses on his work in Eastern Europe and Eurasia, especially the notions of how people 'accommodate' the regimes, concepts of civil society, resilience and surveillance as a unifying concept for Hann's work on Eurasia.

Danish media have published sympathetic portraits of asylum seekers seeking special dispensation from the Danish immigration laws, typically the brilliant Syrian gymnasium student facing deportation because theri temporary permiet has expired. The immigration minister has said that 'No one will get asylum just because you have been on TV'. This article proposes a set of satirical dispensation parg

Using examples from fieldwork among armed groups in Congo and pre-1989 Romania, this article argues against the prevailing ethos of ethnographers engagement with the people they study, in favor of a dynamic between engagement and detachment, what we call 'emotional management'. Two examples from our fieldwork are given, Hedlund on fieldwork with armed groups, Sampson on his informants being haraas

This paper describes some common features of so-called 'Critical' study areas such as Critical Trafficking Studies or Critical Development Studies, and then, based on analysis of the anti-corruption industry, tries to establish what a Critical Corruption Studies would be like compared to conventional studies.

Both inflammatory proteins and microRNAs (miRNA) have been reported to be associated with various psychiatric disorders. However, the association between inflammatory proteins and miRNAs remains largely unknown, especially for patients with depression, anxiety, or stress- and adjustment disorders. In this study, we analyzed plasma levels of 92 inflammatory proteins from 178 patients with depressio