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Resource utilization in mental illness–evaluation of an instrument for measuring direct costs of treatment for patients with severe mental illness (SMI)

Purpose: Serious mental illnesses (SMIs) exert a considerable financial burden on health-care systems. In this study, the resource utilization in mental illness (RUMI) tool was developed and employed to evaluate resource utilization in patients with SMI. Materials and methods: Data from 107 patients with SMI treated in four psychiatric outpatient clinics in Sweden were collected. The relationships

Clonal Hematopoiesis Is Associated with Higher Risk of Stroke

Background and Purpose: Clonal hematopoiesis of indeterminate potential (CHIP) is a novel age-related risk factor for cardiovascular disease-related morbidity and mortality. The association of CHIP with risk of incident ischemic stroke was reported previously in an exploratory analysis including a small number of incident stroke cases without replication and lack of stroke subphenotyping. The purp

Predictors of hypogammaglobulinemia in ANCA-associated vasculitis after a rituximab-based induction : a multicentre study

OBJECTIVES: Rituximab has become the cornerstone of induction treatment in ANCA-associated vasculitis (AAV). B cell depletion may increase the risk of hypogammaglobulinemia, potentially leading to severe infections. This study aims to assess factors associated with hypogammaglobulinemia in AAV patients treated with rituximab.METHODS: This retrospective cohort study included AAV patients treated wi

Patients having surgery for ulnar nerve compression at the elbow rarely have affection of the spinal nerve root at C8-Th1 levels

Cervical pathology may contribute to residual problems after surgery for ulnar nerve compression. We aimed to evaluate the presence of pathological conditions in spinal cord and cervical spinal nerve roots in patients surgically treated for ulnar nerve compression at elbow. In a cohort of patients, surgically treated for ulnar nerve compression at elbow, magnetic resonance images (MRI; performed 3

CHEOPS geometric albedo of the hot Jupiter HD 209458 b

We report the detection of the secondary eclipse of the hot Jupiter HD 209458 b in optical/visible light using the CHEOPS space telescope. Our measurement of 20.4−3.3+3.2 parts per million translates into a geometric albedo of Ag = 0.096 ± 0.016. The previously estimated dayside temperature of about 1500 K implies that our geometric albedo measurement consists predominantly of reflected starlight

Indeterminacy and Underdetermination

A collection of cutting edge research on indeterminacy and underdetermination. Includes contributions from Ethics, Metaethics, Epistemology, Philosophy of Science, Metaphysics, Philosophy of Language, Logic Philosophy of Computation.

A Qualitative Systematic Review About Children’s Everyday Lives when a Parent Is Seriously Ill with the Prospect of Imminent Death - Perspectives of Children and Parents

Parental dying is a life changing experience for children. This study explores children’s strategies and (inter)actions in their everyday life when facing critically ill parents and imminent death, from the children’s and parents’ perspectives. A qualitative systematic review was carried out, registered in PROSPERO (CRD42022306862). A literature search and screening in six databases resulted in ei

Leonardo da Vinci

Leonardo da Vinci var en gudabenådad konstnär, en vetenskapsman som levde hundratals år före sin tid och ett universalgeni som fick övriga renässansmänniskor att förblekna. Han tillhör det ringa fåtal individer som alltid har varit föremål för allmän beundran. Samtliga bedömare, från läraren Verrocchio och renässanshärskarna i Milano och Frankrike till nutidens kritiska granskare, har varit rörand