Sökresultat

This study investigates the efficacy of tumor radioimmunotargeting with 125I-labeled BR96-biotin monoclonal antibody using a new method, whole-blood immunoadsorption (WBIA), based on direct adsorption of unbound monoclonal antibody (MAb) from blood without preceding separation of plasma. METHODS: Highly tumor-reactive, internalizing, chimeric BR96 MAb of isotype IgG1 binds to a tumor-associated Le

Objective - To investigate the feasibility of monophasic action potential ( MAP) mapping using an electro-anatomical mapping system ( CARTO) in obtaining information on global dispersion of atrial repolarization and to evaluate the role of dispersion of repolarization in the genesis of paroxysmal atrial fibrillation ( PAF). Methods and results - Right atrial MAPs were recorded from 53 +/- 18 sites

alpha(1)-Microglobulin, also called protein HC, is a lipocalin with immunosuppressive properties. The protein has been found in a number of vertebrate species including frogs and fish. This review summarizes the present knowledge of its structure, biosynthesis, tissue distribution and immunoregulatory properties. alpha(1)-Microglobulin has a yellow-brown color and is size and charge heterogeneous.

Lentiviral vectors are promising tools for the development of gene therapy since they can transduce both quiescent and dividing target cells. Lentiviral vectors may be particularly promising gene delivery tools for hematopoietic stem cells since these target cells tend to be quiescent and are therefore difficult target cells for vectors that require dividing targets. Human hematopoietic stem cells

Investigations of nitrogen retention in artificially flooded wetlands were performed in southern Sweden during 1991-1993. The purpose of the study was to investigate whether artificial flooding of meadows would be a possible means of reducing the nitrogen content in streams and rivers. Two case studies are presented, one from a sandy/organic soil, one from a peaty soil. Overall nitrogen retention

Objectives: To compare men with prostate disease with those from the general population regarding polymorphisms in the androgen receptor gene and in the 5 alpha-reductase II (SRD5A2) gene. Materials and methods: The SRD5A2 polymorphisms A49T, V89L and R227Q, the androgen receptor CAG and GGN repeats and sex hormone status was investigated in men with prostate cancer (CaP) (n = 89), benign prostate

Phosphorus-31 NMR spectra of superfused isometrically mounted guinea-pig taenia coli were obtained using a horizontal probe at 103.2 MHz. The spectra showed resonances for ATP, phosphocreatine (PCr), and a sugar phosphate resonance. The PCr/ATP ratio was between 1.5 and 2.0 consistent with chemical analysis of tissue extracts. The level of PCr, but not of ATP, decreases reversibly during contracti

Photoelectron and Auger electron spectra following Xe-3d and Xe-4d ionization of free xenon clusters have been measured using synchrotron radiation. The atom-to-surface and atom-to-bulk binding energy shifts found in the Xe-3d and the subsequent M5N4,5N4,5 Auger decay are about 15% larger than those observed in the Xe-4d and N4,5O2,3O2,3 measurements. This experimental result is also considered th

A preliminary systematic position of the genus Cetrariella based on sequences from the ITS region is discussed. Cetrariella delisei and C. fastigiata appear as not very closely related species. Both species form a monophyletic sister group to Cetraria and should presumably stay as a separate segregate. The evidences from morphological data and data from secondary chemistry, however, strongly suppo

As carotid endarterectomy is a prophylactic procedure, it would seem particularly important to analyze complications with an aim to avoiding them. All carotid endarterectomies in Sweden are registered, and all serious complications (death and permanent neurological deficit) are analyzed in detail, classified and discussed within the profession. During the period 1994-1996 the frequency was 4.3 per

We present and discuss the Cs 3d X-ray absorption spectra and resonant photoelectron emission spectra of CsF. The resonant photoelectron spectra excited at the Cs 3d absorption maxima, exhibit a strong resonance behavior. The different behaviour of participator and spectator channels and interference effects of the 4d partial photoionisation cross-section at the 3d resonances are discussed. The ex

AIM: To study the vasodilation effect of atropine and its mechanism. METHODS: Isometric tension was recorded in isolated rat super mesenteric arteries precontracted by noradrenaline (NE) to study the vasodilation effect of atropine, and to investigate the role of endothelial cell and vascular smooth muscle cell on vasodilation. RESULTS: Atropine was shown to significantly dilate the endothelium-in

OBJECTIVE: To determine whether serum cystatin C is more accurate than serum creatinine in the detection of diabetic nephropathy, also after adjustment for age.METHODS: Forty-one patients with type 1 and 82 patients with type 2 diabetes were evaluated with serum creatinine, serum cystatin C, and (51)Cr-EDTA clearance (reference method). Cystatin C was measured by a particle-enhanced turbidimetric

The adaptive optics for any telescope in the 25- to 100-m class will be complex. It is believed that adaptive optics should, to the maximum extent, be designed as an integrated part of a telescope. The proposed Swedish 50-m Extremely Large Telescope is considered here to illustrate the principle of integrated adaptive optics. Two alternative designs both using the Ritchey-Chretien telescope system

The transition model (i) of classical phonetics distinguished between inevitable transitions between momentary target configurations (called coarticulation by Menzerath and Lacerda in 1933) and assimilation extending over a larger domain than a transition, implying reorganization of the input. By the 1950s it was clear that coarticulation extended beyond target configurations and involved more tha

Two important contexts for children in forensic processes are their performance in interviews and their identification performance in lineups. Another important question concerns the validity (or realism) in children’s confidence in the extent to which they correctly remember an event or a person. This paper reviews the current state of research on strengths and weaknesses in children’s testimony