About 10% of the patients with neurofibromatosis type 1 (NF1) develop malignant peripheral nerve sheath tumors (MPNSTs), accounting for half of all MPNST cases. Several nonrandom chromosomal aberrations have been found, but the target genes remain mostly unrecognized. Mutations in the NF1 and TP53 genes have been found in some MPNSTs, and recent data from mouse models support a synergistic effect

Strain-induced tendinopathy is a common injury in both human and equine athletes, with increasing incidence associated with greater involvement in sport and an increasingly aged population. This paper reviews our studies on the abundant non-collagenous protein, cartilage oligomeric matrix protein (COMP), in equine tendons. Its variation between tendon type and site, age and exercise has provided a

A Gla domain-mutated protein C variant, QGNSEDY, modified at positions 10-12, 23, 32-33, and 44, having enhanced affinity for negatively charged phospholipid and increased anticoagulant potential, was used to elucidate the importance of the interaction between the Gla domain and the phospholipid for the ability of activated protein C (APC) to inactivate factor Va (FVa). FVa degradation by wild typ

The images of commercial potato chips were evaluated for various colour and textural features to characterize and classify the appearance and to model the quality preferences of a group of consumers. Features derived from the image texture contained better information than colour features to discriminate both the quality categories of chips and consumers' preferences. Entropy of a* and V and energ

Popular Abstract in Swedish Arbete är centralt i det moderna samhället. Samtidigt står många människor av olika anledningar utanför den ordinarie arbetsmarknaden. Att detta i särskild utsträckning gäller personer med funktionshinder har i många länder fått till följd att lagstiftning antagits för att på olika sätt öka arbetskraftsdeltagandet för denna grupp. De bestämmelser som reglerar arbete ochThis doctoral thesis examines labour market legislation on disability and work in Sweden, England and Germany. In order to provide increased access to the labour market for people with disabilities all three studies countries have undertaken more of less far-reaching legislative measures over a number of decades, both in line with, or as a result of, general labour and employment legislation, but

Two natural glycoproteins/glycoenzymes, invertase and glucoamylase, and two neoglycoconjugates, synthetized from Saccharomyces cerevisiae mannan, bovine serum albumin and penicillin G acylase were tested for interaction with lectin Concanavalin A (Con A). The interaction of natural and synthetic glycoproteins with Con A was studied using three different experimental methods: (i) quantitative preci

A numerical algorithm is presented for the problem of a crack along the interface of an elastic inclusion embedded in an elastic plane subjected to uniform stress at infinity. The algorithm is based on a Fredholm integral equation of the second kind and allows for fast and accurate solutions to geometries of great complexity. In an example crack opening displacement and stress intensity factors ar

The effect of detritus originating from different plant species on denitrifying capacity was investigated in a Swedish wastewater treatment wetland. Intact sediment cores containing sediment with a detritus layer were collected from wetland basins dominated by Typha latifolia, Phragmites australis, or Elodea canadensis in November 2000 and potential denitrification was measured using the acetylene

Summary Many competitive breath-hold divers use 'glossopharyngeal insufflation', also called 'lung packing', to overfill their lungs above normal total lung capacity. This increases intrathoracic pressure, decreases venous return, compromises cardiac pumping, and reduces arterial blood pressure, possibly resulting in a syncope breath-hold divers call 'packing blackout'. We report a case with a bre

b1 integrins are thought to play a central role in maintaining lymphocytes within mucosal epithelia via their interactions with extracellular matrix proteins and subepithelial cellular components within and underlying the basement membrane. In the current study type a (CD8abTCRab) and type b (CD8aaTCRcd and CD8aaTCRab) intraepithelial lymphocyte (IEL) subsets within the mouse small intestine were

A lab-scale continuous microalgal culture was grown on sterile-filtered wastewater in order to clarify the phosphorus removing mechanisms in a microalgal treatment step that treats residual phosphorus from a hydroponic wastewater treatment pilot plant. The phosphorus assimilation was dependent on algal biomass production, whereas the chemical precipitation was dependent on phosphorus load, i.e. an

The purpose of the present study was to investigate the amplifying function of the nucleus accumbens septi region (NAS) in 6-hydroxydopamine (6-OHDA)-induced rotational behaviour by implanting fetal dopamine (DA)-rich mesencephalic cell suspensions unilaterally in the NAS of rats previously subjected to combined mesostriatal (MS) and NAS 6-OHDA lesions. First, all the rats received a unilateral 6-

Recent research has improved the possibilities of assessing the influence of various factors on wound healing. Thus, PH. SANDBLOM (1944)(4), PH. SANDBLOM and A. MUREN (1953, 1954)(6,7) and B. ZEDERFELDT (1957)(8) and others have elucidated the effect of technical, local and physiological factors on the rate of healing of skin wounds. It has been shown (e.g. by B. ZEDERFELDT (1957)(8)) that various

This is a case report of a contact allergic reaction on the face due to a skin cleansing product containing the amphoteric surfactant sodium cocoamphoacetate, occurring in an atopic woman with multiple contact sensitivities. Because of its weak irritant properties, this surfactant is widely used in cosmetic products intended to be used for sensitive skin, including products for intimate, and baby

Neurobehavioral deficits in neuromotor function, verbal memory, executive function and attention found in patients with schizophrenia and their relatives have been suggested to be liability indicators or predictors of schizophrenia. It remains uncertain which of these neurobehavioral deficits are components of the illness itself or characteristics associated with genetic risk for it. The purpose o