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International differences in the selection and outcome of minimally invasive and open distal pancreatectomy : A transatlantic analysis

BACKGROUND: The efficacy and safety of minimally invasive distal pancreatectomy have been confirmed by randomized trials, but current patient selection and outcome of minimally invasive distal pancreatectomy in large international cohorts is unknown. This study aimed to compare the use and outcome of minimally invasive distal pancreatectomy in North America, the Netherlands, Germany, and Sweden.ME

Surveillance after surgery for pancreatic cancer : a global scoping review of guidelines and a nordic Survey of contemporary practice

OBJECTIVES: Most patients with pancreatic cancer who have undergone surgical resection eventually develop disease recurrence. ‍This study aimed to investigate whether there is evidence to support routine surveillance after pancreatic cancer surgery, with a secondary aim of analyzing the implementation of surveillance strategies in the Nordic countries.MATERIALS AND METHODS: A scoping review was co

Pancreatic surgery outcomes : multicentre prospective snapshot study in 67 countries

BACKGROUND: Pancreatic surgery remains associated with high morbidity rates. Although postoperative mortality appears to have improved with specialization, the outcomes reported in the literature reflect the activity of highly specialized centres. The aim of this study was to evaluate the outcomes following pancreatic surgery worldwide.METHODS: This was an international, prospective, multicentre,

Minimally invasive robot-assisted and laparoscopic distal pancreatectomy in a pan-European registry a retrospective cohort study

BACKGROUND: International guidelines recommend monitoring the use and outcome of minimally invasive pancreatic surgery (MIPS). However, data from prospective international audits on minimally invasive distal pancreatectomy (MIDP) are lacking. This study examined the use and outcome of robot-assisted (RDP) and laparoscopic (LDP) distal pancreatectomy in the E-MIPS registry.PATIENTS AND METHODS: Pos

Tailoring the Use of Central Pancreatectomy Through Prediction Models for Major Morbidity and Postoperative Diabetes : International Retrospective Multicenter Study

OBJECTIVE: To develop a prediction model for major morbidity and endocrine dysfunction after CP which could help in tailoring the use of this procedure.SUMMARY BACKGROUND DATA: Central pancreatectomy (CP) is a parenchyma-sparing alternative to distal pancreatectomy for symptomatic benign and pre-malignant tumors in body and neck of the pancreas CP lowers the risk of new-onset diabetes and exocrine

Use and outcome of minimally invasive pancreatic surgery in the European E-MIPS registry

BACKGROUND: The European registry for minimally invasive pancreatic surgery (E-MIPS) collects data on laparoscopic and robotic MIPS in low- and high-volume centers across Europe.METHODS: Analysis of the first year (2019) of the E-MIPS registry, including minimally invasive distal pancreatectomy (MIDP) and minimally invasive pancreatoduodenectomy (MIPD). Primary outcome was 90-day mortality.RESULTS

Nationwide prospective audit of pancreatic surgery : design, accuracy, and outcomes of the Dutch Pancreatic Cancer Audit

BACKGROUND: Auditing is an important tool to identify practice variation and 'best practices'. The Dutch Pancreatic Cancer Audit is mandatory in all 18 Dutch centers for pancreatic surgery.METHODS: Performance indicators and case-mix factors were identified by a PubMed search for randomized controlled trials (RCT's) and large series in pancreatic surgery. In addition, data dictionaries of two nati

Early onset pancreatic cancer : a controlled trial

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) represents the fourth cause of death in cancer with a 5-year survival rate of less than 1-2%. Early onset pancreatic cancer (EOPC), i.e. patients below 50 years of age, is infrequently described. The present study aimed to determine the epidemiology, demographic incidence and prognosis of EOPC and to identify the characteristics that might distin

Freshwater exploitation at Ajvide : Pitted ware culture fishing practises investigated through laser ablation facilitated strontium isotope analyses

The importance of marine resources for the Neolithic hunter-fisher-gathers of the Pitted Ware Culture of Gotland, Sweden, is well documented through zooarchaeological analyses and diet studies of human remains. Terrestrial areas were important for living and supplementing the diet but the extent of the terrestrial territories and regions of land use for different groups is largely unknown. The pre

Assessing Digital Breast Tomosynthesis Impact on Early Cancer Detection : Insights from Consecutive Screening

