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AimTo investigate whether intensive multifactorial treatment can reverse the predisposed adverse phenotype of people with Type 2 diabetes who have a family history of diabetes. MethodsData from the randomized controlled trial ADDITION-Denmark were used. A total of 1441 newly diagnosed patients with diabetes (598 with family history of diabetes) were randomized to intensive treatment or routine car

An introduction into the area of inverse problems for the Schrodinger operators on metric graphs is given. The case of metric finite trees is treated in detail with the focus on matching conditions. For graphs with loops we show that for almost all matching conditions the potential on the loop is not determined uniquely by the Titchmarsh-Weyl function. The class of all admissible potentials is cha

Background: A number of single nucleotide polymorphisms (SNPs) have been associated with broadband ultrasound attenuation (BUA) and speed of sound (SOS) as measured by quantitative ultrasound (QUS) at the calcaneus in the Framingham 100K genome-wide association study (GWAS) but have not been validated in independent studies. The aim of this analysis was to determine if these SNPs are associated wi

The effects of self-assembly on the hydrolysis kinetics of surfactants that contain ester bonds are discussed. A number of examples on how reaction rates and apparent reaction orders can be modulated by changes in the conditions, including an instance of apparent zero-order kinetics, are presented. Furthermore, it is shown that the examples on reaction kinetics display parallels and connections to

The jet energy scale (JES) and its systematic uncertainty are determined for jetsmeasured with the ATLAS detector using proton-proton collision data with a centre-of-mass energy of root s = 7 TeV corresponding to an integrated luminosity of 4.7 fb(-1). Jets are reconstructed from energy deposits forming topological clusters of calorimeter cells using the anti-kt algorithmwith distance parameters R

Context. Precise analyses of stellar radial velocities is able to reveal intrinsic causes of the wavelength shifts of spectral lines (other than Doppler shifts due to radial motion), such as gravitational redshifts and convective blueshifts. Aims. Gravitational redshifts in solar-type main-sequence stars are expected to be some 500 m s(-1) greater than those in giants. We search for this differenc

Biorefinery applications are receiving growing interest due to climatic and waste disposal issues and lack of petroleum resources. Jerusalem artichoke (Helianthus tuberosus L.) is suitable for biorefinery applications due to high biomass production and limited cultivation requirements. This paper focuses on the potential of Jerusalem artichoke as a biorefinery crop and the most viable products in

Boreal forest soils function as a terrestrial net sink in the global carbon cycle. The prevailing dogma has focused on aboveground plant litter as a principal source of soil organic matter. Using C-14 bomb-carbon modeling, we show that 50 to 70% of stored carbon in a chronosequence of boreal forested islands derives from roots and root-associated microorganisms. Fungal biomarkers indicate impaired

This study investigated a possible mechanism behind employment discrimination. Participants completed a recruitment task where emphasis on cohesion (employees should “fit in”) vs. fairness (everybody should be treated equally) was manipulated by describing the norms of a fictitious company differently. There was a comparatively stronger preference in the cohesion condition for traits and interview

In recent decades, many marine populations have experienced major declines in abundance, but we still know little about where management interventions may help protect the highest levels of marine biodiversity. We used modeled spatial distribution data for nearly 12,500 species to quantify global patterns of species richness and two measures of endemism. By combining these data with spatial inform

One of the major research areas in computer vision is scene reconstruction from image streams. The advent of RGB-D cameras, such as the Microsoft Kinect, has lead to new possibilities for performing accurate and dense 3D reconstruction. There are already well-working algorithms to acquire 3D models from depth sensors, both for large and small scale scenes. However, these methods often break down w

Using high-quality precipitation data from 524 stations, the trends of a set of precipitation variables during the main rain season (May-September) from 1961 to 2008 for different climate regions in China were analysed. However, different characteristics were displayed in different regions of China. In most temperate monsoon regions (north-eastern China), total rain-season precipitation and precip

Introduction: Bipolar disorder is characterized by severe mood symptoms including major depressive and manic episodes. During manic episodes, many patients show cognitive dysfunction. Dopamine and glutamate are important for cognitive processing, thus the COMT and DAOA genes that modulate the expression of these neurotransmitters are of interest for studies of cognitive function. Methodology: Focu

Popular Abstract in Swedish Humant immunbristvirus (HIV) orsakar förvärvat immunbristtillstånd (AIDS). HIV/AIDS-epidemin har hittills innefattat över 60 miljoner människor som har infekterats och över 30 miljoner av dessa har avlidit i AIDS. HIV-infektion smittar via blod, sexuellt och från mor till barn vid graviditet eller via bröstmjölk. Vid infektion infogas virusets arvsmassa i den infekteradHIV-1 is dominating the global HIV pandemic, while HIV-2 is mainly confined to West Africa. The highest HIV-2 prevalence figures have been reported from Guinea-Bissau. While HIV-1 infection almost invariably leads to progressive immune dysfunction and AIDS, HIV-2 infection is characterised by a smaller proportion of individuals with disease progression to AIDS. In order to monitor the long-term e