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Purpose: We present a case report that describes neoadjuvant denosumab therapy initiated in a child with a solitary giant cell-rich juvenile xanthogranuloma tumor involving the spine, and review the current literature.Methods: A giant cell-rich histiocytic lesion involving the 11th thoracic vertebral body was identified in a healthy 5-year-old girl with persistent back and pelvic pain for several

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The decomposition of large stocks of soil organic carbon in thawing permafrost might depend on more than climate change-induced temperature increases: indirect effects of thawing via altered bacterial community structure (BCS) or rooting patterns are largely unexplored. We used a 10-year in situ permafrost thaw experiment and aerobic incubations to investigate alterations in BCS and potential resp

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Ganga River system is a life support system to sustain the people of northeast region, India, by providing freshwater resource. In this study, the seasonal heavy metal concentrations of Ganga River system at Haridwar region (India) have been characterised for metal pollution. The collection of water samples was done from 10 different locations and analysed for various metal parameters (Zn, Pb, Mn,

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Background and purpose — The optimal treatment for traumatic cartilage injuries remains unknown. Contrast-enhanced MRI of cartilage (dGEMRIC) evaluates cartilage quality and a low dGEMRIC index may predict radiographic osteoarthritis (OA). The purpose of this study was (a) to explore the results 17 years after surgical treatment of an isolated cartilage knee injury and (b) to evaluate the predicti

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Alloimmunization against the RhD antigen is the most common cause of hemolytic disease of the fetus and newborn. Antenatal anti-D prophylaxis in addition to postnatal anti-D prophylaxis reduces the number of RhD-immunizations compared to only postnatal administration. Cell-free fetal DNA released from the apoptotic trophoblastic placental cells into the maternal circulation can be used to determin

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Background: A common complaint by people with tinnitus is that they experience that the tinnitus causes attention and concentration problems. Previous studies have examined how tinnitus influences cognitive performance on short and intensive cognitive tasks but without proper control of hearing status. Purpose: To examine the impact tinnitus and high-frequency hearing thresholds have on reading co

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A three-session therapist-guided exposure treatment was tested in a consecutive series of eight primary health care patients suffering from panic attacks who specifically used distraction techniques as their primary safety behavior. The Panic Disorder Severity Scale Self-Report (PDSS-SR) was administered at baseline (1-3 weeks before the first session), and 1, 2, and 3 weeks after treatment. Weekl

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Background: Despite the presence of efferent neural pathways from the cortex to brainstem, evidence for cognitive inhibition and sensory gating on the auditory brainstem has been mixed. Some previous studies have suggested auditory brainstem responses (ABR) can be affected by cognitive load whereas others have not. Purpose: The present study explores if the ABR recorded from adults with normal hea

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Aims Dual coil (DC) electrodes are preferred to single coil (SC) electrodes because of an assumed higher shock efficacy. However, DC-electrodes may be associated with an increased difficulty and risk of lead extraction. We aimed to compare SC- and DC-electrodes with respect to the first shock efficacy (FSE) after implantable cardioverter defibrillator (ICD) implantation. Methods and results One th

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Deep learning has the potential to drastically increase the accuracy and efficiency of prostate cancer diagnosis, which would be of uttermost use. Today the diagnosis is determined manually from H&E stained specimens using a light microscope. In this paper several different approaches based on convolutional neural networks for prostate cancer classification are presented and compared, using th

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The Multi-Blade is a Boron-10-based gaseous thermal neutron detector developed to face the challenge arising in neutron reflectometry at neutron sources. Neutron reflectometers are challenging instruments in terms of instantaneous counting rate and spatial resolution. This detector has been designed according to the requirements given by the reflectometers at the European Spallation Source (ESS) i

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A direct search for the standard model Higgs boson decaying to a pair of charm quarks is presented. Associated production of the Higgs and Z bosons, in the decay mode ZH→ + -cc is studied. A data set with an integrated luminosity of 36.1 fb-1 of pp collisions at s=13TeV recorded by the ATLAS experiment at the LHC is used. The H→cc signature is identified using charm-tagging algorithms. The observe

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Hur kyrkan framträder i det lokala sammanhanget beror på vilka delar av omvärlden den kyrkliga aktören relaterar till. I artikeln presenteras en modell för att beskriva och analysera kyrkan som välfärdsaktör. Artikeln är framskriven i ett teologiskt aktionsforskningsprojekt med Mölndals pastorat, i ett samarbete mellan Svenska kyrkans forskningsenhet och Socialhögskolan i Lund.

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Kapitlet undersöker med hjälp av material från intervjuer och frågelistor vilka sociala relationer, normer och värderingar som sätts på prov vid lån och utlån av saker. Vilka förutsättningar finns det att genom erfarenheter från det privata lånandet öka lusten att delta i en mer hållbar delningsekonomi?