The tumor microenvironment (TME) is composed of various cellular components such as tumor cells, stromal cells including fibroblasts, adipocytes, mast cells, lymphatic vascular cells and infiltrating immune cells, macrophages, dendritic cells and lymphocytes. The intricate interplay between these cells influences tumor growth, metastasis and therapy failure. Significant advancements in breast canc

The importance of reducing environmental impacts has gained speed in the contemporary global context. Stabilization/Solidification (S/S) has become a practical method for handling polluted dredged sediments to make them usable as a construction material. This study aims to evaluate the environmental and economic impacts of a 48,586 m2 port, with stabilized dredged sediment, by focusing on the prod

Objective To review the efficacy of exercise interventions on sport-related concussion (SRC) incidence, as well as on linear and rotational head accelerations, and isometric neck strength and to assess reporting completeness of exercise interventions using the Consensus on Exercise Reporting Template (CERT).Design Systematic review and meta-analysis, according to the Prisma in Exercise, Rehabilita

Ett av mina första uppdrag som nybliven professor i Medicinsk Strålningsfysik vid Lunds Universitet var att i slutet av april 1981 åka till München för att delta i en Europeisk (EU) workshop om möjligheterna att reducera patient bestrålning vid röntgendiagnostik. Av deltagarna från Storbritannien framkom att man på flera håll i Storbritannien utvecklade metoder för medicinsk avbildning utan röntge

Skolan ska vara en plats för kreativ fostran, där unga människor växer till kloka,kunniga och fritt tänkande individer som lär sig att leva i ett samhälle. Därmed blirskolan något av det viktigaste vi har. Om skolan brister riskerar detta att få allvarligakonsekvenser för både individ och samhälle.Likväl finns det mycket som tyder på att svensk skola har allvarliga brister.Resultaten i internation

One of the most challenging aspects of X-ray research is the delivery of liquid sample flows into the soft X-ray beam. Currently, cylindrical microjets are the most commonly used sample injection systems for soft X-ray liquid spectroscopy. However, they suffer from several drawbacks, such as complicated geometry due to their curved surface. In this study, we propose a novel 3D-printed nozzle desig

In this work, regenerated cellulose textile fibers, Ioncell-F, dry-wet spun with different draw ratios, have been investigated by scanning wide-Angle X-ray scattering (WAXS) using a mesoscopic X-ray beam. The fibers were found to be homogeneous on the 500nm length scale. Analysis of the azimuthal angular dependence of a crystalline Bragg spot intensity revealed a radial dependence of the degree of

For a century, transport systems have been governed by masculine norms, constraining both women and men within the conditions and mobility behaviour it has established. This article explores the potential implications of adopting feminine norms for mobility and transport systems. Current masculine mobility norms are contested by investigating what including a feminine mobility concept would entail

Context. The search for small exoplanets around solar-type stars is limited by stellar physical variability, such as a jittering in the apparent photospheric radial velocity. While chromospheric variability has been aptly studied, challenges remain for the observation, modeling. and understanding the much smaller fluctuations in photospheric spectral line strengths, shapes, and shifts. Aims. Extre

Anxiety before an MRI examination is common, even though the technique is noninvasive and painless. In a 7T MRI study, healthy volunteers also reported anxiety before the examination. This study aimed to assess anxiety levels in healthy individuals undergoing 7T MRI and to determine if their anxiety decreased during subsequent examinations. Participants filled out a questionnaire on anxiety. Eleve

BACKGROUND: Minimally invasive pancreatoduodenectomy (MIPD) has emerged as an alternative to open pancreatoduodenectomy (OPD). However, the extent of variation in the use and outcomes of MIPD in relation to OPD among countries is unclear as international studies using registry data are lacking. This study aimed to investigate the use, patient selection, and outcomes of MIPD and OPD in four transat

The evolution of human adaptations across diverse geographical regions has been shaped by dynamic interplays between environmental demands and cultural evolution throughout millennia. During the Pleistocene epoch, cultural variations were relatively uniform globally, harmonizing with the Ice Age climate that created vast analogous environments. At the end of the Late Pleistocene—the start of the H

BACKGROUND: Pancreatic adenocarcinoma located in the pancreatic body might require a portomesenteric venous resection (PVR), but data regarding surgical risks after distal pancreatectomy (DP) with PVR are sparse. Insight into additional surgical risks of DP-PVR could support preoperative counseling and intraoperative decision making. This study aimed to provide insight into the surgical outcome of