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Byggnadssektorn stod för 39 % av energi- och processrelaterade koldioxidutsläpp år 2018 och globala utsläpp från byggnader ökade med 2 % för det andra året i rad. Därför är det viktigt att ta fram lösningar på byggnadsdesign som minimerar klimatpåverkan från byggnader. Samtidigt som produktionen av bostäder och kommersiella byggnader måste vara kostnadseffektiv för att skapa boende och arbetsplatsThe building and construction sector accounted for 39% of energy and process-related carbon dioxide emissions in 2018 and global emissions from buildings increased by 2% for the second consecutive year. It is therefore important to find building design solutions that minimise the climate impact of buildings. At the same time, the production of residential houses and commercial buildings must be co

The daily transition between day and night, known as the diel cycle, is characterised by significant shifts in environmental conditions and biological activity, both of which can affect crucial ecosystem functions like pollination. Despite over six decades of research into whether pollination varies between day and night, consensus remains elusive. We compiled the evidence of diel pollination from

Background: Alzheimer’s disease is a progressive, irreversible, and fatal disease for which accumulation of amyloid beta is thought to play a key role in pathogenesis. Aducanumab is a human monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid beta. Objectives: We evaluated the efficacy and safety of aducanumab in early Alzheimer’s disease. Design: EMERGE and ENGAG

Antibody-based microarrays are among the new, rapidly emerging technologies within the field of proteomics that has the potential to evolve into a key proteomic research tool, providing novel means to perform early diagnostics, identify biomarkers and gain insights into disease biology. The aim of this thesis, based on five original papers, was to develop antibody microarrays based on human recom

The increasing threat of soil degradation presents significant challenges to soil health, especially within agroecosystems that are vital for food security, climate regulation, and economic stability. This growing concern arises from intricate interactions between land use practices and climatic conditions, which, if not addressed, could jeopardize sustainable development and environmental resilie

Understanding the basic biology of both a host and the pathogens they are afflicted by is a prerequisite for the development of effective clinical interventions. Mycobacterium tuberculosis, the causative agent of tuberculosis, remains one of the leading causes of disease worldwide. Despite extensive research, the appearance of highly drug-resistant bacterial strains and the prevalence of HIV co-in

Although climate change and international trade are interdependent, policy-makers often address the two topics separately. This may inhibit progress at the intersection of climate change and trade and could present a serious constraint for global climate action. One key risk is carbon leakage through emission outsourcing, i.e. reductions in emissions in countries with rigorous climate policies bei

In this chapter, I introduce an analytical framework to explain a particular type of institutional interplay— conflicts among international regimes—and to support the analysis of interplay management within institutional complexes. Over the past two decades, regime conflicts have become more frequent in global environmental governance, sometimes including not only environmental regimes but also re

The organisational network of global environmental governance (GEG) mirrors the complexity of the planet's manifold and overlapping ecosystems. Bursting onto the international stage in the 1970s, environmental issues began to be addressed by a series of new international organisations, most of them affiliated with the United Nations. Some of them, such as the United Nations Environment Programme (

If we are to limit global warming to 2 °C, all sectors in all countries must reduce their emissions of GHGs to zero not later than 2060–2080. Zero-emission options have been less explored and are less developed in the energy-intensive basic materials industries than in other sectors. Current climate policies have not yet motivated major efforts to decarbonize this sector, and it has been largely p

In 2022, the United Nations Environmental Assembly (UNEA) adopted resolution 5/14, giving mandate to UN Member States to start negotiations toward an international legally binding instrument on plastic pollution. This report delves into the pre-session submissions by states and coalitions for the second (INC-2) and third (INC-3) rounds of negotiations, held in 2023. Once the contents of the docume

Changes in forest cover have a strong effect on climate through the alteration of surface biogeophysical and biogeochemical properties that affect energy, water and carbon exchange with the atmosphere. To quantify biogeophysical and biogeochemical effects of deforestation in a consistent setup, nine Earth system models (ESMs) carried out an idealized experiment in the framework of the Coupled Mode

We discuss how multinational enterprises (MNEs) can play a leading role and take more responsibility towards reducing inequalities by developing a global sustainability regime. We especially focus on how this may contribute towards the United Nations’ Sustainable Development Goals (UN SDGs). Our purpose is to identify and discuss the components and activities that are needed to develop such a stra

Ecological intensification has been embraced with great interest by the academic sector but is still rarely taken up by farmers because monitoring the state of different ecological functions is not straightforward. Modelling tools can represent a more accessible alternative of measuring ecological functions, which could help promote their use amongst farmers and other decision-makers. In the case

Popular Abstract in Swedish Stroke och hjärtstopp innebär ett minskat eller obefintligt blodflöde (ischemi) till hjärnans celler. Dessa celler är speciellt känliga för ischemi och om blodtflödet är lågt under en längre period leder det till obotliga hjärnskador. Varje år drabbas ungefär 50 000 personer i Sverige av hjärnischemi, vilket gör tillståndet till ett av de vanligaste orsakerna till handiCerebral ischemia is a major cause of mortality and morbidity in the western world. Even though much effort has been put into research and development of effective drugs against ischemic damage there is to date no effective pharmacological brain protective treatment. In order to study particular molecular mechanisms, isolated cellular events and the contribution of individual factors in ischemic d