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Comparative Proton and Photon Treatment Planning in Pediatric Patients with Various Diagnoses

Purpose: Radiation therapy with protons, owing to its physical properties, can beadvantageous for the treatment of children. This study was conducted in order to quantify the advantages of proton therapy from a treatment planning point of view in a consecutive, realistic, and mixed pediatric/adolescent population with varying diagnoses and target locations.Patients and Methods: Forty-five patients

Targeting prostate cancer stem cells with alpha-particle therapy

Modern molecular and radiopharmaceutical development has brought the promise of tumor-selective delivery of antibody-drug conjugates to tumor cells for the diagnosis and treatment of primary and disseminated tumor disease. The classical mode of discourse regarding targeted therapy has been that the antigen targeted must be highly and homogenously expressed in the tumor cell population, and at the

Disintegrated experience : The dissociative disorders revisited

We present proposed changes to the dissociative disorders section of the 4th edition of the Diagnostic and Statistical Manual of Mental Disorders and review the concept of pathological and nonpathological dissociation, including empirical findings on the relations between trauma and dissociative phenomenology and between dissociation and hypnosis. The most important proposals include the creation

P–T evolution of Precambrian eclogite in the Sveconorwegian orogen, SW Sweden

Conditions of the prograde, peak-pressure and part of the decompressional P–T path of two Precambrian eclogites in the eastern Sveconorwegian orogen have been determined using the pseudosection approach. Cores of garnet from a Fe–Ti-rich eclogite record a first prograde and syn-deformational stage along a Barrovian gradient from ~670 °C and 7 kbar to 710 °C and 8.5 kbar. Garnet rims grew during fu

Handelns digitalisering : Undran inför framtidens affärer

Handeln har länge kretsat kring det personliga mötet där den fysiska butiken – affären – har spelat en betydande roll för hur affärer görs. När handeln nu digitaliseras väcks en rad frågor om hur framtidens affärer kommer att se ut. I boken problematiseras och diskuteras handelns digitalisering med utgångspunkt i den fysiska butiken. Vidare behandlas vad som skapar värde för affären och affärerna

Finansministern i domkapitlet : Ernst Wigforss som ledamot av Göteborgs domkapitel 1918−1936

Ernst Wigforss (1881−1977) was Minister of Finance in Sweden 1925−26, 1932−36, and 1936−49, and one of the great ideologists of Swedish SocialDemocracy. During 1918−36 he was also a member of the Chapter in the Diocese of Gothenburg, Church of Sweden.Before 1937, lecturers in the old grammar schools were ex officiomembers of the diocesan chapter. The agnostic Wigforss took his seat in the chapter