Background: Analysis of how digital breast tomosynthesis (DBT) screening affects consecutive screening performance is important to estimate its future value in screening. Purpose: To evaluate whether DBT contributes to early detection of breast cancer by assessing cancer detection rates (CDRs), including the fraction of invasive cancers and cancer subtypes in consecutive routine digital mammograph

The active, the sympathetic, and the reluctant: political action and eco-social attitudes among Swedish residents

In this study, we investigate how eco-social attitudes are interlinked with various modes of political action aimed at preventing environmental change and promoting social welfare. Using multiple correspondence analysis and cluster analysis, we explore the links between attitudes and political action, and associated socio-political characteristics, in the case of Sweden. Our results show a three-nIn this study, we investigate how eco-social attitudes are interlinked with various modes of political action aimed at preventing environmental change and promoting social welfare. Using multiple correspondence analysis and cluster analysis, we explore the links between attitudes and political action, and associated socio-political characteristics, in the case of Sweden. Our results show a three-n

Exploratory rasch analysis of a static-99R clinical cohort assessment

Modern test theory supplements the more prevalent classic methods for assessing test properties. However, such an assessment of the commonly used sexual recidivism risk assessment instrument, Static-99R, has yet to be attempted. This study evaluated the psychometric properties of said instrument using Rasch analysis. The clinical cohort assessed consisted of individuals with mental disorders convi

Effects of Recombinant α1-Microglobulin on Early Proteomic Response in Risk Organs after Exposure to 177Lu-Octreotate

Recombinant α1-microglobulin (A1M) is proposed as a protector during 177Lu-octreotate treatment of neuroendocrine tumors, which is currently limited by bone marrow and renal toxicity. Co-administration of 177Lu-octreotate and A1M could result in a more effective treatment by protecting healthy tissue, but the radioprotective action of A1M is not fully understood. The aim of this study was to exami

How the presence of a giant planet affects the outcome of terrestrial planet formation simulations

The architecture and masses of planetary systems in the habitable zone could be strongly influenced by the presence of outer giant planets. Here, we investigate the impact of outer giants on terrestrial planet formation, under the assumption that the final assembly of the planetary system is set by a giant impact phase. Utilizing a state-of-the-art N-body simulation software, GENGA, we interpret h

Substantial and Rapid Increase in Soil Health across Crops with Conversion from Conventional to Regenerative Practices

Interest in soil health is growing, though the speed and effectiveness of management practices in improving it are uncertain. We measured biological, chemical, and physical indicators of soil health within a working farm zero, five, and nine years after transitioning from regular applications of inorganic fertilizers and pesticides to cover cropping, compost additions, organic amendments, and rota

Proton Beam APerture MoniTor instrument design and overview for the Commissioning and Operation of ESS High Power Beam on Target

This paper presents a detector developed to protect the ESS spallation target. The detector is installed to receive a proton beam that has a peak current of 62.5 mA, an average power of 5 MW, and energy up to 2 GeV. It is designed to detect any part of the proton beam that goes outside a defined aperture, which is deemed as an errant beam condition. This detector is mainly used for machine protect

Prevalence and Trends of Not Receiving a Dose of DPT-Containing Vaccine Among Children 12-35 Months : An Analysis of 81 Low- And Middle-Income Countries

Not receiving a DPT-containing vaccine in early childhood indicates an absence of routine immunization, which puts children at an elevated risk of mortality, morbidity, and worse human development over the life course. We estimated the percentage of children 12-35 months who did not receive a dose of DPT-containing vaccine (termed zero-dose children) using household surveys from 81 low- and middle

Association between neonatal mortality and births not weighed among 400 thousand institutional deliveries in 32 low- and middle-income countries

BACKGROUND: Low birthweight (LBW) children have a higher risk of neonatal mortality. All institutional deliveries, therefore, should be weighed to determine appropriate care. Mortality risk for newborns who are not weighed at birth (NWB) is unknown.METHODS: This paper used logit regression models to compare the odds of death for NWB neonates to that of other neonates using data on 401 712 institut

Electronic Properties of Group-III Nitride Semiconductors and Device Structures Probed by THz Optical Hall Effect

Group-III nitrides have transformed solid-state lighting and are strategically positioned to revolutionize high-power and high-frequency electronics. To drive this development forward, a deep understanding of fundamental material properties, such as charge carrier behavior, is essential and can also unveil new and unforeseen applications. This underscores the necessity for novel characterization t