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Computational patient models for simulation of dynamic gamma-camera imaging : Application to renography and peptide receptor radionuclide therapy

Inom nuklearmedicinen utnyttjas radioaktiva läkemedel och strålningen som sänds ut från dessa för att diagnosticera och behandla ett flertal olika sjukdomar. Det radioaktiva läkemedlet ges ofta till patienten som en intravenös injektion, och läkemedlets egenskaper i kombination med patientens fysiologi och eventuella sjukdom avgör hur läkemedlet sedan fördelas, omsätts och utsöndras från kroppen. Many nuclear medicine investigations rely on gamma-camera imaging to study and quantify the distribution of radiopharmaceuticals or radionuclides in the patient as a function of time. This is typically used for diagnostic studies of physiological functions or for calculation of absorbed doses following radionuclide therapy. In this work, computational patient models (phantoms) have been developed

Identification and Quantification of Chemical Forms of Cu and Zn in MSWI Ashes Using XANES

Incineration is in many countries a common treatment method for municipal solid waste, and utilization of the ash residues has attracted significant interest. The bottom ash is best suited as a secondary construction material, whereas the fly ash is being investigated as a secondary raw material for recovery of, for example, Zn, Cu, and salts. For both types of application, knowledge about the che

Making Lab Sessions Mandatory-On Student Work Distribution in a Gamified Project Course on Market-Driven Software Engineering

Unfair work distribution in student teams is a common issue in project-based learning. One contributing factor is that students are differently skilled developers. In a course with group work intertwining engineering and business aspects, we designed an intervention to help novice programmers, i.e., we introduced mandatory programming lab sessions. However, the intervention did not affect the work

Does neighborhood alcohol availability moderate the impact of familial liability and marital status on risk for alcohol use disorders? A Swedish national study

Objective: The purpose of this study was to determine whether ease of access to alcohol at the neighborhood level moderates the impact of familial liability and marital status on risk for alcohol use disorder (AUD). Method: Individuals in Sweden were divided into those residing in a neighborhood with (n = 14.1%) versus without (n = 85.9%) an alcohol outlet (bars/nightclubs or government stores). A

Extending imaging range in magnetomotive ultrasound with tailored magnetic nanoparticles

In magnetomotive ultrasound (MMUS), magnetic nanoparticles (MNPs) are used as a contrast agent. A time-varying magnetic field displaces the MNPs which in turn move their closest surrounding - a motion detected with ultrasound. A limiting factor for MMUS is the magnetic force magnitude decay with depth, which restricts the imaging area. Several attempts to extend the imaging depth have been suggest

The magnetic force generation in magnetomotive ultrasound imaging

In magnetomotive ultrasound imaging, the tissue displacement due to a magnetic force on embedded magnetic nanoparticles is measured. It was previously shown that the nanoparticle contrast agent exhibits a non-linear magnetization characteristic, which is also reflected in the magnetomotive force. However, this non-linearity was rarely taken into account for the application. Here, the implications

Synthesis and Characterization of a Biocomposite Bone Bandage for Controlled Delivery of Bone-Active Drugs in Fracture Nonunions

Fracture nonunions are common in orthopedics and their treatment often involves multiple surgical interventions. The aim of this study was to fabricate and characterize a gelatin-nano-hydroxyapatite membrane (GM)-based bone bandage for controlled delivery of bio-active molecules; recombinant human bone morphogenic protein-2 (rhBMP-2) and zoledronic acid (ZA) to promote osteoinduction and prevent c

Evaluation and optimization of ICOS atmosphere station data as part of the labeling process

The Integrated Carbon Observation System (ICOS) is a pan-European research infrastructure which provides harmonized and high-precision scientific data on the carbon cycle and the greenhouse gas budget. All stations have to undergo a rigorous assessment before being labeled, i.e., receiving approval to join the network. In this paper, we present the labeling process for the ICOS atmosphere network

Associations of carbohydrates and carbohydrate-rich foods with incidence of type 2 diabetes

Dietary carbohydrates have long been expected to be associated with risk of type 2 diabetes; however, the associations for many carbohydrates and carbohydrate-rich foods remain inconclusive. This study analysed associations between intakes of six types of carbohydrates and thirteen carbohydrate-rich foods with incident type 2 diabetes in 26 622 participants (61% women) in the Malmö Diet and Cancer

Changing the System Culture : Mobilizing the Social Sciences in the Swedish Nuclear Waste System

The purpose of this paper is to analyze how competence in the humanities and social sciences has been introduced into the system culture of the Swedish nuclear waste system (SNWS) traditionally dominated by scientists and engineers. In the spring of 1980, fierce local protests were directed against drilling teams sent out to investigate the geology of potential locations for a repository of spent

Long-term outcome of the Surgisis® (Biodesign®) anal fistula plug for complex cryptoglandular and Crohn’s fistulas

Aim: To evaluate the long-term success rate of treatment with the Surgisis® (Biodesign®) anal fistula plug for complex anal fistulas, assess fistula plug failure over time and compare success rates for fistula plug between a group of patients with cryptoglandular fistula and another group with Crohn's fistula. Method: This is a single-centre study of consecutive patients treated with the Surgisis®

Predictability of food supply modulates nocturnal hypothermia in a small passerine : Food supply and nocturnal hypothermia

The combination of short days and long cold winter nights, in temperate regions, presents a major challenge for small diurnal birds. Small birds regularly employ heterothermy and enter rest-phase hypothermia during winter nights to conserve energy. However, we know little about how environmental conditions, such as food availability, shape these strategies. We experimentally manipulated food avail

Combining expansion in pulp capacity with production of sustainable biofuels – Techno-economic and greenhouse gas emissions assessment of drop-in fuels from black liquor part-streams

Drop-in biofuels from forest by-products such as black liquor can help deliver deep reductions in transport greenhouse gas emissions by replacing fossil fuels in our vehicle fleet. Black liquor is produced at pulp mills that can increase their pulping capacity by upgrading some of it to drop-in biofuels but this is not well-studied. We evaluate the techno-economic and greenhouse gas performance of

Transcultural Music-Making in Contemporary Music Ensembles : Five Approaches in Germany, the Netherlands, Uzbekistan and Turkey

The present article describes the approaches of five ensembles specialized in transcultural music-making in the context of contemporary music in Germany, the Netherlands, Uzbekistan and Turkey. While facing similar underlying conceptual and practical challenges in the process of combining different musical traditions and cultural backgrounds, such as the question of how to merge oral and notated t