Popular Abstract in Swedish Målsättningen med detta avhandlingsarbete har varit att undersöka cyklin D1 och HIF-1 i förhållande till ÖR i brösttumörer. Ytterligare en målsättning var att undersöka om cyklin D1 och HIF-1 kan påverka utfallet av tamoxifenbehandling i kliniska bröstcancerstudier. I delarbete 1 fann vi att i ÖR-positiva tumörer med områden där tumörcellerna faktiskt var ÖR-negativa, Estrogen receptor (ER) status can define breast cancer patients who would benefit from adjuvant tamoxifen therapy. However, resistance to tamoxifen is often observed and possible mechanisms may be loss or reduction of ER, dysfunctional ER- signaling and ligand independent activation of the receptor. Hypoxia and hypoxia inducible factor-1? (HIF-1) expression has been correlated to loss of ER in bre

This report presents theories and measurements of the mechanisms af heat transfer in fibrous materials (e.g. insulation of mineral wool type), and measurements of these mechanisms. The present work is part af a larger research program at the Division of Building Technology, Lund Institute of Technology, for investigating the behaviour of fibrous material as thermal insulation. A preliminary versio

We report on the applications of a single-longitudinal-mode (SLM) pulsed alexandrite laser system for diagnostics of parameters of flow/combustion interest. The laser system is characterized by its narrow linewidth, high peak power, and broad tunablity. The absolute frequency of the laser output was monitored by a wavelength diagnostic system, which included a high-resolution confocal etalon and a

Popular Abstract in Swedish Om modellbibliotek för termo-hydrauliska tillämpningar. Matematiska modeller och simulering är viktiga verktyg för att hantera tekniska system. Speciellt som trenden idag är att öka komplexiteten i system genom integrerad produktion och processoptimering. Att hantera dessa komplexa system kräver kunskaper inom många områden samtidigt. Modellbibliotek är ett bra sätt atMathematical modelling and simulation are important tools when dealing with engineering systems that today are becoming increasingly more complex. Tightly integrated production and process optimization are trends that give rise to heterogeneous systems, which are difficult to handle without expertise in several engineering disciplines. Model libraries provide an excellent way to package engineerin

OBJECTIVE: The aim of this study was to determine whether bone quality, as assessed by osteometry and histologic parameters, can be used to predict implant integration in conjunction with maxillary sinus reconstruction. STUDY DESIGN: Twelve patients with severely atrophied maxillary alveolar processes were treated through use of a two-stage surgical reconstructive strategy with implant placement 4

The β-delayed neutron branches from neutron-rich Be-isotopes have been measured with a setup sensitive down to thermal energies. For 14Be a new value of Pn = 101 ± 4% has been found for the total neutron-emission probability and an upper limit of 2.4% (95% confidence level) is imposed on the combination P2n + 3P3n of multi-neutron emission probabilities. Moreover, an improved value of Pn = 0.50 ±

A spin-echo MRI sequence has been employed to measure moisture profiles during the drying of industrial never-dried pulp samples and was able to detect moisture even at very low:moisture content (6%). For the first time, moisture profiles have been measured for pulp samples approximately 2.5 mm thick with a spatial resolution of 0.15 mm under quite severe drying temperatures (up to 87 degrees C).

Several lines of evidence suggest that wetlands may be a major source of methylmercury (MeHg) to receiving waters, perhaps explaining the strong correlation between concentrations of waterborne MeHg and dissolved organic carbon (DOC) in regions such as northern Wisconsin. We evaluated the relative importance of wetland export in the MeHg budget of a wetland-dominated lake in northern Wisconsin usi

Popular AbstractDetta är en histora över teorier om ojämnt utbyte och deras upphovsmän. Den börjar med merkantilismen och Richard Cantillons jordvärdeteori, ger en kort beskrivning av tidig klassisk ekonomi och Gerald Fitzhugh. Bland det tidiga 1900-talets marxistiska ekonomer spelade ojämnt utbyte en roll i Otto Bauers tolkning av nationalistiska motsättningar, och i Henryk Grossmanns verk som enThis is a history of theories and theorists of unequal exchange. Starting with mercantilists and Richard Cantillon's theory based on land values, it briefly covers the early Classical economists and Gerald Fitzhugh. Among early 20th century Marxist economists, unequal exchange appeared in Otto Bauer's explanation of nationalist antagonism, and in Henryk Grossmann as countering the breakdown of cap

The production of forward jets has been measured in deep inelastic ep collisions at HERA. The results are presented in terms of single differential cross sections as a function of the Bjorken scaling variable (xB(j)) and as triple differential cross sections d3 sigma/dx(Bj)dQ(2)dp(t)(,jet)(2), where Q(2) is the four momentum transfer squared and p(t)(,iet)(2) is the squared transverse momentum of

Knowledge of the optical properties of tissues can be applied in numerous medical and scientific fields, including cancer diagnostics and therapy. There are many different ways of determining the optical properties of turbid media. The paper describes measurements of the optical properties of porcine brain tissue using novel instrumentation for simultaneous absorption and scattering characterisati

Popular Abstract in Swedish Populärvetenskaplig sammanfattning på svenska Sjukdom i hjärtat är mycket vanligt i västvärlden. I Sverige lider 12% av befolkningen av hjärt-kärlsjukdomar. Akut hjärtinfarkt är den vanligaste enskilda dödsorsaken. Sjukdomar i hjärtats kranskärl och deras komplikationer förorsakar totalt cirka 25% av alla dödsfall i Sverige. Hjärtsjukdom beror främst på förträngningar Evaluation of myocardial perfusion and function is important in management of patients with suspected or known coronary artery disease. This thesis focuses on the use of common diagnostic methods, myocardial perfusion single-photon emission computed tomography (MPS) and electrocardiography (ECG), to enhance and validate the diagnostic information. Cardiac magnetic resonance imaging (MRI) was used

An evaluation and review of a structurally related group of fragrance materials.

We have carried out accurate, systematic calculations for the 2s2p(3 5)S(2)(o)-2s(2)2p(2 3)P(1,2) E1] lines at 1660.807 and 1666.153 Angstrom in O III. Uncertainty estimates for their A values and the lifetime of the S-5(2)o level have been determined from a set of quality criteria. A lifetime of 1.21 +/- 0.06 ms is recommended for this level, in excellent agreement with a recent experiment. The c

Det folkhälsopedagogiska programmet vid högskolan i Kristianstad startade 1998 och kan ses som ett svar på de nya krav som samhället ställer på kompetens inom hälsoområdet, där sjukvårdande insatser ska ersättas eller kompletteras med hälsofrämjande arbete och där den pedagogiska dimensionen har ansetts särskilt viktig. Förutom att utbildningen ska vara relevant för den kommande yrkesfunktionen måThe aims of this thesis were to study how the students in the work experience period of The Study Program in Public Health and Education experienced how the discipline of education could contribute to health promotion in practice and if whether the integration between theory and practice in this case reached the appropriate higher education standard. The data collection comprised semi-structured i