alpha-Trinositol inhibits FGF-stimulated growth of smooth muscle and breast cancer cells
alpha-Trinositol (D-myo-inositol-1,2,6-trisphosphate), an isomer of the intracellular messenger IP3, has been studied for its anti-inflammatory and other effects in animal experiments and in human. The mechanisms of action remain unknown. Several human pathologies are associated with uncontrolled production of fibroblast growth factors (FGFs). FGF-2 induces vascular smooth muscle cell proliferatio
